Sensitive operation of enzyme-based biodevices by advanced signal processing

por Mazurenko, Stanislav, Bidmanova, Sarka, Kotlanova, Marketa, Damborsky, Jiri, Prokop, Zbynek
Publicado 2018

Substrate inhibition by the blockage of product release and its control by tunnel engineering

por Kokkonen, Piia, Beier, Andy, Mazurenko, Stanislav, Damborsky, Jiri, Bednar, David, Prokop, Zbynek
Publicado 2021

CalFitter 2.0: Leveraging the power of singular value decomposition to analyse protein thermostability

por Kunka, Antonin, Lacko, David, Stourac, Jan, Damborsky, Jiri, Prokop, Zbynek, Mazurenko, Stanislav
Publicado 2022

Exploration of Protein Unfolding by Modelling Calorimetry Data from Reheating

por Mazurenko, Stanislav, Kunka, Antonin, Beerens, Koen, Johnson, Christopher M., Damborsky, Jiri, Prokop, Zbynek
Publicado 2017

CalFitter: a web server for analysis of protein thermal denaturation data

por Mazurenko, Stanislav, Stourac, Jan, Kunka, Antonin, Nedeljković, Sava, Bednar, David, Prokop, Zbynek, Damborsky, Jiri
Publicado 2018

The SAP domain of Ku facilitates its efficient loading onto DNA ends

por Fulneček, Jaroslav, Klimentová, Eva, Cairo, Albert, Bukovcakova, Sona Valuchova, Alexiou, Panagiotis, Prokop, Zbynek, Riha, Karel
Publicado 2023

EnzymeMiner: automated mining of soluble enzymes with diverse structures, catalytic properties and stabilities

por Hon, Jiri, Borko, Simeon, Stourac, Jan, Prokop, Zbynek, Zendulka, Jaroslav, Bednar, David, Martinek, Tomas, Damborsky, Jiri
Publicado 2020

Computer-assisted stabilization of fibroblast growth factor FGF-18

por Jan Vilim, Ghazalova, Tereza, Petulova, Eliska, Horackova, Aneta, Stepankova, Veronika, Chaloupkova, Radka, Bednar, David, Damborsky, Jiri, Prokop, Zbynek
Publicado 2023

FireProt: web server for automated design of thermostable proteins

por Musil, Milos, Stourac, Jan, Bendl, Jaroslav, Brezovsky, Jan, Prokop, Zbynek, Zendulka, Jaroslav, Martinek, Tomas, Bednar, David, Damborsky, Jiri
Publicado 2017

Stepwise enhancement of catalytic performance of haloalkane dehalogenase LinB towards β-hexachlorocyclohexane

por Moriuchi, Ryota, Tanaka, Hiroki, Nikawadori, Yuki, Ishitsuka, Mayuko, Ito, Michihiro, Ohtsubo, Yoshiyuki, Tsuda, Masataka, Damborsky, Jiri, Prokop, Zbynek, Nagata, Yuji
Publicado 2014

FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants

por Bednar, David, Beerens, Koen, Sebestova, Eva, Bendl, Jaroslav, Khare, Sagar, Chaloupkova, Radka, Prokop, Zbynek, Brezovsky, Jan, Baker, David, Damborsky, Jiri
Publicado 2015

Fluorescent substrates for haloalkane dehalogenases: Novel probes for mechanistic studies and protein labeling

por Dockalova, Veronika, Sanchez-Carnerero, Esther M., Dunajova, Zuzana, Palao, Eduardo, Slanska, Michaela, Buryska, Tomas, Damborsky, Jiri, Klán, Petr, Prokop, Zbynek
Publicado 2020

The impact of tunnel mutations on enzymatic catalysis depends on the tunnel-substrate complementarity and the rate-limiting step

por Kokkonen, Piia, Slanska, Michaela, Dockalova, Veronika, Pinto, Gaspar P., Sánchez-Carnerero, Esther M., Damborsky, Jiri, Klán, Petr, Prokop, Zbynek, Bednar, David
Publicado 2020

Mechanism-Based Strategy for Optimizing HaloTag Protein Labeling

por Marques, Sérgio M., Slanska, Michaela, Chmelova, Klaudia, Chaloupkova, Radka, Marek, Martin, Clark, Spencer, Damborsky, Jiri, Kool, Eric T., Bednar, David, Prokop, Zbynek
Publicado 2022

Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway

por Dvorak, Pavel, Chrast, Lukas, Nikel, Pablo I., Fedr, Radek, Soucek, Karel, Sedlackova, Miroslava, Chaloupkova, Radka, de Lorenzo, Víctor, Prokop, Zbynek, Damborsky, Jiri
Publicado 2015

Advancing Enzyme’s Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning

por Kunka, Antonin, Marques, Sérgio M., Havlasek, Martin, Vasina, Michal, Velatova, Nikola, Cengelova, Lucia, Kovar, David, Damborsky, Jiri, Marek, Martin, Bednar, David, Prokop, Zbynek
Publicado 2023

Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase

por Papageorgiou, Anna C., Pospisilova, Michaela, Cibulka, Jakub, Ashraf, Raghib, Waudby, Christopher A., Kadeřávek, Pavel, Maroz, Volha, Kubicek, Karel, Prokop, Zbynek, Krejci, Lumir, Tripsianes, Konstantinos
Publicado 2023

Detection of Chloroalkanes by Surface-Enhanced Raman Spectroscopy in Microfluidic Chips

por Pilát, Zdeněk, Kizovský, Martin, Ježek, Jan, Krátký, Stanislav, Sobota, Jaroslav, Šiler, Martin, Samek, Ota, Buryška, Tomáš, Vaňáček, Pavel, Damborský, Jiří, Prokop, Zbyněk, Zemánek, Pavel
Publicado 2018

Computer-aided engineering of staphylokinase toward enhanced affinity and selectivity for plasmin

por Nikitin, Dmitri, Mican, Jan, Toul, Martin, Bednar, David, Peskova, Michaela, Kittova, Patricia, Thalerova, Sandra, Vitecek, Jan, Damborsky, Jiri, Mikulik, Robert, Fleishman, Sarel J., Prokop, Zbynek, Marek, Martin
Publicado 2022

An Ultrasensitive Fluorescence Assay for the Detection of Halides and Enzymatic Dehalogenation

por Aslan‐Üzel, Aşkın S., Beier, Andy, Kovář, David, Cziegler, Clemens, Padhi, Santosh K., Schuiten, Eva D., Dörr, Mark, Böttcher, Dominique, Hollmann, Frank, Rudroff, Florian, Mihovilovic, Marko D., Buryška, Tomáš, Damborský, Jiří, Prokop, Zbyněk, Badenhorst, Christoffel P. S., Bornscheuer, Uwe T.
Publicado 2020