Comment on “Hypercholesterolemia with consumption of PFOA-laced Western diets is dependent on strain and sex of mice” by Rebholz S.L. et al. Toxicol. Rep. 2016 (3) 46–54

por Princen, Hans M.G., Pouwer, Marianne G., Pieterman, Elsbet J.
Publicado 2016

Anti-PCSK9 antibodies inhibit pro-atherogenic mechanisms in APOE*3Leiden.CETP mice

por Schuster, Susanne, Rubil, Sandra, Endres, Matthias, Princen, Hans M. G., Boeckel, Jes-Niels, Winter, Karsten, Werner, Christian, Laufs, Ulrich
Publicado 2019

Beneficial effects of elafibranor on NASH in E3L.CETP mice and differences between mice and men

por van den Hoek, Anita M., Verschuren, Lars, Caspers, Martien P. M., Worms, Nicole, Menke, Aswin L., Princen, Hans M. G.
Publicado 2021

Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice

por Pouwer, Marianne G., Pieterman, Elsbet J., Worms, Nicole, Keijzer, Nanda, Jukema, J. Wouter, Gromada, Jesper, Gusarova, Viktoria, Princen, Hans M. G.
Publicado 2020

Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice

por van Keulen, Danielle, Pouwer, Marianne G., Pasterkamp, Gerard, van Gool, Alain J., Sollewijn Gelpke, Maarten D., Princen, Hans M. G., Tempel, Dennie
Publicado 2018

Dose Effects of Ammonium Perfluorooctanoate on Lipoprotein Metabolism in APOE*3-Leiden.CETP Mice

por Pouwer, Marianne G, Pieterman, Elsbet J, Chang, Shu-Ching, Olsen, Geary W, Caspers, Martien P M, Verschuren, Lars, Jukema, J Wouter, Princen, Hans M G
Publicado 2019

The BCR-ABL1 Inhibitors Imatinib and Ponatinib Decrease Plasma Cholesterol and Atherosclerosis, and Nilotinib and Ponatinib Activate Coagulation in a Translational Mouse Model

por Pouwer, Marianne G., Pieterman, Elsbet J., Verschuren, Lars, Caspers, Martien P. M., Kluft, Cornelis, Garcia, Ricardo A., Aman, Jurjan, Jukema, J. Wouter, Princen, Hans M. G.
Publicado 2018

The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden.CETP mice

por Landlinger, Christine, Pouwer, Marianne G., Juno, Claudia, van der Hoorn, José W.A., Pieterman, Elsbet J., Jukema, J. Wouter, Staffler, Guenther, Princen, Hans M.G., Galabova, Gergana
Publicado 2017

Chronic Oral Administration of Mineral Oil Compared With Corn Oil: Effects on Gut Permeability and Plasma Inflammatory and Lipid Biomarkers

por Pieterman, Elsbet J., Princen, Hans M. G., Jarke, Annica, Nilsson, Ralf, Cavallin, Anders, Bergenholm, Linnéa, Henricsson, Marcus, Gopaul, V. Sashi, Agrawal, Rahul, Nissen, Steven E., Hurt-Camejo, Eva
Publicado 2021

Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice

por van den Hoek, Anita M., Pieterman, Elsbet J., van der Hoorn, José W., Iruarrizaga‐Lejarreta, Marta, Alonso, Cristina, Verschuren, Lars, Skjæret, Tore, Princen, Hans M.G., Fraser, David A.
Publicado 2019

Both Transient and Continuous Corticosterone Excess Inhibit Atherosclerotic Plaque Formation in APOE*3-Leiden.CETP Mice

por Auvinen, Hanna E., Wang, Yanan, Princen, Hans, Romijn, Johannes A., Havekes, Louis M., Smit, Johannes W. A., Meijer, Onno C., Biermasz, Nienke R., Rensen, Patrick C. N., Pereira, Alberto M.
Publicado 2013

The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis

por Carracedo, Miguel, Pawelzik, Sven‐Christian, Artiach, Gonzalo, Pouwer, Marianne G., Plunde, Oscar, Saliba‐Gustafsson, Peter, Ehrenborg, Ewa, Eriksson, Per, Pieterman, Elsbet, Stenke, Leif, Princen, Hans M. G., Franco‐Cereceda, Anders, Bäck, Magnus
Publicado 2022

Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans

por van Keulen, Danielle, van Koeverden, Ian D., Boltjes, Arjan, Princen, Hans M. G., van Gool, Alain J., de Borst, Gert J., Asselbergs, Folkert W., Tempel, Dennie, Pasterkamp, Gerard, van der Laan, Sander W.
Publicado 2021

Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation

por Inia, José A., Stokman, Geurt, Pieterman, Elsbet J., Morrison, Martine C., Menke, Aswin L., Verschuren, Lars, Caspers, Martien P. M., Giera, Martin, Jukema, J. Wouter, van den Hoek, Anita M., Princen, Hans M. G.
Publicado 2023

Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin

por Kühnast, Susan, van der Hoorn, José W. A., Pieterman, Elsbet J., van den Hoek, Anita M., Sasiela, William J., Gusarova, Viktoria, Peyman, Anusch, Schäfer, Hans-Ludwig, Schwahn, Uwe, Jukema, J. Wouter, Princen, Hans M. G.
Publicado 2014

Semaglutide Has Beneficial Effects on Non-Alcoholic Steatohepatitis in Ldlr-/-.Leiden Mice

por Inia, José A., Stokman, Geurt, Morrison, Martine C., Worms, Nicole, Verschuren, Lars, Caspers, Martien P. M., Menke, Aswin L., Petitjean, Louis, Chen, Li, Petitjean, Mathieu, Jukema, J. Wouter, Princen, Hans M. G., van den Hoek, Anita M.
Publicado 2023

The APOE(∗)3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis

por Pouwer, Marianne G., Heinonen, Suvi E., Behrendt, Margareta, Andréasson, Anne-Christine, van Koppen, Arianne, Menke, Aswin L., Pieterman, Elsbet J., van den Hoek, Anita M., Jukema, J. Wouter, Leighton, Brendan, Jönsson-Rylander, Ann-Cathrine, Princen, Hans M. G.
Publicado 2019

In Vivo Magnetic Resonance Imaging‐Based Detection of Heterogeneous Endothelial Response in Thoracic and Abdominal Aorta to Short‐Term High‐Fat Diet Ascribed to Differences in Peri...

por Bar, Anna, Kieronska‐Rudek, Anna, Proniewski, Bartosz, Suraj‐Prażmowska, Joanna, Czamara, Krzysztof, Marczyk, Brygida, Matyjaszczyk‐Gwarda, Karolina, Jasztal, Agnieszka, Kuś, Edyta, Majka, Zuzanna, Kaczor, Agnieszka, Kurpińska, Anna, Walczak, Maria, Pieterman, Elsbet J., Princen, Hans M. G., Chlopicki, Stefan
Publicado 2020

A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo

por Suchowerska, Alexandra K., Stokman, Geurt, Palmer, James T., Coghlan, Phillip A., Pieterman, Elsbet J., Keijzer, Nanda, Lambert, Gilles, Chemello, Kevin, Jaafar, Ali K., Parmar, Jasneet, Yan, Liping, Tong, Yingtao, Mu, Lin, Princen, Hans M.G., Bonnar, James, Evison, Benny J.
Publicado 2022

Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model

por Zancanella, Vanessa, Vallès, Astrid, Liefhebber, Jolanda M.P., Paerels, Lieke, Tornero, Carlos Vendrell, Wattimury, Hendrina, van der Zon, Tom, van Rooijen, Kristel, Golinska, Monika, Grevelink, Tamar, Ehlert, Erich, Pieterman, Elsbet Jantine, Keijzer, Nanda, Princen, Hans Marinus Gerardus, Stokman, Geurt, Liu, Ying Poi
Publicado 2023