Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association St...

por Lu, Qiongshi, Powles, Ryan Lee, Wang, Qian, He, Beixin Julie, Zhao, Hongyu
Publicado 2016

Leveraging functional annotations in genetic risk prediction for human complex diseases

por Hu, Yiming, Lu, Qiongshi, Powles, Ryan, Yao, Xinwei, Yang, Can, Fang, Fang, Xu, Xinran, Zhao, Hongyu
Publicado 2017

Scalable and cost-effective NGS genotyping in the cloud

por Souilmi, Yassine, Lancaster, Alex K., Jung, Jae-Yoon, Rizzo, Ettore, Hawkins, Jared B., Powles, Ryan, Amzazi, Saaïd, Ghazal, Hassan, Tonellato, Peter J., Wall, Dennis P.
Publicado 2015

Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer’s disease

por Lu, Qiongshi, Powles, Ryan L., Abdallah, Sarah, Ou, Derek, Wang, Qian, Hu, Yiming, Lu, Yisi, Liu, Wei, Li, Boyang, Mukherjee, Shubhabrata, Crane, Paul K., Zhao, Hongyu
Publicado 2017

Genomic and Immune Profiling of a Patient With Triple-Negative Breast Cancer That Progressed During Neoadjuvant Chemotherapy Plus PD-L1 Blockade

por Casadevall, David, Li, Xiaotong, Powles, Ryan L., Wali, Vikram B., Buza, Natalia, Pelekanou, Vasiliki, Dhawan, Arjun, Foldi, Julia, Szekely, Borbala, Lopez-Giraldez, Francesc, Hatzis, Christos, Pusztai, Lajos
Publicado 2019

CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

por Feng, William W., Wilkins, Owen, Bang, Scott, Ung, Matthew, Li, Jiaqi, An, Jennifer, del Genio, Carmen, Canfield, Kaleigh, DiRenzo, James, Wells, Wendy, Gaur, Arti, Robey, R. Brooks, Guo, Jessie Yanxiang, Powles, Ryan L., Sotiriou, Christos, Pusztai, Lajos, Febbraio, Maria, Cheng, Chao, Kinlaw, William B., Kurokawa, Manabu
Publicado 2019