SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells

por Nchioua, Rayhane, Schundner, Annika, Kmiec, Dorota, Prelli Bozzo, Caterina, Zech, Fabian, Koepke, Lennart, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Frick, Manfred, Sparrer, Konstantin M. J., Kirchhoff, Frank
Publicado 2022

Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells

por Bosso, Matteo, Prelli Bozzo, Caterina, Hotter, Dominik, Volcic, Meta, Stürzel, Christina M., Rammelt, Annika, Ni, Yi, Urban, Stephan, Becker, Miriam, Schelhaas, Mario, Wittmann, Sabine, Christensen, Maria H., Schmidt, Florian I., Gramberg, Thomas, Sparrer, Konstantin M. J., Sauter, Daniel, Kirchhoff, Frank
Publicado 2020

Spike residue 403 affects binding of coronavirus spikes to human ACE2

por Zech, Fabian, Schniertshauer, Daniel, Jung, Christoph, Herrmann, Alexandra, Cordsmeier, Arne, Xie, Qinya, Nchioua, Rayhane, Prelli Bozzo, Caterina, Volcic, Meta, Koepke, Lennart, Müller, Janis A., Krüger, Jana, Heller, Sandra, Stenger, Steffen, Hoffmann, Markus, Pöhlmann, Stefan, Kleger, Alexander, Jacob, Timo, Conzelmann, Karl-Klaus, Ensser, Armin, Sparrer, Konstantin M. J., Kirchhoff, Frank
Publicado 2021

Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIV(mac239) in rhesus macaques

por Laliberté, Alexandre, Prelli Bozzo, Caterina, Stahl-Hennig, Christiane, Hunszinger, Victoria, Joas, Simone, Sauermann, Ulrike, Roshani, Berit, Klippert, Antonina, Daskalaki, Maria, Mätz-Rensing, Kerstin, Stolte-Leeb, Nicole, Tharp, Gregory K., Fuchs, Dietmar, Gupta, Prachi Mehrotra, Silvestri, Guido, Nelson, Sydney A., Parodi, Laura, Giavedoni, Luis, Bosinger, Steven E., Sparrer, Konstantin M.J., Kirchhoff, Frank
Publicado 2023

Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities

por Hayn, Manuel, Hirschenberger, Maximilian, Koepke, Lennart, Nchioua, Rayhane, Straub, Jan Hendrik, Klute, Susanne, Hunszinger, Victoria, Zech, Fabian, Prelli Bozzo, Caterina, Aftab, Wasim, Christensen, Maria Hønholt, Conzelmann, Carina, Müller, Janis Alexander, Srinivasachar Badarinarayan, Smitha, Stürzel, Christina Martina, Forne, Ignasi, Stenger, Steffen, Conzelmann, Karl-Klaus, Münch, Jan, Schmidt, Florian Ingo, Sauter, Daniel, Imhof, Axel, Kirchhoff, Frank, Sparrer, Konstantin Maria Johannes
Publicado 2021

Antimicrobial Activity of Cyclic-Monomeric and Dimeric Derivatives of the Snail-Derived Peptide Cm-p5 against Viral and Multidrug-Resistant Bacterial Strains

por González-García, Melaine, Morales-Vicente, Fidel, Pico, Erbio Díaz, Garay, Hilda, Rivera, Daniel G., Grieshober, Mark, Raluca Olari, Lia, Groß, Rüdiger, Conzelmann, Carina, Krüger, Franziska, Zech, Fabian, Prelli Bozzo, Caterina, Müller, Janis A., Zelikin, Alexander, Raber, Heinz, Kubiczek, Dennis, Rosenau, Frank, Münch, Jan, Stenger, Steffen, Spellerberg, Barbara, Franco, Octavio L., Rodriguez Alfonso, Armando A., Ständker, Ludger, Otero-Gonzalez, Anselmo J.
Publicado 2021

Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection

por Wettstein, Lukas, Weil, Tatjana, Conzelmann, Carina, Müller, Janis A., Groß, Rüdiger, Hirschenberger, Maximilian, Seidel, Alina, Klute, Susanne, Zech, Fabian, Prelli Bozzo, Caterina, Preising, Nico, Fois, Giorgio, Lochbaum, Robin, Knaff, Philip Maximilian, Mailänder, Volker, Ständker, Ludger, Thal, Dietmar Rudolf, Schumann, Christian, Stenger, Steffen, Kleger, Alexander, Lochnit, Günter, Mayer, Benjamin, Ruiz-Blanco, Yasser B., Hoffmann, Markus, Sparrer, Konstantin M. J., Pöhlmann, Stefan, Sanchez-Garcia, Elsa, Kirchhoff, Frank, Frick, Manfred, Münch, Jan
Publicado 2021

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro

por Prelli Bozzo, Caterina, Nchioua, Rayhane, Volcic, Meta, Koepke, Lennart, Krüger, Jana, Schütz, Desiree, Heller, Sandra, Stürzel, Christina M., Kmiec, Dorota, Conzelmann, Carina, Müller, Janis, Zech, Fabian, Braun, Elisabeth, Groß, Rüdiger, Wettstein, Lukas, Weil, Tatjana, Weiß, Johanna, Diofano, Federica, Rodríguez Alfonso, Armando A., Wiese, Sebastian, Sauter, Daniel, Münch, Jan, Goffinet, Christine, Catanese, Alberto, Schön, Michael, Boeckers, Tobias M., Stenger, Steffen, Sato, Kei, Just, Steffen, Kleger, Alexander, Sparrer, Konstantin M. J., Kirchhoff, Frank
Publicado 2021