Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer

por Bano, Daniele, Prehn, Jochen H.M.
Publicado 2018

Real-time single cell analysis of Smac/DIABLO release during apoptosis

por Rehm, Markus, Düßmann, Heiko, Prehn, Jochen H.M.
Publicado 2003

Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microgli...

por Kinsella, Sinéad, König, Hans-Georg, Prehn, Jochen H.M.
Publicado 2016

TGF-β1 activates two distinct type I receptors in neurons: implications for neuronal NF-κB signaling

por König, Hans-Georg, Kögel, Donat, Rami, Abdelhaq, Prehn, Jochen H.M.
Publicado 2005

Diffusion is capable of translating anisotropic apoptosis initiation into a homogeneous execution of cell death

por Huber, Heinrich J, Laussmann, Maike A, Prehn, Jochen HM, Rehm, Markus
Publicado 2010

BCL2 and BCL(X)L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2-deoxy-D-glucose

por Lucantoni, Federico, Düssmann, Heiko, Llorente-Folch, Irene, Prehn, Jochen H.M.
Publicado 2018

Gene expression during ER stress–induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

por Reimertz, Claus, Kögel, Donat, Rami, Abdelhaq, Chittenden, Thomas, Prehn, Jochen H.M.
Publicado 2003

Activation of Nuclear Factor κb and bcl-x Survival Gene Expression by Nerve Growth Factor Requires Tyrosine Phosphorylation of IκBα

por Bui, Nguyen Truc, Livolsi, Antonia, Peyron, Jean-Francois, Prehn, Jochen H.M.
Publicado 2001

Single-cell time-lapse imaging of intracellular O(2) in response to metabolic inhibition and mitochondrial cytochrome-c release

por Düssmann, Heiko, Perez-Alvarez, Sergio, Anilkumar, Ujval, Papkovsky, Dmitri B, Prehn, Jochen HM
Publicado 2017

Full Length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons

por König, Hans-Georg, Rehm, Markus, Gudorf, Daniel, Krajewski, Stan, Gross, Atan, Ward, Manus W, Prehn, Jochen HM
Publicado 2007

Serum levels of pancreatic stone protein (PSP)/reg1A as an indicator of beta-cell apoptosis suggest an increased apoptosis rate in hepatocyte nuclear factor 1 alpha (HNF1A-MODY) ca...

por Bacon, Siobhan, Kyithar, Ma Peyh, Schmid, Jasmin, Rizvi, Syed R, Bonner, Caroline, Graf, Rolf, Prehn, Jochen HM, Byrne, Maria M
Publicado 2012

Effects of hepatocyte nuclear factor-1A and -4A on pancreatic stone protein/regenerating protein and C-reactive protein gene expression: implications for maturity-onset diabetes of...

por Kyithar, Ma P, Bonner, Caroline, Bacon, Siobhan, Kilbride, Seán M, Schmid, Jasmin, Graf, Rolf, Prehn, Jochen HM, Byrne, Maria M
Publicado 2013

Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice

por Ichikawa, Naoki, Alves, Mariana, Pfeiffer, Shona, Langa, Elena, Hernández-Santana, Yasmina E, Suzuki, Hidenori, Prehn, Jochen HM, Engel, Tobias, Henshall, David C
Publicado 2017

TRAIL signaling promotes entosis in colorectal cancer

por Bozkurt, Emir, Düssmann, Heiko, Salvucci, Manuela, Cavanagh, Brenton L., Van Schaeybroeck, Sandra, Longley, Daniel B., Martin, Seamus J., Prehn, Jochen H.M.
Publicado 2021

Quantification of substoichiometric modification reveals global tsRNA hypomodification, preferences for angiogenin-mediated tRNA cleavage, and idiosyncratic epitranscriptomes of hu...

por Pichot, Florian, Hogg, Marion C., Marchand, Virginie, Bourguignon, Valérie, Jirström, Elisabeth, Farrell, Cliona, Gibriel, Hesham A., Prehn, Jochen H.M., Motorin, Yuri, Helm, Mark
Publicado 2022

AMP kinase–mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

por Concannon, Caoimhín G., Tuffy, Liam P., Weisová, Petronela, Bonner, Helena P., Dávila, David, Bonner, Caroline, Devocelle, Marc C., Strasser, Andreas, Ward, Manus W., Prehn, Jochen H.M.
Publicado 2010

Master Transcription Regulators and Transcription Factors Regulate Immune-Associated Differences Between Patients of African and European Ancestry With Colorectal Cancer

por Myer, Parvathi A., Kim, Hyunjin, Blümel, Anna M., Finnegan, Ellen, Kel, Alexander, Thompson, Taylor V., Greally, John M., Prehn, Jochen HM., O’Connor, Darran P., Friedman, Richard A., Floratos, Aris, Das, Sudipto
Publicado 2022

INS-1 Cells Undergoing Caspase-Dependent Apoptosis Enhance the Regenerative Capacity of Neighboring Cells

por Bonner, Caroline, Bacon, Siobhán, Concannon, Caoimhín G., Rizvi, Syed R., Baquié, Mathurin, Farrelly, Angela M., Kilbride, Seán M., Dussmann, Heiko, Ward, Manus W., Boulanger, Chantal M., Wollheim, Claes B., Graf, Rolf, Byrne, Maria M., Prehn, Jochen H.M.
Publicado 2010

Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance...

por Tivnan, Amanda, Heilinger, Tatjana, Ramsey, Joanne M, O’Connor, Gemma, Pokorny, Jenny L, Sarkaria, Jann N, Stringer, Brett W, Day, Bryan W, Boyd, Andrew W, Kim, Ella L, Lode, Holger N, Cryan, Sally-Ann, Prehn, Jochen H.M
Publicado 2017

Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy

por Raoof, Rana, Bauer, Sebastian, El Naggar, Hany, Connolly, Niamh M.C., Brennan, Gary P., Brindley, Elizabeth, Hill, Thomas, McArdle, Hazel, Spain, Elaine, Forster, Robert J., Prehn, Jochen H.M., Hamer, Hajo, Delanty, Norman, Rosenow, Felix, Mooney, Catherine, Henshall, David C.
Publicado 2018