Tunable Heteroaromatic Nitriles for Selective Bioorthogonal Click Reaction with Cysteine

por Proj, Matic, Strašek, Nika, Pajk, Stane, Knez, Damijan, Sosič, Izidor
Publicado 2023

Towards discovery of inhibitors of the undecaprenyl-pyrophosphate phosphatase BacA by virtual high-throughput screening

por Jukič, Marko, Auger, Rodolphe, Folcher, Victor, Proj, Matic, Barreteau, Hélène, Gobec, Stanislav, Touzé, Thierry
Publicado 2022

Discovery of compounds with viscosity-reducing effects on biopharmaceutical formulations with monoclonal antibodies

por Proj, Matic, Zidar, Mitja, Lebar, Blaž, Strašek, Nika, Miličić, Goran, Žula, Aleš, Gobec, Stanislav
Publicado 2022

Discovery of a fragment hit compound targeting D-Ala:D-Ala ligase of bacterial peptidoglycan biosynthesis

por Proj, Matic, Hrast, Martina, Bajc, Gregor, Frlan, Rok, Meden, Anže, Butala, Matej, Gobec, Stanislav
Publicado 2022

Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?

por Proj, Matic, Hrast, Martina, Knez, Damijan, Bozovičar, Krištof, Grabrijan, Katarina, Meden, Anže, Gobec, Stanislav, Frlan, Rok
Publicado 2022

Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors

por Schiffrer, Eva Shannon, Proj, Matic, Gobec, Martina, Rejc, Luka, Šterman, Andrej, Mravljak, Janez, Gobec, Stanislav, Sosič, Izidor
Publicado 2021

Discovery of Immunoproteasome Inhibitors Using Large-Scale Covalent Virtual Screening

por Scarpino, Andrea, Bajusz, Dávid, Proj, Matic, Gobec, Martina, Sosič, Izidor, Gobec, Stanislav, Ferenczy, György G., Keserű, György M.
Publicado 2019

New inhibitors of cathepsin V impair tumor cell proliferation and elastin degradation and increase immune cell cytotoxicity

por Mitrović, Ana, Senjor, Emanuela, Jukić, Marko, Bolčina, Lara, Prunk, Mateja, Proj, Matic, Nanut, Milica Perišić, Gobec, Stanislav, Kos, Janko
Publicado 2022

A Set of Experimentally Validated Decoys for the Human CC Chemokine Receptor 7 (CCR7) Obtained by Virtual Screening

por Proj, Matic, De Jonghe, Steven, Van Loy, Tom, Jukič, Marko, Meden, Anže, Ciber, Luka, Podlipnik, Črtomir, Grošelj, Uroš, Konc, Janez, Schols, Dominique, Gobec, Stanislav
Publicado 2022

Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti‐SARS‐CoV‐2 Activity

por Schulte, Bianca, König, Maria, Escher, Beate I., Wittenburg, Sophie, Proj, Matic, Wolf, Valentina, Lemke, Carina, Schnakenburg, Gregor, Sosič, Izidor, Streeck, Hendrik, Müller, Christa E., Gütschow, Michael, Steinebach, Christian
Publicado 2022

Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads

por Kollár, Levente, Gobec, Martina, Proj, Matic, Smrdel, Lara, Knez, Damijan, Imre, Tímea, Gömöry, Ágnes, Petri, László, Ábrányi-Balogh, Péter, Csányi, Dorottya, Ferenczy, György G., Gobec, Stanislav, Sosič, Izidor, Keserű, György M.
Publicado 2021

Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

por Steinebach, Christian, Bricelj, Aleša, Murgai, Arunima, Sosič, Izidor, Bischof, Luca, Ng, Yuen Lam Dora, Heim, Christopher, Maiwald, Samuel, Proj, Matic, Voget, Rabea, Feller, Felix, Košmrlj, Janez, Sapozhnikova, Valeriia, Schmidt, Annika, Zuleeg, Maximilian Rudolf, Lemnitzer, Patricia, Mertins, Philipp, Hansen, Finn K., Gütschow, Michael, Krönke, Jan, Hartmann, Marcus D.
Publicado 2023