A scalable workflow to test “shock and kill” therapeutic approaches against the HIV-1 latent reservoir in blood cells ex vivo

por Procopio, Francesco Andrea, Savarino, Andrea, Shytaj, Iart Luca
Publicado 2023

In Vitro Reactivation of Replication-Competent and Infectious HIV-1 by Histone Deacetylase Inhibitors

por Banga, Riddhima, Procopio, Francesco Andrea, Cavassini, Matthias, Perreau, Matthieu
Publicado 2016

Inducible HIV-1 Reservoir Quantification: Clinical Relevance, Applications and Advancements of TILDA

por Lungu, Cynthia, Banga, Riddhima, Gruters, Rob A., Procopio, Francesco A.
Publicado 2021

Characterization of Transcription Factor Phenotypes within Antigen-Specific CD4+ T Cells Using Qualitative Multiplex Single-Cell RT-PCR

por Phetsouphanh, Chansavath, Xu, Yin, Amin, Janaki, Seddiki, Nabila, Procopio, Francesco, Sekaly, Rafick Pierre, Zaunders, John J., Kelleher, Anthony D.
Publicado 2013

Blood CXCR3(+) CD4 T Cells Are Enriched in Inducible Replication Competent HIV in Aviremic Antiretroviral Therapy-Treated Individuals

por Banga, Riddhima, Procopio, Francesco A., Ruggiero, Alessandra, Noto, Alessandra, Ohmiti, Khalid, Cavassini, Matthias, Corpataux, Jean-Marc, Paxton, William A., Pollakis, Georgios, Perreau, Matthieu
Publicado 2018

CD32(+) and PD-1(+) Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals

por Noto, Alessandra, Procopio, Francesco A., Banga, Riddhima, Suffiotti, Madeleine, Corpataux, Jean-Marc, Cavassini, Matthias, Riva, Agostino, Fenwick, Craig, Gottardo, Raphael, Perreau, Matthieu, Pantaleo, Giuseppe
Publicado 2018

Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells

por Munoz, Olivia, Banga, Riddhima, Schelling, Rachel, Procopio, Francesco Andrea, Mastrangelo, Andrea, Nortier, Pauline, Ohmiti, Khalid, Daraspe, Jean, Cavassini, Matthias, Fenwick, Craig, Perez, Laurent, Perreau, Matthieu
Publicado 2022

HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses

por Zhang, Yuwei, El-Far, Mohamed, Dupuy, Franck P., Abdel-Hakeem, Mohamed S., He, Zhong, Procopio, Francesco Andrea, Shi, Yu, Haddad, Elias K., Ancuta, Petronela, Sekaly, Rafick-Pierre, Said, Elias A.
Publicado 2016

Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement

por Banga, Riddhima, Rebecchini, Caterina, Procopio, Francesco Andrea, Noto, Alessandra, Munoz, Olivia, Ioannidou, Kalliopi, Fenwick, Craig, Ohmiti, Khalid, Cavassini, Matthias, Corpataux, Jean-Marc, de Leval, Laurence, Pantaleo, Giuseppe, Perreau, Matthieu
Publicado 2019

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4(+) T cells from ART-suppressed individuals

por Fromentin, Rémi, DaFonseca, Sandrina, Costiniuk, Cecilia T., El-Far, Mohamed, Procopio, Francesco Andrea, Hecht, Frederick M., Hoh, Rebecca, Deeks, Steven G., Hazuda, Daria J., Lewin, Sharon R., Routy, Jean-Pierre, Sékaly, Rafick-Pierre, Chomont, Nicolas
Publicado 2019

Myeloid Dendritic Cells Induce HIV-1 Latency in Non-proliferating CD4(+) T Cells

por Evans, Vanessa A., Kumar, Nitasha, Filali, Ali, Procopio, Francesco A., Yegorov, Oleg, Goulet, Jean-Philippe, Saleh, Suha, Haddad, Elias K., da Fonseca Pereira, Candida, Ellenberg, Paula C., Sekaly, Rafick-Pierre, Cameron, Paul U., Lewin, Sharon R.
Publicado 2013

The deficiency in Th2-like Tfh cells affects the maturation and quality of HIV-specific B cell response in viremic infection

por Noto, Alessandra, Suffiotti, Madeleine, Joo, Victor, Mancarella, Antonio, Procopio, Francesco A., Cavet, Guy, Leung, Yvonne, Corpataux, Jean-Marc, Cavassini, Matthias, Riva, Agostino, Stamatatos, Leonidas, Gottardo, Raphael, McDermott, Adrian B., Koup, Richard A., Fenwick, Craig, Perreau, Matthieu, Pantaleo, Giuseppe
Publicado 2022

Inter-Laboratory Reproducibility of Inducible HIV-1 Reservoir Quantification by TILDA

por Lungu, Cynthia, Procopio, Francesco A., Overmars, Ronald J., Beerkens, Rob J. J., Voermans, Jolanda J. C., Rao, Shringar, Prins, Henrieke A. B., Rokx, Casper, Pantaleo, Giuseppe, van de Vijver, David A. M. C., Mahmoudi, Tokameh, Boucher, Charles A. B., Gruters, Rob A., van Kampen, Jeroen J. A.
Publicado 2020

A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals

por Procopio, Francesco Andrea, Fromentin, Rémi, Kulpa, Deanna A., Brehm, Jessica H., Bebin, Anne-Gaelle, Strain, Matthew C., Richman, Douglas D., O'Doherty, Una, Palmer, Sarah, Hecht, Frederick M., Hoh, Rebecca, Barnard, Richard J.O., Miller, Michael D., Hazuda, Daria J., Deeks, Steven G., Sékaly, Rafick-Pierre, Chomont, Nicolas
Publicado 2015

Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs

por Said, Elias A., Al-Dughaishi, Sumaya, Al-Hatmi, Wadha, Al-Reesi, Iman, Al-Balushi, Mohammed S., Al-Bimani, Atika, Al-Busaidi, Juma Z., Al-Riyami, Marwa, Al-Khabori, Murtadha, Al-Kindi, Salam, Procopio, Francesco A., Al-Sinawi, Shadia, Al-Ansari, Aliyaa, Koh, Crystal Y., Al-Naamani, Khalid, Al-Jabri, Ali A.
Publicado 2023

Human macrophages and monocyte-derived dendritic cells stimulate the proliferation of endothelial cells through midkine production

por Said, Elias A., Al-Dughaishi, Sumaya, Al-Hatmi, Wadha, Al-Reesi, Iman, Al-Riyami, Marwa, Al-Balushi, Mohammed S., Al-Bimani, Atika, Al-Busaidi, Juma Z., Al-Khabori, Murtadha, Al-Kindi, Salam, Procopio, Francesco A., Al-Rashdi, Afrah, Al-Ansari, Aliyaa, Babiker, Hamza, Koh, Crystal Y., Al-Naamani, Khalid, Pantaleo, Giuseppe, Al-Jabri, Ali A.
Publicado 2022

Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress

por Shytaj, Iart Luca, Procopio, Francesco Andrea, Tarek, Mohammad, Carlon‐Andres, Irene, Tang, Hsin‐Yao, Goldman, Aaron R, Munshi, MohamedHusen, Kumar Pal, Virender, Forcato, Mattia, Sreeram, Sheetal, Leskov, Konstantin, Ye, Fengchun, Lucic, Bojana, Cruz, Nicolly, Ndhlovu, Lishomwa C, Bicciato, Silvio, Padilla‐Parra, Sergi, Diaz, Ricardo Sobhie, Singh, Amit, Lusic, Marina, Karn, Jonathan, Alvarez‐Carbonell, David, Savarino, Andrea
Publicado 2021

Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy

por Elliott, Julian H., Wightman, Fiona, Solomon, Ajantha, Ghneim, Khader, Ahlers, Jeffrey, Cameron, Mark J., Smith, Miranda Z., Spelman, Tim, McMahon, James, Velayudham, Pushparaj, Brown, Gregor, Roney, Janine, Watson, Jo, Prince, Miles H., Hoy, Jennifer F., Chomont, Nicolas, Fromentin, Rémi, Procopio, Francesco A., Zeidan, Joumana, Palmer, Sarah, Odevall, Lina, Johnstone, Ricky W., Martin, Ben P., Sinclair, Elizabeth, Deeks, Steven G., Hazuda, Daria J., Cameron, Paul U., Sékaly, Rafick-Pierre, Lewin, Sharon R.
Publicado 2014