Molecular pathways enhance drug response prediction using transfer learning from cell lines to tumors and patient-derived xenografts

por Tang, Yi-Ching, Powell, Reid T., Gottlieb, Assaf
Publicado 2022

Identification of Histological Correlates of Overall Survival in Lower Grade Gliomas Using a Bag-of-words Paradigm: A Preliminary Analysis Based on Hematoxylin & Eosin Stained Slid...

por Powell, Reid Trenton, Olar, Adriana, Narang, Shivali, Rao, Ganesh, Sulman, Erik, Fuller, Gregory N., Rao, Arvind
Publicado 2017

Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-α

por Bolt, Michael J., Singh, Pankaj, Obkirchner, Caroline E., Powell, Reid T., Mancini, Maureen G., Szafran, Adam T., Stossi, Fabio, Mancini, Michael A.
Publicado 2021

Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo

por Fan, Fan, Ghosh, Susmita, Powell, Reid, Roszik, Jason, Park, Yongsun, Sobieski, Mary, Sorokin, Alexey, Stephan, Clifford, Kopetz, Scott, Ellis, Lee M., Bhattacharya, Rajat
Publicado 2023

High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na(+) channel complex

por Wadsworth, Paul A., Folorunso, Oluwarotimi, Nguyen, Nghi, Singh, Aditya K., D’Amico, Daniela, Powell, Reid T., Brunell, David, Allen, John, Stephan, Clifford, Laezza, Fernanda
Publicado 2019

Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

por Chowdhury, Pratim, Perera, Dimuthu, Powell, Reid T., Talley, Tia, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Stephan, Clifford, Coarfa, Cristian, Dere, Ruhee
Publicado 2021

Author Correction: Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

por Chowdhury, Pratim, Perera, Dimuthu, Powell, Reid T., Talley, Tia, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Stephan, Clifford, Coarfa, Cristian, Dere, Ruhee
Publicado 2021

Bexarotene – a novel modulator of AURKA and the primary cilium in VHL-deficient cells

por Chowdhury, Pratim, Powell, Reid T., Stephan, Clifford, Uray, Ivan P., Talley, Tia, Karki, Menuka, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Dere, Ruhee
Publicado 2018

The Transcription Factor ETV5 Mediates BRAFV600E-Induced Proliferation and TWIST1 Expression in Papillary Thyroid Cancer Cells()

por Puli, Oorvashi Roy, Danysh, Brian P, McBeath, Elena, Sinha, Deepankar K, Hoang, Nguyet M, Powell, Reid T, Danysh, Heather E, Cabanillas, Maria E, Cote, Gilbert J, Hofmann, Marie-Claude
Publicado 2018

Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas

por de Groot, Evelyn, Varghese, Sruthy, Tan, Lin, Knighton, Barbara, Sobieski, Mary, Nguyen, Nghi, Park, Yong Sung, Powell, Reid, Lorenzi, Philip L., Zheng, Bin, Stephan, Clifford, Gopal, Y. N. Vashisht
Publicado 2022

Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

por Zhao, Na, Powell, Reid T., Yuan, Xueying, Bae, Goeun, Roarty, Kevin P., Stossi, Fabio, Strempfl, Martina, Toneff, Michael J., Johnson, Hannah L., Mani, Sendurai A., Jones, Philip, Stephan, Clifford C., Rosen, Jeffrey M.
Publicado 2021

ATM Functions at the Peroxisome to Induce Pexophagy in Response to ROS

por Zhang, Jiangwei, Tripathi, Durga Nand, Jing, Ji, Alexander, Angela, Kim, Jinhee, Powell, Reid T., Dere, Ruhee, Tait-Mulder, Jacqueline, Lee, Ji-Hoon, Paull, Tanya T., Pandita, Raj K., Charaka, Vijaya K., Pandita, Tej K., Kastan, Michael B., Walker, Cheryl Lyn
Publicado 2015

Combination of EphA2- and Wee1-Targeted Therapies in Endometrial Cancer

por Dasari, Santosh K., Joseph, Robiya, Umamaheswaran, Sujanitha, Mangala, Lingegowda S., Bayraktar, Emine, Rodriguez-Aguayo, Cristian, Wu, Yutuan, Nguyen, Nghi, Powell, Reid T., Sobieski, Mary, Liu, Yuan, Chowdhury, Mamur A., Amero, Paola, Stephan, Clifford, Lopez-Berestein, Gabriel, Westin, Shannon N., Sood, Anil K.
Publicado 2023

Screening of GPCR drugs for repurposing in breast cancer

por Abdulkareem, Noor Mazin, Bhat, Raksha, Powell, Reid T., Chikermane, Soumya, Yande, Soham, Trinh, Lisa, Abdelnasser, Hala Y., Tabassum, Mantasha, Ruiz, Alexis, Sobieski, Mary, Nguyen, Nghi D., Park, Jun Hyoung, Johnson, Camille A., Kaipparettu, Benny A., Bond, Richard A., Johnson, Michael, Stephan, Clifford, Trivedi, Meghana V.
Publicado 2022

Chemically targeting the redox switch in AP1 transcription factor ΔFOSB

por Kumar, Ashwani, Aglyamova, Galina, Yim, Yun Young, Bailey, Aaron O, Lynch, Haley M, Powell, Reid T, Nguyen, Nghi D, Rosenthal, Zachary, Zhao, Wen-Ning, Li, Yi, Chen, Jianping, Fan, Shanghua, Lee, Hubert, Russell, William K, Stephan, Clifford, Robison, Alfred J, Haggarty, Stephen J, Nestler, Eric J, Zhou, Jia, Machius, Mischa, Rudenko, Gabby
Publicado 2022

Pharmacologic profiling of patient-derived xenograft models of primary treatment-naïve triple-negative breast cancer

por Powell, Reid T., Redwood, Abena, Liu, Xuan, Guo, Lei, Cai, Shirong, Zhou, Xinhui, Tu, Yizheng, Zhang, Xiaomei, Qi, Yuan, Jiang, Yan, Echeverria, Gloria, Feng, Ningping, Ma, XiaoYan, Giuliani, Virginia, Marszalek, Joseph R., Heffernan, Timothy P., Vellano, Christopher P., White, Jason B., Stephan, Clifford, Davies, Peter J., Moulder, Stacy, Symmans, W. Fraser, Chang, Jeffrey T., Piwnica-Worms, Helen
Publicado 2020

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

por Shah, Vrutant V., Duncan, Aundrietta D., Jiang, Shiming, Stratton, Sabrina A., Allton, Kendra L., Yam, Clinton, Jain, Abhinav, Krause, Patrick M., Lu, Yue, Cai, Shirong, Tu, Yizheng, Zhou, Xinhui, Zhang, Xiaomei, Jiang, Yan, Carroll, Christopher L., Kang, Zhijun, Liu, Bin, Shen, Jianjun, Gagea, Mihai, Manu, Sebastian M., Huo, Lei, Gilcrease, Michael, Powell, Reid T., Guo, Lei, Stephan, Clifford, Davies, Peter J., Parker-Thornburg, Jan, Lozano, Guillermina, Behringer, Richard R., Piwnica-Worms, Helen, Chang, Jeffrey T., Moulder, Stacy L., Barton, Michelle Craig
Publicado 2021