Abiraterone acetate in combination with prednisone in the treatment of metastatic hormone-sensitive prostate cancer: clinical evidence and experience

por Purshouse, Karin, Protheroe, Andrew S.
Publicado 2019

Review of Adjuvant Therapies in Renal Cell Carcinoma: Evidence to Date

por Tacconi, Eliana M C, Tuthill, Mark, Protheroe, Andrew
Publicado 2020

Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma

por Purshouse, Karin, Chamberlain, Sarah, Soares, Maria, Tuthill, Mark, Protheroe, Andrew, Mole, David R.
Publicado 2019

RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition

por Earwaker, Philip, Anderson, Caroline, Willenbrock, Frances, Harris, Adrian L., Protheroe, Andrew S., Macaulay, Valentine M.
Publicado 2018

Genomic sequencing in oncology: Considerations for integration in routine cancer care

por Rahman, Belinda, Lamb, Alastair, Protheroe, Andrew, Shah, Ketan, Solomons, Joyce, Williams, Jonathan, Ormondroyd, Elizabeth
Publicado 2022

IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination

por Chitnis, Meenali M., Lodhia, Kunal A., Aleksic, Tamara, Gao, Shan, Protheroe, Andrew S., Macaulay, Valentine M.
Publicado 2013

The Potential of Artificial Intelligence to Detect Lymphovascular Invasion in Testicular Cancer

por Ghosh, Abhisek, Sirinukunwattana, Korsuk, Khalid Alham, Nasullah, Browning, Lisa, Colling, Richard, Protheroe, Andrew, Protheroe, Emily, Jones, Stephanie, Aberdeen, Alan, Rittscher, Jens, Verrill, Clare
Publicado 2021

The Use of Digital Pathology and Artificial Intelligence in Histopathological Diagnostic Assessment of Prostate Cancer: A Survey of Prostate Cancer UK Supporters

por Rakovic, Kai, Colling, Richard, Browning, Lisa, Dolton, Monica, Horton, Margaret R., Protheroe, Andrew, Lamb, Alastair D., Bryant, Richard J., Scheffer, Richard, Crofts, James, Stanislaus, Ewart, Verrill, Clare
Publicado 2022

Development of a best-practice clinical guideline for the use of bleomycin in the treatment of germ cell tumours in the UK

por Watson, Robert A., De La Peña, Hugo, Tsakok, Maria T., Joseph, Johnson, Stoneham, Sara, Shamash, Jonathan, Joffe, Johnathan, Mazhar, Danish, Traill, Zoe, Ho, Ling-Pei, Brand, Sue, Protheroe, Andrew S.
Publicado 2018

SUCCINCT: An Open-label, Single-arm, Non-randomised, Phase 2 Trial of Gemcitabine and Cisplatin Chemotherapy in Combination with Sunitinib as First-line Treatment for Patients with...

por Geldart, Thomas, Chester, John, Casbard, Angela, Crabb, Simon, Elliott, Tony, Protheroe, Andrew, Huddart, Robert A., Mead, Graham, Barber, Jim, Jones, Robert J., Smith, Joanna, Cowles, Robert, Evans, Jessica, Griffiths, Gareth
Publicado 2015

Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types

por Rao, Srinivasa R., Protheroe, Andrew, Cerundolo, Lucia, Maldonado-Perez, David, Browning, Lisa, Lamb, Alastair D., Bryant, Richard J., Mills, Ian G., Woodcock, Dan J., Hamdy, Freddie C., Tomlinson, Ian P. M., Verrill, Clare
Publicado 2023

Whole-genome sequencing identifies homozygous BRCA2 deletion guiding treatment in dedifferentiated prostate cancer

por Purshouse, Karin, Schuh, Anna, Fairfax, Benjamin P., Knight, Sam, Antoniou, Pavlos, Dreau, Helene, Popitsch, Niko, Gatter, Kevin, Roberts, Ian, Browning, Lisa, Traill, Zoe, Kerr, David, Verrill, Clare, Tuthill, Mark, Taylor, Jenny C., Protheroe, Andrew
Publicado 2017

PemBla: A Phase 1 study of intravesical pembrolizumab in recurrent non‐muscle‐invasive bladder cancer

por Woodcock, Victoria K., Chen, Ji‐Li, Purshouse, Karin, Butcher, Chrissie, Collins, Linda, Haddon, Caroline, Verrall, Gillian, Elhussein, Leena, Roberts, Corran, Tarlton, Andrea, Rei, Margarida, Napolitani, Giorgio, Salio, Mariolina, Middleton, Mark R., Cerundolo, Vincenzo, Crew, Jeremy, Protheroe, Andrew S.
Publicado 2023

Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?

por Cheung, Vincent Ting Fung, Gupta, Tarun, Olsson-Brown, Anna, Subramanian, Sreedhar, Sasson, Sarah Christina, Heseltine, Jonathan, Fryer, Eve, Collantes, Elena, Sacco, Joseph J., Pirmohamed, Munir, Simmons, Alison, Klenerman, Paul, Tuthill, Mark, Protheroe, Andrew S., Chitnis, Meenali, Fairfax, Benjamin Peter, Payne, Miranda Jane, Middleton, Mark Ross, Brain, Oliver
Publicado 2020

Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial

por James, Nicholas D, Sydes, Matthew R, Mason, Malcolm D, Clarke, Noel W, Anderson, John, Dearnaley, David P, Dwyer, John, Jovic, Gordana, Ritchie, Alastair WS, Russell, J Martin, Sanders, Karen, Thalmann, George N, Bertelli, Gianfilippo, Birtle, Alison J, O'Sullivan, Joe M, Protheroe, Andrew, Sheehan, Denise, Srihari, Narayanan, Parmar, Mahesh KB
Publicado 2012

Safety and immunogenicity of novel 5T4 viral vectored vaccination regimens in early stage prostate cancer: a phase I clinical trial

por Cappuccini, Federica, Bryant, Richard, Pollock, Emily, Carter, Lucy, Verrill, Clare, Hollidge, Julianne, Poulton, Ian, Baker, Megan, Mitton, Celia, Baines, Andrea, Meier, Armin, Schmidt, Guenter, Harrop, Richard, Protheroe, Andrew, MacPherson, Ruth, Kennish, Steven, Morgan, Susan, Vigano, Selena, Romero, Pedro J, Evans, Thomas, Catto, James, Hamdy, Freddie, Hill, Adrian V S, Redchenko, Irina
Publicado 2020

Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing

por Schuh, Anna, Dreau, Helene, Knight, Samantha J.L., Ridout, Kate, Mizani, Tuba, Vavoulis, Dimitris, Colling, Richard, Antoniou, Pavlos, Kvikstad, Erika M., Pentony, Melissa M., Hamblin, Angela, Protheroe, Andrew, Parton, Marina, Shah, Ketan A., Orosz, Zsolt, Athanasou, Nick, Hassan, Bass, Flanagan, Adrienne M., Ahmed, Ahmed, Winter, Stuart, Harris, Adrian, Tomlinson, Ian, Popitsch, Niko, Church, David, Taylor, Jenny C.
Publicado 2018

The WIRE study a phase II, multi-arm, multi-centre, non-randomised window-of-opportunity clinical trial platform using a Bayesian adaptive design for proof-of-mechanism of novel tr...

por Ursprung, Stephan, Mossop, Helen, Gallagher, Ferdia A., Sala, Evis, Skells, Richard, Sipple, Jamal A. N., Mitchell, Thomas J., Chhabra, Anita, Fife, Kate, Matakidou, Athena, Young, Gemma, Walker, Amanda, Thomas, Martin G., Ortuzar, Mireia Crispin, Sullivan, Mark, Protheroe, Andrew, Oades, Grenville, Venugopal, Balaji, Warren, Anne Y., Stone, John, Eisen, Tim, Wason, James, Welsh, Sarah J., Stewart, Grant D.
Publicado 2021

Digital Pathology Transformation in a Supraregional Germ Cell Tumour Network

por Colling, Richard, Protheroe, Andrew, Sullivan, Mark, Macpherson, Ruth, Tuthill, Mark, Redgwell, Jacqueline, Traill, Zoe, Molyneux, Angus, Johnson, Elizabeth, Abdullah, Niveen, Taibi, Andrea, Mercer, Nikki, Haynes, Harry R., Sackville, Anthony, Craft, Judith, Reis, Joao, Rees, Gabrielle, Soares, Maria, Roberts, Ian S. D., Siiankoski, Darrin, Hemsworth, Helen, Roskell, Derek, Roberts-Gant, Sharon, White, Kieron, Rittscher, Jens, Davies, Jim, Browning, Lisa, Verrill, Clare
Publicado 2021

Interferon-Gamma–Producing CD8(+) Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor–Colitis

por Sasson, Sarah C., Slevin, Stephanie M., Cheung, Vincent T.F., Nassiri, Isar, Olsson-Brown, Anna, Fryer, Eve, Ferreira, Ricardo C., Trzupek, Dominik, Gupta, Tarun, Al-Hillawi, Lulia, Issaias, Mari-lenna, Easton, Alistair, Campo, Leticia, FitzPatrick, Michael E.B., Adams, Joss, Chitnis, Meenali, Protheroe, Andrew, Tuthill, Mark, Coupe, Nicholas, Simmons, Alison, Payne, Miranda, Middleton, Mark R., Travis, Simon P.L., Fairfax, Benjamin P., Klenerman, Paul, Brain, Oliver
Publicado 2021