SUN-653 Bypassing Skeletal Muscle Lipid Handling Deficiencies as a Therapy for Metabolic Disease

por Fan, Liyan, Sweet, David R, Prosdocimo, Domenick A, Keerthy, Komal S, Jain, Mukesh K
Publicado 2020

KLF15 and PPARα Cooperate to Regulate Cardiomyocyte Lipid Gene Expression and Oxidation

por Prosdocimo, Domenick A., John, Jenine E., Zhang, Lilei, Efraim, Elizabeth S., Zhang, Rongli, Liao, Xudong, Jain, Mukesh K.
Publicado 2015

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects

por Zhao, Yuanyuan, Sun, Xiaoyan, Hu, Di, Prosdocimo, Domenick A., Hoppel, Charles, Jain, Mukesh K., Ramachandran, Rajesh, Qi, Xin
Publicado 2019

Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse

por Matsakas, Antonios, Prosdocimo, Domenick A., Mitchell, Robert, Collins-Hooper, Henry, Giallourou, Natasa, Swann, Jonathan R., Potter, Paul, Epting, Thomas, Jain, Mukesh K., Patel, Ketan
Publicado 2015

Transcription factors KLF15 and PPARδ cooperatively orchestrate genome-wide regulation of lipid metabolism in skeletal muscle

por Fan, Liyan, Sweet, David R., Fan, Erica K., Prosdocimo, Domenick A., Madera, Annmarie, Jiang, Zhen, Padmanabhan, Roshan, Haldar, Saptarsi M., Vinayachandran, Vinesh, Jain, Mukesh K.
Publicado 2022

Kruppel-like factor 15 is required for the cardiac adaptive response to fasting

por Sugi, Keiki, Hsieh, Paishiun N., Ilkayeva, Olga, Shelkay, Shamanthika, Moroney, Bridget, Baadh, Palvir, Haynes, Browning, Pophal, Megan, Fan, Liyan, Newgard, Christopher B., Prosdocimo, Domenick A., Jain, Mukesh K.
Publicado 2018

Corrigendum: Circadian control of bile acid synthesis by a KLF15-Fgf15 axis

por Han, Shuxin, Zhang, Rongli, Jain, Rajan, Shi, Hong, Zhang, Lilei, Zhou, Guangjin, Sangwung, Panjamaporn, Tugal, Derin, Atkins, G. Brandon, Prosdocimo, Domenick A., Lu, Yuan, Han, Xiaonan, Tso, Patrick, Liao, Xudong, Epstein, Jonathan A., Jain, Mukesh K.
Publicado 2015

Circadian control of bile acid synthesis by a KLF15-Fgf15 axis

por Han, Sean (Shuxin), Zhang, Rongli, Jain, Rajan, Shi, Hong, Zhang, Lilei, Zhou, Guangjin, Sangwung, Panjamaporn, Tugal, Derin, Atkins, G. Brandon, Prosdocimo, Domenick A., Lu, Yuan, Han, Xiaonan, Tso, Patrick, Liao, Xudong, Epstein, Jonathan A., Jain, Mukesh K.
Publicado 2015

A conserved KLF-autophagy pathway modulates nematode lifespan and mammalian age-associated vascular dysfunction

por Hsieh, Paishiun N., Zhou, Guangjin, Yuan, Yiyuan, Zhang, Rongli, Prosdocimo, Domenick A., Sangwung, Panjamaporn, Borton, Anna H., Boriushkin, Evgenii, Hamik, Anne, Fujioka, Hisashi, Fealy, Ciaran E., Kirwan, John P., Peters, Maureen, Lu, Yuan, Liao, Xudong, Ramírez-Bergeron, Diana, Feng, Zhaoyang, Jain, Mukesh K.
Publicado 2017

KLF15 Is a Molecular Link between Endoplasmic Reticulum Stress and Insulin Resistance

por Jung, Dae Young, Chalasani, UmaDevi, Pan, Ning, Friedline, Randall H., Prosdocimo, Domenick A., Nam, Minwoo, Azuma, Yoshihiro, Maganti, Rajanikanth, Yu, Kristine, Velagapudi, Ashish, O’Sullivan-Murphy, Bryan, Sartoretto, Juliano L., Jain, Mukesh K., Cooper, Marcus P., Urano, Fumihiko, Kim, Jason K., Gray, Susan
Publicado 2013

Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice

por Walter, Lisa M., Deguise, Marc-Olivier, Meijboom, Katharina E., Betts, Corinne A., Ahlskog, Nina, van Westering, Tirsa L.E., Hazell, Gareth, McFall, Emily, Kordala, Anna, Hammond, Suzan M., Abendroth, Frank, Murray, Lyndsay M., Shorrock, Hannah K., Prosdocimo, Domenick A., Haldar, Saptarsi M., Jain, Mukesh K., Gillingwater, Thomas H., Claus, Peter, Kothary, Rashmi, Wood, Matthew J.A., Bowerman, Melissa
Publicado 2018