On the Recombination Rate Estimation in the Presence of Population Substructure

por Hecker, Julian, Prokopenko, Dmitry, Lange, Christoph, Fier, Heide Löhlein
Publicado 2015

PolyGEE: a generalized estimating equation approach to the efficient and robust estimation of polygenic effects in large-scale association studies

por Hecker, Julian, Prokopenko, Dmitry, Lange, Christoph, Fier, Heide Loehlein
Publicado 2018

Reply to Neupane et al.: Replication study of AD‐associated rare variants

por Prokopenko, Dmitry, Morgan, Sarah L., Lange, Christoph, Hide, Winston, Bertram, Lars, Tanzi, Rudolph E.
Publicado 2022

Using Network Methodology to Infer Population Substructure

por Prokopenko, Dmitry, Hecker, Julian, Silverman, Edwin, Nöthen, Markus M., Schmid, Matthias, Lange, Christoph, Loehlein Fier, Heide
Publicado 2015

Estimating the effective sample size in association studies of quantitative traits

por Ziyatdinov, Andrey, Kim, Jihye, Prokopenko, Dmitry, Privé, Florian, Laporte, Fabien, Loh, Po-Ru, Kraft, Peter, Aschard, Hugues
Publicado 2021

A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data

por Hahn, Georg, Prokopenko, Dmitry, Lutz, Sharon M., Mullin, Kristina, Tanzi, Rudolph E., Cho, Michael H., Silverman, Edwin K., Lange, Christoph
Publicado 2022

Most Pathways Can Be Related to the Pathogenesis of Alzheimer’s Disease

por Morgan, Sarah L., Naderi, Pourya, Koler, Katjuša, Pita-Juarez, Yered, Prokopenko, Dmitry, Vlachos, Ioannis S., Tanzi, Rudolph E., Bertram, Lars, Hide, Winston A.
Publicado 2022

Gel-based oligonucleotide microarray approach to analyze protein–ssDNA binding specificity

por Zasedateleva, Olga A., Mikheikin, Andrey L., Turygin, Alexander Y., Prokopenko, Dmitry V., Chudinov, Alexander V., Belobritskaya, Elena E., Chechetkin, Vladimir R., Zasedatelev, Alexander S.
Publicado 2008

‘Location, Location, Location’: a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate

por Fier, Heide, Won, Sungho, Prokopenko, Dmitry, AlChawa, Taofik, Ludwig, Kerstin U., Fimmers, Rolf, Silverman, Edwin K., Pagano, Marcello, Mangold, Elisabeth, Lange, Christoph
Publicado 2012

An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo

por Zhang, Xulun, Zhang, Can Martin, Prokopenko, Dmitry, Liang, Yingxia, Zhen, Sherri Y., Weigle, Ian Q., Han, Weinong, Aryal, Manish, Tanzi, Rudolph E., Sisodia, Sangram S.
Publicado 2021

PILRA polymorphism modifies the effect of APOE4 and GM17 on Alzheimer’s disease risk

por Lopatko Lindman, Karin, Jonsson, Caroline, Weidung, Bodil, Olsson, Jan, Pandey, Janardan P., Prokopenko, Dmitry, Tanzi, Rudolph E., Hallmans, Göran, Eriksson, Sture, Elgh, Fredrik, Lövheim, Hugo
Publicado 2022

Whole‐genome sequencing reveals new Alzheimer's disease–associated rare variants in loci related to synaptic function and neuronal development

por Prokopenko, Dmitry, Morgan, Sarah L., Mullin, Kristina, Hofmann, Oliver, Chapman, Brad, Kirchner, Rory, Amberkar, Sandeep, Wohlers, Inken, Lange, Christoph, Hide, Winston, Bertram, Lars, Tanzi, Rudolph E.
Publicado 2021

Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest

por Hahn, Georg, Lee, Sanghun, Prokopenko, Dmitry, Abraham, Jonathan, Novak, Tanya, Hecker, Julian, Cho, Michael, Khurana, Surender, Baden, Lindsey R., Randolph, Adrienne G., Weiss, Scott T., Lange, Christoph
Publicado 2022

Identification of Novel Alzheimer’s Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data

por Prokopenko, Dmitry, Hecker, Julian, Kirchner, Rory, Chapman, Brad A., Hoffman, Oliver, Mullin, Kristina, Hide, Winston, Bertram, Lars, Laird, Nan, DeMeo, Dawn L., Lange, Christoph, Tanzi, Rudolph E.
Publicado 2020

Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer’s disease-associated genes: DTNB and DLG2

por Prokopenko, Dmitry, Lee, Sanghun, Hecker, Julian, Mullin, Kristina, Morgan, Sarah, Katsumata, Yuriko, Weiner, Michael W., Fardo, David W., Laird, Nan, Bertram, Lars, Hide, Winston, Lange, Christoph, Tanzi, Rudolph E.
Publicado 2022

A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables

por Hecker, Julian, Prokopenko, Dmitry, Moll, Matthew, Lee, Sanghun, Kim, Wonji, Qiao, Dandi, Voorhies, Kirsten, Kim, Woori, Vansteelandt, Stijn, Hobbs, Brian D., Cho, Michael H., Silverman, Edwin K., Lutz, Sharon M., DeMeo, Dawn L., Weiss, Scott T., Lange, Christoph
Publicado 2022

Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning

por Neumann, Alexander, Ohlei, Olena, Küçükali, Fahri, Bos, Isabelle J., Timsina, Jigyasha, Vos, Stephanie, Prokopenko, Dmitry, Tijms, Betty M., Andreasson, Ulf, Blennow, Kaj, Vandenberghe, Rik, Scheltens, Philip, Teunissen, Charlotte E., Engelborghs, Sebastiaan, Frisoni, Giovanni B., Blin, Oliver, Richardson, Jill C., Bordet, Régis, Lleó, Alberto, Alcolea, Daniel, Popp, Julius, Marsh, Thomas W., Gorijala, Priyanka, Clark, Christopher, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Dobson, Richard J. B., Legido-Quigley, Cristina, Van Broeckhoven, Christine, Tanzi, Rudolph E., ten Kate, Mara, Lill, Christina M., Barkhof, Frederik, Cruchaga, Carlos, Lovestone, Simon, Streffer, Johannes, Zetterberg, Henrik, Visser, Pieter Jelle, Sleegers, Kristel, Bertram, Lars
Publicado 2023

Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset

por Hong, Shengjun, Prokopenko, Dmitry, Dobricic, Valerija, Kilpert, Fabian, Bos, Isabelle, Vos, Stephanie J. B., Tijms, Betty M., Andreasson, Ulf, Blennow, Kaj, Vandenberghe, Rik, Cleynen, Isabelle, Gabel, Silvy, Schaeverbeke, Jolien, Scheltens, Philip, Teunissen, Charlotte E., Niemantsverdriet, Ellis, Engelborghs, Sebastiaan, Frisoni, Giovanni, Blin, Olivier, Richardson, Jill C., Bordet, Regis, Molinuevo, José Luis, Rami, Lorena, Kettunen, Petronella, Wallin, Anders, Lleó, Alberto, Sala, Isabel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Dobson, Richard J. B., Legido-Quigley, Cristina, Sleegers, Kristel, Van Broeckhoven, Christine, ten Kate, Mara, Barkhof, Frederik, Zetterberg, Henrik, Lovestone, Simon, Streffer, Johannes, Wittig, Michael, Franke, Andre, Tanzi, Rudolph E., Visser, Pieter Jelle, Bertram, Lars
Publicado 2020

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell type and phenotype associations

por Sakornsakolpat, Phuwanat, Prokopenko, Dmitry, Lamontagne, Maxime, Reeve, Nicola F., Guyatt, Anna L., Jackson, Victoria E., Shrine, Nick, Qiao, Dandi, Bartz, Traci M., Kim, Deog Kyeom, Lee, Mi Kyeong, Latourelle, Jeanne C., Li, Xingnan, Morrow, Jarrett D., Obeidat, Ma’en, Wyss, Annah B., Bakke, Per, Barr, R Graham, Beaty, Terri H., Belinsky, Steven A., Brusselle, Guy G., Crapo, James D., de Jong, Kim, DeMeo, Dawn L., Fingerlin, Tasha E., Gharib, Sina A., Gulsvik, Amund, Hall, Ian P., Hokanson, John E., Kim, Woo Jin, Lomas, David A., London, Stephanie J., Meyers, Deborah A., O’Connor, George T., Rennard, Stephen I., Schwartz, David A., Sliwinski, Pawel, Sparrow, David, Strachan, David P., Tal-Singer, Ruth, Tesfaigzi, Yohannes, Vestbo, Jørgen, Vonk, Judith M., Yim, Jae-Joon, Zhou, Xiaobo, Bossé, Yohan, Manichaikul, Ani, Lahousse, Lies, Silverman, Edwin K., Boezen, H. Marike, Wain, Louise V., Tobin, Martin D., Hobbs, Brian D., Cho, Michael H.
Publicado 2019

Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants

por Zhao, Xutong, Qiao, Dandi, Yang, Chaojie, Kasela, Silva, Kim, Wonji, Ma, Yanlin, Shrine, Nick, Batini, Chiara, Sofer, Tamar, Taliun, Sarah A. Gagliano, Sakornsakolpat, Phuwanat, Balte, Pallavi P., Prokopenko, Dmitry, Yu, Bing, Lange, Leslie A., Dupuis, Josée, Cade, Brian E., Lee, Jiwon, Gharib, Sina A., Daya, Michelle, Laurie, Cecelia A., Ruczinski, Ingo, Cupples, L. Adrienne, Loehr, Laura R., Bartz, Traci M., Morrison, Alanna C., Psaty, Bruce M., Vasan, Ramachandran S., Wilson, James G., Taylor, Kent D., Durda, Peter, Johnson, W. Craig, Cornell, Elaine, Guo, Xiuqing, Liu, Yongmei, Tracy, Russell P., Ardlie, Kristin G., Aguet, François, VanDenBerg, David J., Papanicolaou, George J., Rotter, Jerome I., Barnes, Kathleen C., Jain, Deepti, Nickerson, Deborah A., Muzny, Donna M., Metcalf, Ginger A., Doddapaneni, Harshavardhan, Dugan-Perez, Shannon, Gupta, Namrata, Gabriel, Stacey, Rich, Stephen S., O’Connor, George T., Redline, Susan, Reed, Robert M., Laurie, Cathy C., Daviglus, Martha L., Preudhomme, Liana K., Burkart, Kristin M., Kaplan, Robert C., Wain, Louise V., Tobin, Martin D., London, Stephanie J., Lappalainen, Tuuli, Oelsner, Elizabeth C., Abecasis, Goncalo R., Silverman, Edwin K., Barr, R. Graham, Cho, Michael H., Manichaikul, Ani
Publicado 2020