Concentrations of besifloxacin, gatifloxacin, and moxifloxacin in human conjunctiva after topical ocular administration

por Torkildsen, Gail, Proksch, Joel W, Shapiro, Aron, Lynch, Stephanie K, Comstock, Timothy L
Publicado 2010

Omaveloxolone and TX63682 are hepatoprotective in the STAM mouse model of nonalcoholic steatohepatitis

por Reisman, Scott A., Ferguson, Deborah A., Lee, Chun‐Yue I., Proksch, Joel W.
Publicado 2020

Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates

por Reisman, Scott A, Gahir, Sarabjit S, Lee, Chun-Yue I, Proksch, Joel W, Sakamoto, Mitsumasa, Ward, Keith W
Publicado 2019

Topical application of RTA 408 lotion activates Nrf2 in human skin and is well-tolerated by healthy human volunteers

por Reisman, Scott A., Goldsberry, Angela R., Lee, Chun-Yue I., O’Grady, Megan L., Proksch, Joel W., Ward, Keith W., Meyer, Colin J.
Publicado 2015

Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function

por Nagasu, Hajime, Sogawa, Yuji, Kidokoro, Kengo, Itano, Seiji, Yamamoto, Toshiya, Satoh, Minoru, Sasaki, Tamaki, Suzuki, Takafumi, Yamamoto, Masayuki, Wigley, W. Christian, Proksch, Joel W., Meyer, Colin J., Kashihara, Naoki
Publicado 2019

Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors

por Creelan, Ben C, Gabrilovich, Dmitry I, Gray, Jhanelle E, Williams, Charles C, Tanvetyanon, Tawee, Haura, Eric B, Weber, Jeffrey S, Gibney, Geoffrey T, Markowitz, Joseph, Proksch, Joel W, Reisman, Scott A, McKee, Mark D, Chin, Melanie P, Meyer, Colin J, Antonia, Scott J
Publicado 2017