Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis

por Prosser, Gareth A., de Carvalho, Luiz P. S.
Publicado 2013

Reinterpreting the Mechanism of Inhibition of Mycobacterium tuberculosisd-Alanine:d-Alanine Ligase by d-Cycloserine

por Prosser, Gareth A., de Carvalho, Luiz Pedro S.
Publicado 2013

Correction to Reinterpreting the Mechanism of Inhibition of Mycobacterium tuberculosisd-Alanine:d-Alanine Ligase by d-Cycloserine

por Prosser, Gareth A., de Carvalho, Luiz Pedro S.
Publicado 2013

Metabolomic strategies for the identification of new enzyme functions and metabolic pathways

por Prosser, Gareth A, Larrouy-Maumus, Gerald, de Carvalho, Luiz Pedro S
Publicado 2014

Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis

por de Chiara, Cesira, Prosser, Gareth A., Ogrodowicz, Roksana, de Carvalho, Luiz P. S.
Publicado 2023

Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis

por Prosser, Gareth A., Rodenburg, Anne, Khoury, Hania, de Chiara, Cesira, Howell, Steve, Snijders, Ambrosius P., de Carvalho, Luiz Pedro S.
Publicado 2016

Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes

por Evangelopoulos, Dimitrios, Prosser, Gareth A., Rodgers, Angela, Dagg, Belinda M., Khatri, Bhagwati, Ho, Mei Mei, Gutierrez, Maximiliano G., Cortes, Teresa, de Carvalho, Luiz Pedro S.
Publicado 2019

d-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition

por de Chiara, Cesira, Homšak, Miha, Prosser, Gareth A., Douglas, Holly L., Garza-Garcia, Acely, Kelly, Geoff, Purkiss, Andrew G., Tate, Edward W., de Carvalho, Luiz Pedro S.
Publicado 2020

Development and Optimization of Chromosomally-Integrated Fluorescent Mycobacterium tuberculosis Reporter Constructs

por Kolbe, Katharina, Bell, Alice C., Prosser, Gareth A., Assmann, Maike, Yang, Hee-Jeong, Forbes, He Eun, Gallucci, Sophia, Mayer-Barber, Katrin D., Boshoff, Helena I., Barry III, Clifton E.
Publicado 2020

Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3

por Abbattista, Maria R., Ashoorzadeh, Amir, Guise, Christopher P., Mowday, Alexandra M., Mittra, Rituparna, Silva, Shevan, Hicks, Kevin O., Bull, Matthew R., Jackson-Patel, Victoria, Lin, Xiaojing, Prosser, Gareth A., Lambie, Neil K., Dachs, Gabi U., Ackerley, David F., Smaill, Jeff B., Patterson, Adam V.
Publicado 2021

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribu...

por Murugesan, Dinakaran, Ray, Peter C., Bayliss, Tracy, Prosser, Gareth A., Harrison, Justin R., Green, Kirsteen, Soares de Melo, Candice, Feng, Tzu-Shean, Street, Leslie J., Chibale, Kelly, Warner, Digby F., Mizrahi, Valerie, Epemolu, Ola, Scullion, Paul, Ellis, Lucy, Riley, Jennifer, Shishikura, Yoko, Ferguson, Liam, Osuna-Cabello, Maria, Read, Kevin D., Green, Simon R., Lamprecht, Dirk A., Finin, Peter M., Steyn, Adrie J. C., Ioerger, Thomas R., Sacchettini, Jim, Rhee, Kyu Y., Arora, Kriti, Barry, Clifton E., Wyatt, Paul G., Boshoff, Helena I. M.
Publicado 2018