Lentiviral vectors containing mouse Csf1r control elements direct macrophage-restricted expression in multiple species of birds and mammals

por Pridans, Clare, Lillico, Simon, Whitelaw, Bruce, Hume, David A
Publicado 2014

The evolution of the macrophage-specific enhancer (Fms intronic regulatory element) within the CSF1R locus of vertebrates

por Hume, David A., Wollscheid-Lengeling, Evi, Rojo, Rocio, Pridans, Clare
Publicado 2017

CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function

por Pridans, Clare, Sauter, Kristin A., Baer, Kristin, Kissel, Holger, Hume, David A.
Publicado 2013

Cell origin and niche availability dictate the capacity of peritoneal macrophages to colonize the cavity and omentum

por Louwe, Pieter A., Forbes, Stuart J., Bénézech, Cécile, Pridans, Clare, Jenkins, Stephen J.
Publicado 2022

The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche

por Sehgal, Anuj, Donaldson, David S., Pridans, Clare, Sauter, Kristin A., Hume, David A., Mabbott, Neil A.
Publicado 2018

Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain

por Bradford, Barry M., McGuire, Lynne I., Hume, David A., Pridans, Clare, Mabbott, Neil A.
Publicado 2022

Transcriptomic Analysis of Rat Macrophages

por Pridans, Clare, Irvine, Katharine M., Davis, Gemma M., Lefevre, Lucas, Bush, Stephen J., Hume, David A.
Publicado 2021

Cloning and expression of feline colony stimulating factor receptor (CSF-1R) and analysis of the species specificity of stimulation by colony stimulating factor-1 (CSF-1) and inter...

por Gow, Deborah J., Garceau, Valerie, Pridans, Clare, Gow, Adam G., Simpson, Kerry E., Gunn-Moore, Danielle, Hume, David A.
Publicado 2013

Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development

por Munro, David AD, Wineberg, Yishay, Tarnick, Julia, Vink, Chris S, Li, Zhuan, Pridans, Clare, Dzierzak, Elaine, Kalisky, Tomer, Hohenstein, Peter, Davies, Jamie A
Publicado 2019

The Function of the Conserved Regulatory Element within the Second Intron of the Mammalian Csf1r Locus

por Sauter, Kristin A., Bouhlel, M. Amine, O’Neal, Julie, Sester, David P., Tagoh, Hiromi, Ingram, Richard M., Pridans, Clare, Bonifer, Constanze, Hume, David A.
Publicado 2013

CNS macrophages differentially rely on an intronic Csf1r enhancer for their development

por Munro, David A. D., Bradford, Barry M., Mariani, Samanta A., Hampton, David W., Vink, Chris S., Chandran, Siddharthan, Hume, David A., Pridans, Clare, Priller, Josef
Publicado 2020

Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations

por Patkar, Omkar L., Caruso, Melanie, Teakle, Ngari, Keshvari, Sahar, Bush, Stephen J., Pridans, Clare, Belmer, Arnauld, Summers, Kim M., Irvine, Katharine M., Hume, David A.
Publicado 2021

Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats

por Pridans, Clare, Sauter, Kristin A., Irvine, Katharine M., Davis, Gemma M., Lefevre, Lucas, Raper, Anna, Rojo, Rocio, Nirmal, Ajit J., Beard, Philippa, Cheeseman, Michael, Hume, David A.
Publicado 2018

CD11c identifies microbiota and EGR2‐dependent MHCII(+) serous cavity macrophages with sexually dimorphic fate in mice

por Bain, Calum C., Louwe, Pieter A., Steers, Nicholas J., Bravo‐Blas, Alberto, Hegarty, Lizi M., Pridans, Clare, Milling, Simon W.F., MacDonald, Andrew S., Rückerl, Dominik, Jenkins, Stephen J.
Publicado 2022

Species-Specificity of Transcriptional Regulation and the Response to Lipopolysaccharide in Mammalian Macrophages

por Bush, Stephen J., McCulloch, Mary E. B., Lisowski, Zofia M., Muriuki, Charity, Clark, Emily L., Young, Rachel, Pridans, Clare, Prendergast, James G. D., Summers, Kim M., Hume, David A.
Publicado 2020

Species-Specific Transcriptional Regulation of Genes Involved in Nitric Oxide Production and Arginine Metabolism in Macrophages

por Young, Rachel, Bush, Stephen J., Lefevre, Lucas, McCulloch, Mary E. B., Lisowski, Zofia M., Muriuki, Charity, Waddell, Lindsey A., Sauter, Kristin A., Pridans, Clare, Clark, Emily L., Hume, David A.
Publicado 2018

Pleiotropic effects of extended blockade of CSF1R signaling in adult mice

por Sauter, Kristin A., Pridans, Clare, Sehgal, Anuj, Tsai, Yi Ting, Bradford, Barry M., Raza, Sobia, Moffat, Lindsey, Gow, Deborah J., Beard, Philippa M., Mabbott, Neil A., Smith, Lee B., Hume, David A.
Publicado 2014

Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form

por Aarhus, Thomas Ihle, Bjørnstad, Frithjof, Wolowczyk, Camilla, Larsen, Kristin Uhlving, Rognstad, Line, Leithaug, Trygve, Unger, Anke, Habenberger, Peter, Wolf, Alexander, Bjørkøy, Geir, Pridans, Clare, Eickhoff, Jan, Klebl, Bert, Hoff, Bård H., Sundby, Eirik
Publicado 2023

A Csf1r-EGFP Transgene Provides a Novel Marker for Monocyte Subsets in Sheep

por Pridans, Clare, Davis, Gemma M., Sauter, Kristin A., Lisowski, Zofia M., Corripio-Miyar, Yolanda, Raper, Anna, Lefevre, Lucas, Young, Rachel, McCulloch, Mary E., Lillico, Simon, Milne, Elspeth, Whitelaw, Bruce, Hume, David A.
Publicado 2016

A chicken bioreactor for efficient production of functional cytokines

por Herron, Lissa R., Pridans, Clare, Turnbull, Matthew L., Smith, Nikki, Lillico, Simon, Sherman, Adrian, Gilhooley, Hazel J., Wear, Martin, Kurian, Dominic, Papadakos, Grigorios, Digard, Paul, Hume, David A., Gill, Andrew C., Sang, Helen M.
Publicado 2018