Treating Alzheimer’s disease with monoclonal antibodies: current status and outlook for the future

por Prins, Niels D, Scheltens, Philip
Publicado 2013

Can novel therapeutics halt the amyloid cascade?

por Prins, Niels D, Visser, Pieter Jelle, Scheltens, Philip
Publicado 2010

Amyloid imaging in prodromal Alzheimer's disease

por Ossenkoppele, Rik, van Berckel, Bart NM, Prins, Niels D
Publicado 2011

Amyloid imaging in clinical trials

por Ossenkoppele, Rik, Prins, Niels D, van Berckel, Bart NM
Publicado 2013

The effect of diagnostic criteria on outcome measures in preclinical and prodromal Alzheimer's disease: Implications for trial design

por Bertens, Daniela, Tijms, Betty M., Vermunt, Lisa, Prins, Niels D., Scheltens, Philip, Visser, Pieter Jelle
Publicado 2017

A phase 2 double-blind placebo-controlled 24-week treatment clinical study of the p38 alpha kinase inhibitor neflamapimod in mild Alzheimer’s disease

por Prins, Niels D., Harrison, John E., Chu, Hui-May, Blackburn, Kelly, Alam, John J., Scheltens, Philip
Publicado 2021

Microbleeds are associated with depressive symptoms in Alzheimer's disease

por Leeuwis, Anna E., Prins, Niels D., Hooghiemstra, Astrid M., Benedictus, Marije R., Scheltens, Philip, Barkhof, Frederik, van der Flier, Wiesje M.
Publicado 2017

Lower cerebral blood flow in subjects with Alzheimer's dementia, mild cognitive impairment, and subjective cognitive decline using two-dimensional phase-contrast magnetic resonance...

por Leijenaar, Jolien F., van Maurik, Ingrid S., Kuijer, Joost P.A., van der Flier, Wiesje M., Scheltens, Philip, Barkhof, Frederik, Prins, Niels D.
Publicado 2017

The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized con...

por Prins, Niels D, van der Flier, Wiesje A, Knol, Dirk L, Fox, Nick C, Brashear, H Robert, Nye, Jeffrey S, Barkhof, Frederik, Scheltens, Philip
Publicado 2014

An exploratory clinical study of p38α kinase inhibition in Alzheimer's disease

por Scheltens, Philip, Prins, Niels, Lammertsma, Adriaan, Yaqub, Maqsood, Gouw, Alida, Wink, Alle Meije, Chu, Hui‐May, van Berckel, Bart N. M., Alam, John
Publicado 2018

Experiences of and recommendations on clinical trial design in Alzheimer’s disease from the participant’s point of view: a mixed-methods study in two clinical trial centers in the...

por Ottenhoff, Lois, Vijverberg, Everard G. B., Visser, Leonie N. C., Verijp, Merike, Prins, Niels D., Van der Flier, Wiesje M., Sikkes, Sietske A. M.
Publicado 2023

Lower cerebral blood flow is associated with faster cognitive decline in Alzheimer’s disease

por Benedictus, Marije R., Leeuwis, Annebet E., Binnewijzend, Maja A.A., Kuijer, Joost P.A., Scheltens, Philip, Barkhof, Frederik, van der Flier, Wiesje M., Prins, Niels D.
Publicado 2016

Symptomatic Treatment of Vascular Cognitive Impairment (STREAM-VCI): Protocol for a Cross-Over Trial

por Leijenaar, Jolien Fleur, Groeneveld, Geert Jan, van der Flier, Wiesje Maria, Scheltens, Philip, Klaassen, Erica Surya, Weinstein, Henry Chanoch, Biessels, Geert Jan, Barkhof, Frederik, Prins, Niels Daniël
Publicado 2018

Survival in memory clinic cohort is short, even in young-onset dementia

por Rhodius-Meester, Hanneke Frederica Maria, Tijms, Betty M, Lemstra, Afina W, Prins, Niels D, Pijnenburg, Yolande A L, Bouwman, Femke, Scheltens, Philip, van der Flier, Wiesje M
Publicado 2019

Schizophrenia as a mimic of behavioral variant frontotemporal dementia

por Kerssens, Cora J., Krudop, Welmoed A., Prins, Niels D., van Berckel, Bart N. M., Rozemuller, Annemieke, Seeley, William W., Scheltens, Philip, Stek, Max L., Pijnenburg, Yolande A. L.
Publicado 2016

Screening for Mild Cognitive Impairment and Dementia with Automated, Anonymous Online and Telephone Cognitive Self-Tests

por Van Mierlo, Lisa D., Wouters, Hans, Sikkes, Sietske A.M., Van der Flier, Wiesje M., Prins, Niels D., Bremer, Jonne A.E., Koene, Teddy, Van Hout, Hein P.J.
Publicado 2017

Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset

por Heinen, Rutger, Steenwijk, Martijn D., Barkhof, Frederik, Biesbroek, J. Matthijs, van der Flier, Wiesje M., Kuijf, Hugo J., Prins, Niels D., Vrenken, Hugo, Biessels, Geert Jan, de Bresser, Jeroen
Publicado 2019

Small vessel disease lesion type and brain atrophy: The role of co‐occurring amyloid

por Heinen, Rutger, Groeneveld, Onno N., Barkhof, Frederik, de Bresser, Jeroen, Exalto, Lieza G., Kuijf, Hugo J., Prins, Niels D., Scheltens, Philip, van der Flier, Wiesje M., Biessels, Geert Jan
Publicado 2020

A more randomly organized grey matter network is associated with deteriorating language and global cognition in individuals with subjective cognitive decline

por Verfaillie, Sander C. J., Slot, Rosalinde E. R., Dicks, Ellen, Prins, Niels D., Overbeek, Jozefien M., Teunissen, Charlotte E., Scheltens, Philip, Barkhof, Frederik, van der Flier, Wiesje M., Tijms, Betty M.
Publicado 2018

Plasma Amyloid as Prescreener for the Earliest Alzheimer Pathological Changes

por Verberk, Inge M. W., Slot, Rosalinde E., Verfaillie, Sander C. J., Heijst, Hans, Prins, Niels D., van Berckel, Bart N. M., Scheltens, Philip, Teunissen, Charlotte E., van der Flier, Wiesje M.
Publicado 2018