Pdgfra marks a cellular lineage with distinct contributions to myofibroblasts in lung maturation and injury response

por Li, Rongbo, Bernau, Ksenija, Sandbo, Nathan, Gu, Jing, Preissl, Sebastian, Sun, Xin
Publicado 2018

Cardiac Myocyte De Novo DNA Methyltransferases 3a/3b Are Dispensable for Cardiac Function and Remodeling after Chronic Pressure Overload in Mice

por Nührenberg, Thomas G., Hammann, Nils, Schnick, Tilman, Preißl, Sebastian, Witten, Anika, Stoll, Monika, Gilsbach, Ralf, Neumann, Franz-Josef, Hein, Lutz
Publicado 2015

DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes

por Nothjunge, Stephan, Nührenberg, Thomas G., Grüning, Björn A., Doppler, Stefanie A., Preissl, Sebastian, Schwaderer, Martin, Rommel, Carolin, Krane, Markus, Hein, Lutz, Gilsbach, Ralf
Publicado 2017

Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage Relationships

por Chung, Chi-Yeh, Ma, Zhibo, Dravis, Christopher, Preissl, Sebastian, Poirion, Olivier, Luna, Gidsela, Hou, Xiaomeng, Giraddi, Rajshekhar R., Ren, Bing, Wahl, Geoffrey M.
Publicado 2019

Single-cell epigenome analysis reveals age-associated decay of heterochromatin domains in excitatory neurons in the mouse brain

por Zhang, Yanxiao, Amaral, Maria Luisa, Zhu, Chenxu, Grieco, Steven Francis, Hou, Xiaomeng, Lin, Lin, Buchanan, Justin, Tong, Liqi, Preissl, Sebastian, Xu, Xiangmin, Ren, Bing
Publicado 2022

Single-Cell Chromatin Accessibility Maps Reveal Regulatory Programs Driving Early Mouse Organogenesis

por Pijuan-Sala, Blanca, Wilson, Nicola K., Xia, Jun, Hou, Xiaomeng, Hannah, Rebecca L., Kinston, Sarah, Calero-Nieto, Fernando J., Poirion, Olivier, Preissl, Sebastian, Liu, Feng, Göttgens, Berthold
Publicado 2020

Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral blood

por Benaglio, Paola, Newsome, Jacklyn, Han, Jee Yun, Chiou, Joshua, Aylward, Anthony, Corban, Sierra, Miller, Michael, Okino, Mei-Lin, Kaur, Jaspreet, Preissl, Sebastian, Gorkin, David U., Gaulton, Kyle J.
Publicado 2023

Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease

por Gilsbach, Ralf, Preissl, Sebastian, Grüning, Björn A., Schnick, Tilman, Burger, Lukas, Benes, Vladimir, Würch, Andreas, Bönisch, Ulrike, Günther, Stefan, Backofen, Rolf, Fleischmann, Bernd K., Schübeler, Dirk, Hein, Lutz
Publicado 2014

Iterative single-cell multi-omic integration using online learning

por Gao, Chao, Liu, Jialin, Kriebel, April R., Preissl, Sebastian, Luo, Chongyuan, Castanon, Rosa, Sandoval, Justin, Rivkin, Angeline, Nery, Joseph R., Behrens, Margarita M., Ecker, Joseph R., Ren, Bing, Welch, Joshua D.
Publicado 2021

Comprehensive analysis of single cell ATAC-seq data with SnapATAC

por Fang, Rongxin, Preissl, Sebastian, Li, Yang, Hou, Xiaomeng, Lucero, Jacinta, Wang, Xinxin, Motamedi, Amir, Shiau, Andrew K., Zhou, Xinzhu, Xie, Fangming, Mukamel, Eran A., Zhang, Kai, Zhang, Yanxiao, Behrens, M. Margarita, Ecker, Joseph R., Ren, Bing
Publicado 2021

Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

por Gilsbach, Ralf, Schwaderer, Martin, Preissl, Sebastian, Grüning, Björn A., Kranzhöfer, David, Schneider, Pedro, Nührenberg, Thomas G., Mulero-Navarro, Sonia, Weichenhan, Dieter, Braun, Christian, Dreßen, Martina, Jacobs, Adam R., Lahm, Harald, Doenst, Torsten, Backofen, Rolf, Krane, Markus, Gelb, Bruce D., Hein, Lutz
Publicado 2018

The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling

por Gally, Fabienne, Sasse, Sarah K., Kurche, Jonathan S., Gruca, Margaret A., Cardwell, Jonathan H., Okamoto, Tsukasa, Chu, Hong W., Hou, Xiaomeng, Poirion, Olivier B., Buchanan, Justin, Preissl, Sebastian, Ren, Bing, Colgan, Sean P., Dowell, Robin D., Yang, Ivana V., Schwartz, David A., Gerber, Anthony N.
Publicado 2021

Cardiac cell type–specific gene regulatory programs and disease risk association

por Hocker, James D., Poirion, Olivier B., Zhu, Fugui, Buchanan, Justin, Zhang, Kai, Chiou, Joshua, Wang, Tsui-Min, Zhang, Qingquan, Hou, Xiaomeng, Li, Yang E., Zhang, Yanxiao, Farah, Elie N., Wang, Allen, McCulloch, Andrew D., Gaulton, Kyle J., Ren, Bing, Chi, Neil C., Preissl, Sebastian
Publicado 2021

Single cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk

por Chiou, Joshua, Zeng, Chun, Cheng, Zhang, Han, Jee Yun, Schlichting, Michael, Miller, Michael, Mendez, Robert, Huang, Serina, Wang, Jinzhao, Sui, Yinghui, Deogaygay, Allison, Okino, Mei-Lin, Qiu, Yunjiang, Sun, Ying, Kudtarkar, Parul, Fang, Rongxin, Preissl, Sebastian, Sander, Maike, Gorkin, David U, Gaulton, Kyle J
Publicado 2021

Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes

por Xie, Fangming, Armand, Ethan J., Yao, Zizhen, Liu, Hanqing, Bartlett, Anna, Behrens, M. Margarita, Li, Yang Eric, Lucero, Jacinta D., Luo, Chongyuan, Nery, Joseph R., Pinto-Duarte, Antonio, Poirion, Olivier B., Preissl, Sebastian, Rivkin, Angeline C., Tasic, Bosiljka, Zeng, Hongkui, Ren, Bing, Ecker, Joseph R., Mukamel, Eran A.
Publicado 2023

Transcriptionally Active HERV-H Retrotransposons Demarcate Topologically Associating Domains in Human Pluripotent Stem Cells

por Zhang, Yanxiao, Li, Ting, Preissl, Sebastian, Amaral, Maria Luisa, Grinstein, Jonathan, Farah, Elie N., Destici, Eugin, Qiu, Yunjiang, Hu, Rong, Lee, Ah Young, Chee, Sora, Ma, Kaiyue, Ye, Zhen, Zhu, Quan, Huang, Hui, Fang, Rongxin, Yu, Leqian, Belmonte, Juan Carlos Izpisua, Wu, Jun, Evans, Sylvia M., Chi, Neil C., Ren, Bing
Publicado 2019

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines

por Benaglio, Paola, Zhu, Han, Okino, Mei-Lin, Yan, Jian, Elgamal, Ruth, Nariai, Naoki, Beebe, Elisha, Korgaonkar, Katha, Qiu, Yunjiang, Donovan, Margaret K.R., Chiou, Joshua, Wang, Gaowei, Newsome, Jacklyn, Kaur, Jaspreet, Miller, Michael, Preissl, Sebastian, Corban, Sierra, Aylward, Anthony, Taipale, Jussi, Ren, Bing, Frazer, Kelly A., Sander, Maike, Gaulton, Kyle J.
Publicado 2022

Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes

por Wang, Gaowei, Chiou, Joshua, Zeng, Chun, Miller, Michael, Matta, Ileana, Han, Jee Yun, Kadakia, Nikita, Okino, Mei-Lin, Beebe, Elisha, Mallick, Medhavi, Camunas-Soler, Joan, dos Santos, Theodore, Dai, Xiao-Qing, Ellis, Cara, Hang, Yan, Kim, Seung K., MacDonald, Patrick E., Kandeel, Fouad R., Preissl, Sebastian, Gaulton, Kyle J, Sander, Maike
Publicado 2023

Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity

por Raviram, Ramya, Raman, Anugraha, Preissl, Sebastian, Ning, Jiangfang, Wu, Shaoping, Koga, Tomoyuki, Zhang, Kai, Brennan, Cameron W., Zhu, Chenxu, Luebeck, Jens, Van Deynze, Kinsey, Han, Jee Yun, Hou, Xiaomeng, Ye, Zhen, Mischel, Anna K., Li, Yang Eric, Fang, Rongxin, Baback, Tomas, Mugford, Joshua, Han, Claudia Z., Glass, Christopher K., Barr, Cathy L., Mischel, Paul S., Bafna, Vineet, Escoubet, Laure, Ren, Bing, Chen, Clark C.
Publicado 2023

Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure

por Mayer, Sandra C., Gilsbach, Ralf, Preissl, Sebastian, Monroy Ordonez, Elsa Beatriz, Schnick, Tilman, Beetz, Nadine, Lother, Achim, Rommel, Carolin, Ihle, Hannah, Bugger, Heiko, Rühle, Frank, Schrepper, Andrea, Schwarzer, Michael, Heilmann, Claudia, Bönisch, Ulrike, Gupta, Shashi Kumar, Wilpert, Jochen, Kretz, Oliver, von Elverfeldt, Dominik, Orth, Joachim, Aktories, Klaus, Beyersdorf, Friedhelm, Bode, Christoph, Stiller, Brigitte, Krüger, Markus, Thum, Thomas, Doenst, Torsten, Stoll, Monika, Hein, Lutz
Publicado 2015