Simplifying complexity: genetically resculpting glycosphingolipid synthesis pathways in mice to reveal function

por Allende, Maria Laura, Proia, Richard L.
Publicado 2014

A perilous path: the inborn errors of sphingolipid metabolism

por Dunn, Teresa M., Tifft, Cynthia J., Proia, Richard L.
Publicado 2019

Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit

por Lo, Charles G., Xu, Ying, Proia, Richard L., Cyster, Jason G.
Publicado 2005

S1P(4) Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells

por Kulinski, Joseph M., Proia, Richard L., Larson, Elisabeth M., Metcalfe, Dean D., Olivera, Ana
Publicado 2018

Bioluminescence imaging of G protein-coupled receptor activation in living mice

por Kono, Mari, Conlon, Elizabeth G., Lux, Samantha Y., Yanagida, Keisuke, Hla, Timothy, Proia, Richard L.
Publicado 2017

The Complement Regulator Susd4 Influences Nervous-System Function and Neuronal Morphology in Mice

por Zhu, Hongling, Meissner, Laura E., Byrnes, Colleen, Tuymetova, Galina, Tifft, Cynthia J., Proia, Richard L.
Publicado 2020

S1P(1) receptor overrides regulatory T cell-mediated immune suppression through Akt-mTOR

por Liu, Guangwei, Burns, Samir, Huang, Gonghua, Boyd, Kelli, Proia, Richard L., Flavell, Richard A., Chi, Hongbo
Publicado 2009

S1P1 receptor directs the release of immature B cells from bone marrow into blood

por Allende, Maria L., Tuymetova, Galina, Lee, Bridgin G., Bonifacino, Eliana, Wu, Yun-Ping, Proia, Richard L.
Publicado 2010

A genome-wide CRISPR/Cas9 screen reveals that the aryl hydrocarbon receptor stimulates sphingolipid levels

por Majumder, Saurav, Kono, Mari, Lee, Y. Terry, Byrnes, Colleen, Li, Cuiling, Tuymetova, Galina, Proia, Richard L.
Publicado 2020

Identification of two lipid phosphatases that regulate sphingosine-1-phosphate cellular uptake and recycling

por Kono, Mari, Hoachlander-Hobby, Lila E., Majumder, Saurav, Schwartz, Ronit, Byrnes, Colleen, Zhu, Hongling, Proia, Richard L.
Publicado 2022

Transactivation of Sphingosine-1–Phosphate Receptors by FcɛRI Triggering Is Required for Normal Mast Cell Degranulation and Chemotaxis

por Jolly, Puneet S., Bektas, Meryem, Olivera, Ana, Gonzalez-Espinosa, Claudia, Proia, Richard L., Rivera, Juan, Milstien, Sheldon, Spiegel, Sarah
Publicado 2004

Ablation of PPARγ in subcutaneous fat exacerbates age‐associated obesity and metabolic decline

por Xu, Lingyan, Ma, Xinran, Verma, Narendra Kumar, Wang, Dongmei, Gavrilova, Oksana, Proia, Richard L., Finkel, Toren, Mueller, Elisabetta
Publicado 2018

Opposing Roles of S1P(3) Receptors in Myocardial Function

por Wafa, Dina, Koch, Nóra, Kovács, Janka, Kerék, Margit, Proia, Richard L., Tigyi, Gábor J., Benyó, Zoltán, Miklós, Zsuzsanna
Publicado 2020

Plasma cell S1P(1) expression determines secondary lymphoid organ retention versus bone marrow tropism

por Kabashima, Kenji, Haynes, Nicole M., Xu, Ying, Nutt, Stephen L., Allende, Maria L., Proia, Richard L., Cyster, Jason G.
Publicado 2006

Activated platelets release sphingosine 1-phosphate and induce hypersensitivity to noxious heat stimuli in vivo

por Weth, Daniela, Benetti, Camilla, Rauch, Caroline, Gstraunthaler, Gerhard, Schmidt, Helmut, Geisslinger, Gerd, Sabbadini, Roger, Proia, Richard L., Kress, Michaela
Publicado 2015

Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice

por Li, Wenmei, Sandhoff, Roger, Kono, Mari, Zerfas, Patricia, Hoffmann, Vickie, Ding, Bryan Char-Hoa, Proia, Richard L., Deng, Chu-Xia
Publicado 2007

Sphingosine-1-Phosphate and the S1P(3) Receptor Initiate Neuronal Retraction via RhoA/ROCK Associated with CRMP2 Phosphorylation

por Quarta, Serena, Camprubí-Robles, Maria, Schweigreiter, Rüdiger, Matusica, Dusan, Haberberger, Rainer V., Proia, Richard L., Bandtlow, Christine E., Ferrer-Montiel, Antonio, Kress, Michaela
Publicado 2017

Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation

por Ishimaru, Kazuhiro, Yoshioka, Kazuaki, Kano, Kuniyuki, Kurano, Makoto, Saigusa, Daisuke, Aoki, Junken, Yatomi, Yutaka, Takuwa, Noriko, Okamoto, Yasuo, Proia, Richard L., Takuwa, Yoh
Publicado 2019

HDL-bound sphingosine 1-phosphate restrains lymphopoiesis and neuroinflammation

por Blaho, Victoria A., Galvani, Sylvain, Engelbrecht, Eric, Liu, Catherine, Swendeman, Steven L., Kono, Mari, Proia, Richard L., Steinman, Lawrence, Han, May H., Hla, Timothy
Publicado 2015

Human GLB1 knockout cerebral organoids: A model system for testing AAV9-mediated GLB1 gene therapy for reducing GM1 ganglioside storage in GM1 gangliosidosis

por Latour, Yvonne L., Yoon, Robin, Thomas, Sarah E., Grant, Christina, Li, Cuiling, Sena-Esteves, Miguel, Allende, Maria L., Proia, Richard L., Tifft, Cynthia J.
Publicado 2019