Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes

por Zhao, Boyang, Pritchard, Justin R.
Publicado 2016

Evolution of the nonsense-mediated decay pathway is associated with decreased cytolytic immune infiltration

por Zhao, Boyang, Pritchard, Justin R.
Publicado 2019

The risks of perpetuating an evolutionary arms race in drug discovery

por Leighow, Scott M, Pritchard, Justin R
Publicado 2019

Refined Quantification of Infection Bottlenecks and Pathogen Dissemination with STAMPR

por Hullahalli, Karthik, Pritchard, Justin R., Waldor, Matthew K.
Publicado 2021

The role of migration in mutant dynamics in fragmented populations

por Kreger, Jesse, Brown, Donovan, Komarova, Natalia L., Wodarz, Dominik, Pritchard, Justin
Publicado 2022

Disruption of Mycobacterium avium subsp. paratuberculosis-specific genes impairs in vivo fitness

por Wang, Joyce, Pritchard, Justin R, Kreitmann, Louis, Montpetit, Alexandre, Behr, Marcel A
Publicado 2014

Multi-scale Predictions of Drug Resistance Epidemiology Identify Design Principles for Rational Drug Design

por Leighow, Scott M., Liu, Chuan, Inam, Haider, Zhao, Boyang, Pritchard, Justin R.
Publicado 2020

A global cancer data integrator reveals principles of synthetic lethality, sex disparity and immunotherapy

por Yogodzinski, Christopher, Arab, Abolfazl, Pritchard, Justin R., Goodarzi, Hani, Gilbert, Luke A.
Publicado 2021

Acquisition of a single EZH2 D1 domain mutation confers acquired resistance to EZH2-targeted inhibitors

por Baker, Theresa, Nerle, Sujata, Pritchard, Justin, Zhao, Boyang, Rivera, Victor M., Garner, Andrew, Gonzalvez, Francois
Publicado 2015

A pan-CRISPR analysis of mammalian cell specificity identifies ultra-compact sgRNA subsets for genome-scale experiments

por Zhao, Boyang, Rao, Yiyun, Leighow, Scott, O’Brien, Edward P., Gilbert, Luke, Pritchard, Justin R.
Publicado 2022

High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model–based analyses of transposon-insertion sequencing data

por Chao, Michael C., Pritchard, Justin R., Zhang, Yanjia J., Rubin, Eric J., Livny, Jonathan, Davis, Brigid M., Waldor, Matthew K.
Publicado 2013

ARTIST: High-Resolution Genome-Wide Assessment of Fitness Using Transposon-Insertion Sequencing

por Pritchard, Justin R., Chao, Michael C., Abel, Sören, Davis, Brigid M., Baranowski, Catherine, Zhang, Yanjia J., Rubin, Eric J., Waldor, Matthew K.
Publicado 2014

Genomic and experimental evidence that ALK(ATI) does not predict single agent sensitivity to ALK inhibitors

por Inam, Haider, Sokirniy, Ivan, Rao, Yiyun, Shah, Anushka, Naeemikia, Farnaz, O'Brien, Edward, Dong, Cheng, McCandlish, David M., Pritchard, Justin R.
Publicado 2021

How soluble misfolded proteins bypass chaperones at the molecular level

por Halder, Ritaban, Nissley, Daniel A., Sitarik, Ian, Jiang, Yang, Rao, Yiyun, Vu, Quyen V., Li, Mai Suan, Pritchard, Justin, O’Brien, Edward P.
Publicado 2023

RET fusions observed in lung and colorectal cancers are sensitive to ponatinib

por Gozgit, Joseph M., Chen, Tzu-Hsiu, Song, Youngchul, Wardwell, Scott, Wang, Frank, Cai, Jie, Li, Henry, Edgren, Henrik, Rivera, Victor M., Pritchard, Justin
Publicado 2018

A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth

por Meacham, Corbin E., Lawton, Lee N., Soto-Feliciano, Yadira M., Pritchard, Justin R., Joughin, Brian A., Ehrenberger, Tobias, Fenouille, Nina, Zuber, Johannes, Williams, Richard T., Young, Richard A., Hemann, Michael T.
Publicado 2015

Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers

por George, Suzanne, von Mehren, Margaret, Fletcher, Jonathan A., Sun, Jichao, Zhang, Sen, Pritchard, Justin R., Hodgson, John Graeme, Kerstein, David, Rivera, Victor M., Haluska, Frank G., Heinrich, Michael C.
Publicado 2022

Excessive concentrations of kinase inhibitors in translational studies impede effective drug repurposing

por Liu, Chuan, Leighow, Scott M., McIlroy, Kyle, Lu, Mengrou, Dennis, Kady A., Abello, Kerry, Brown, Donovan J., Moore, Connor J., Shah, Anushka, Inam, Haider, Rivera, Victor M., Pritchard, Justin R.
Publicado 2023

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

por Rock, Jeremy M., Hopkins, Forrest F., Chavez, Alejandro, Diallo, Marieme, Chase, Michael R., Gerrick, Elias R., Pritchard, Justin R., Church, George M., Rubin, Eric J., Sassetti, Christopher M., Schnappinger, Dirk, Fortune, Sarah M.
Publicado 2017

Optimal SARS-CoV-2 vaccine allocation using real-time seroprevalence estimates in Rhode Island and Massachusetts

por Tran, Thu Nguyen-Anh, Wikle, Nathan, Albert, Joseph, Inam, Haider, Strong, Emily, Brinda, Karel, Leighow, Scott M, Yang, Fuhan, Hossain, Sajid, Pritchard, Justin R, Chan, Philip, Hanage, William P, Hanks, Ephraim M, Boni, Maciej F
Publicado 2021