Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity

por Franks, Lirit N., Ford, Benjamin M., Prather, Paul L.
Publicado 2016

Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development

por Ford, Benjamin M., Franks, Lirit N., Radominska-Pandya, Anna, Prather, Paul L.
Publicado 2016

Non-Canonical Cannabinoid Receptors with Distinct Binding and Signaling Properties in Prostate and Other Cancer Cell Types Mediate Cell Death

por Shoeib, Amal M., Benson, Lance N., Mu, Shengyu, MacMillan-Crow, Lee Ann, Prather, Paul L.
Publicado 2022

Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity

por Brents, Lisa K., Reichard, Emily E., Zimmerman, Sarah M., Moran, Jeffery H., Fantegrossi, William E., Prather, Paul L.
Publicado 2011

Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1H‐indole‐3‐carboxamide (STS‐135)

por Jones, Sabrina, Yarbrough, Azure L., Fantegrossi, William E., Prather, Paul L., Bush, John M., Radominska‐Pandya, Anna, Fujiwara, Ryoichi
Publicado 2020

Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics

por Pinson, Anna O., Pouncey, Dakota L., Schleiff, Mary A., Fantegrossi, William E., Prather, Paul L., Radominska-Pandya, Anna, Boysen, Gunnar, Miller, Grover P.
Publicado 2020

Non-Selective Cannabinoid Receptor Antagonists, Hinokiresinols Reduce Infiltration of Microglia/Macrophages into Ischemic Brain Lesions in Rat via Modulating 2-Arachidonolyglycerol...

por Anthony Jalin, Angela M. A., Rajasekaran, Maheswari, Prather, Paul L., Kwon, Jin Sun, Gajulapati, Veeraswamy, Choi, Yongseok, Kim, Chunsook, Pahk, Kisoo, Ju, Chung, Kim, Won-Ki
Publicado 2015

Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats

por Janganati, Venumadhav, Salazar, Paloma, Parks, Brian J., Gorman, Gregory S., Prather, Paul L., Peterson, Eric C., Alund, Alexander W., Moran, Jeffery H., Crooks, Peter A., Brents, Lisa K.
Publicado 2023

Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes

por Crosby, Samantha V., Ahmed, Izzeldin Y., Osborn, Laura R., Wang, Zeyuan, Schleiff, Mary A., Fantegrossi, William E., Nagar, Swati, Prather, Paul L., Boysen, Gunnar, Miller, Grover P.
Publicado 2022

Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ(9)-THC

por Hutchison, Rachel D., Ford, Benjamin M., Franks, Lirit N., Wilson, Catheryn D., Yarbrough, Azure L., Fujiwara, Ryoichi, Su, Mark K., Fernandez, Denise, James, Laura P., Moran, Jeffery H., Patton, Amy L., Fantegrossi, William E., Radominska-Pandya, Anna, Prather, Paul L.
Publicado 2018