Focal Adhesion Kinase Mediates the Integrin Signaling Requirement for Growth Factor Activation of Map Kinase

por Renshaw, Mark W., Price, Leo S., Schwartz, Martin Alexander
Publicado 1999

3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis

por Booij, Tijmen H., Price, Leo S., Danen, Erik H. J.
Publicado 2019

Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes

por Zhang, Yinghui, Moerkens, Marja, Ramaiahgari, Sreenivasa, de Bont, Hans, Price, Leo, Meerman, John, van de Water, Bob
Publicado 2011

Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the β(2)-adrenergic receptor

por Rangarajan, Savithri, Enserink, Jorrit M., Kuiperij, H. Bea, de Rooij, Johan, Price, Leo S., Schwede, Frank, Bos, Johannes L.
Publicado 2003

Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective

por Kanhai, Anish A., Bange, Hester, Verburg, Lotte, Dijkstra, Kyra L., Price, Leo S., Peters, Dorien J. M., Leonhard, Wouter N.
Publicado 2020

A 3D human co-culture to model neuron-astrocyte interactions in tauopathies

por Batenburg, Kevin L., Sestito, Claudia, Cornelissen-Steijger, Paulien, van Weering, Jan R. T., Price, Leo S., Heine, Vivi M., Scheper, Wiep
Publicado 2023

Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility

por Satomaa, Tero, Pynnönen, Henna, Vilkman, Anja, Kotiranta, Titta, Pitkänen, Virve, Heiskanen, Annamari, Herpers, Bram, Price, Leo S., Helin, Jari, Saarinen, Juhani
Publicado 2018

Development of a 3D Tissue Culture–Based High-Content Screening Platform That Uses Phenotypic Profiling to Discriminate Selective Inhibitors of Receptor Tyrosine Kinases

por Booij, Tijmen H., Klop, Maarten J. D., Yan, Kuan, Szántai-Kis, Csaba, Szokol, Balint, Orfi, Laszlo, van de Water, Bob, Keri, Gyorgy, Price, Leo S.
Publicado 2016

Ultra High Content Image Analysis and Phenotype Profiling of 3D Cultured Micro-Tissues

por Di, Zi, Klop, Maarten J. D., Rogkoti, Vasiliki-Maria, Le Dévédec, Sylvia E., van de Water, Bob, Verbeek, Fons J., Price, Leo S., Meerman, John H. N.
Publicado 2014

Prioritization of novel ADPKD drug candidates from disease-stage specific gene expression profiles

por Malas, Tareq B., Leonhard, Wouter N., Bange, Hester, Granchi, Zoraide, Hettne, Kristina M., Van Westen, Gerard J.P., Price, Leo S., 't Hoen, Peter A.C., Peters, Dorien J.M.
Publicado 2019

Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy

por Koedoot, Esmee, Wolters, Liesanne, Smid, Marcel, Stoilov, Peter, Burger, Gerhard A., Herpers, Bram, Yan, Kuan, Price, Leo S., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Publicado 2021

Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling

por Sandercock, Alan M., Rust, Steven, Guillard, Sandrine, Sachsenmeier, Kris F., Holoweckyj, Nick, Hay, Carl, Flynn, Matt, Huang, Qihui, Yan, Kuan, Herpers, Bram, Price, Leo S., Soden, Jo, Freeth, Jim, Jermutus, Lutz, Hollingsworth, Robert, Minter, Ralph
Publicado 2015

MEK inhibition induces apoptosis in osteosarcoma cells with constitutive ERK1/2 phosphorylation

por Baranski, Zuzanna, Booij, Tijmen H., Kuijjer, Marieke L., de Jong, Yvonne, Cleton-Jansen, Anne-Marie, Price, Leo S., van de Water, Bob, Bovée, Judith V. M. G., Hogendoorn, Pancras C.W., Danen, Erik H.J.
Publicado 2015

High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney Disease

por Booij, Tijmen H., Bange, Hester, Leonhard, Wouter N., Yan, Kuan, Fokkelman, Michiel, Kunnen, Steven J., Dauwerse, Johannes G., Qin, Yu, van de Water, Bob, van Westen, Gerard J. P., Peters, Dorien J. M., Price, Leo S.
Publicado 2017

In vitro 3D phenotypic drug screen identifies celastrol as an effective in vivo inhibitor of polycystic kidney disease

por Booij, Tijmen H, Leonhard, Wouter N, Bange, Hester, Yan, Kuan, Fokkelman, Michiel, Plugge, Anna J, Veraar, Kimberley A M, Dauwerse, Johannes G, van Westen, Gerard J P, van de Water, Bob, Price, Leo S, Peters, Dorien J M
Publicado 2019

3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors

por Badder, Luned M., Hollins, Andrew J., Herpers, Bram, Yan, Kuan, Ewan, Kenneth B., Thomas, Mairian, Shone, Jennifer R., Badder, Delyth A., Naven, Marc, Ashelford, Kevin E., Hargest, Rachel, Clarke, Alan R., Esdar, Christina, Buchstaller, Hans-Peter, Treherne, J. Mark, Boj, Sylvia, Ramezanpour, Bahar, Wienke, Dirk, Price, Leo S., Shaw, Paul H., Dale, Trevor C.
Publicado 2020