Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones

por Sugiyama, Toshihiro, Price, Joanna S., Lanyon, Lance E.
Publicado 2010

The Contribution of Experimental in vivo Models to Understanding the Mechanisms of Adaptation to Mechanical Loading in Bone

por Meakin, Lee B., Price, Joanna S., Lanyon, Lance E.
Publicado 2014

Sclerostin's role in bone's adaptive response to mechanical loading

por Galea, Gabriel L, Lanyon, Lance E, Price, Joanna S
Publicado 2017

Mechanical Loading-Related Bone Gain Is Enhanced by Tamoxifen but Unaffected by Fulvestrant in Female Mice

por Sugiyama, Toshihiro, Galea, Gabriel L., Lanyon, Lance E., Price, Joanna S.
Publicado 2010

Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the o...

por Saxon, Leanne K., Jackson, Brendan F., Sugiyama, Toshihiro, Lanyon, Lance E., Price, Joanna S.
Publicado 2011

Snail2 promotes osteosarcoma cell motility through remodelling of the actin cytoskeleton and regulates tumor development

por Sharili, Amir-Shaya, Allen, Steve, Smith, Ken, Price, Joanna, McGonnell, Imelda M.
Publicado 2013

Age-Related Impairment of Bones' Adaptive Response to Loading in Mice Is Associated With Sex-Related Deficiencies in Osteoblasts but No Change in Osteocytes†

por Meakin, Lee B, Galea, Gabriel L, Sugiyama, Toshihiro, Lanyon, Lance E, Price, Joanna S
Publicado 2014

Exercise does not enhance aged bone's impaired response to artificial loading in C57Bl/6 mice

por Meakin, Lee B., Udeh, Chinedu, Galea, Gabriel L., Lanyon, Lance E., Price, Joanna S.
Publicado 2015

Bone gain following loading is site-specifically enhanced by prior and concurrent disuse in aged male mice

por Galea, Gabriel L., Delisser, Peter J., Meakin, Lee, Price, Joanna S., Windahl, Sara H.
Publicado 2020

Expression of Snail2 in long bone osteosarcomas correlates with tumour malignancy

por Sharili, Amir-Shaya, Allen, Steve, Smith, Ken, Hargreaves, Judith, Price, Joanna, McGonnell, Imelda
Publicado 2011

A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?

por McGonnell, Imelda M., Grigoriadis, Agamemnon E., Lam, Eric W.-F., Price, Joanna S., Sunters, Andrew
Publicado 2012

Bones' Adaptive Response to Mechanical Loading Is Essentially Linear Between the Low Strains Associated With Disuse and the High Strains Associated With the Lamellar/Woven Bone Tra...

por Sugiyama, Toshihiro, Meakin, Lee B, Browne, William J, Galea, Gabriel L, Price, Joanna S, Lanyon, Lance E
Publicado 2012

Male mice housed in groups engage in frequent fighting and show a lower response to additional bone loading than females or individually housed males that do not fight

por Meakin, Lee B., Sugiyama, Toshihiro, Galea, Gabriel L., Browne, William J., Lanyon, Lance E., Price, Joanna S.
Publicado 2013

Quantification of Alterations in Cortical Bone Geometry Using Site Specificity Software in Mouse models of Aging and the Responses to Ovariectomy and Altered Loading

por Galea, Gabriel L., Hannuna, Sion, Meakin, Lee B., Delisser, Peter J., Lanyon, Lance E., Price, Joanna S.
Publicado 2015

Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF,...

por Sunters, Andrew, Armstrong, Victoria J., Zaman, Gul, Kypta, Robert M., Kawano, Yoshiaki, Lanyon, Lance E., Price, Joanna S.
Publicado 2010

Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

por Galea, Gabriel L., Sunters, Andrew, Meakin, Lee B., Zaman, Gul, Sugiyama, Toshihiro, Lanyon, Lance E., Price, Joanna S.
Publicado 2011

Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor α and disuse

por Zaman, Gul, Saxon, Leanne K., Sunters, Andrew, Hilton, Helen, Underhill, Peter, Williams, Debbie, Price, Joanna S., Lanyon, Lance E.
Publicado 2010

Lrp5 Is Not Required for the Proliferative Response of Osteoblasts to Strain but Regulates Proliferation and Apoptosis in a Cell Autonomous Manner

por Javaheri, Behzad, Sunters, Andrew, Zaman, Gul, Suswillo, Rosemary F. L., Saxon, Leanne K., Lanyon, Lance E., Price, Joanna S.
Publicado 2012

Wnt16 Is Associated with Age-Related Bone Loss and Estrogen Withdrawal in Murine Bone

por Todd, Henry, Galea, Gabriel L., Meakin, Lee B., Delisser, Peter J., Lanyon, Lance E., Windahl, Sara H., Price, Joanna S.
Publicado 2015

Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle

por Galea, Gabriel L., Meakin, Lee B., Harris, Marie A., Delisser, Peter J., Lanyon, Lance E., Harris, Stephen E., Price, Joanna S.
Publicado 2017