Mechanisms of eukaryotic transcription

por Pufall, Miles A, Kaplan, Craig D
Publicado 2013

PI3Kδ inhibition potentiates glucocorticoids in B-lymphoblastic leukemia by decreasing receptor phosphorylation and enhancing gene regulation

por Zimmerman, Jessica A.O., Fang, Mimi, Pufall, Miles A.
Publicado 2023

Checkpoint activation drives global gene expression changes in Drosophila nuclear lamina mutants

por Kitzman, Samuel Cole, Duan, Tingting, Pufall, Miles A, Geyer, Pamela K
Publicado 2021

Increasing G9a automethylation sensitizes B acute lymphoblastic leukemia cells to glucocorticoid-induced death

por Poulard, Coralie, Baulu, Estelle, Lee, Brian H., Pufall, Miles A., Stallcup, Michael R.
Publicado 2018

Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes

por Zhang, Liyang, Rube, H Tomas, Vakulskas, Christopher A, Behlke, Mark A, Bussemaker, Harmen J, Pufall, Miles A
Publicado 2020

The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

por Watson, Lisa C., Kuchenbecker, Kristopher M., Schiller, Benjamin J., Gross, John D., Pufall, Miles A., Yamamoto, Keith R.
Publicado 2013

Transcriptional Regulation of Human Dual Specificity Protein Phosphatase 1 (DUSP1) Gene by Glucocorticoids

por Shipp, Lauren E., Lee, Joyce V., Yu, Chi-Yi, Pufall, Miles, Zhang, Pili, Scott, Donald K., Wang, Jen-Chywan
Publicado 2010

Mechanistic Investigation of the Androgen Receptor DNA-Binding Domain Inhibitor Pyrvinium

por Pal, Sumanta K., Tew, Ben Yi, Lim, Minyoung, Stankavich, Brittany, He, Miaoling, Pufall, Miles, Hu, Weidong, Chen, Yuan, Jones, Jeremy O.
Publicado 2019

De novo distillation of thermodynamic affinity from deep learning regulatory sequence models of in vivo protein-DNA binding

por Alexandari, Amr M., Horton, Connor A., Shrikumar, Avanti, Shah, Nilay, Li, Eileen, Weilert, Melanie, Pufall, Miles A., Zeitlinger, Julia, Fordyce, Polly M., Kundaje, Anshul
Publicado 2023

Transcriptional coactivation by EHMT2 restricts glucocorticoid-induced insulin resistance in a study with male mice

por Lee, Rebecca A., Chang, Maggie, Yiv, Nicholas, Tsay, Ariel, Tian, Sharon, Li, Danielle, Poulard, Coralie, Stallcup, Michael R., Pufall, Miles A., Wang, Jen-Chywan
Publicado 2023

Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression

por Sasse, Sarah K., Gruca, Margaret, Allen, Mary A., Kadiyala, Vineela, Song, Tengyao, Gally, Fabienne, Gupta, Arnav, Pufall, Miles A., Dowell, Robin D., Gerber, Anthony N.
Publicado 2019

IL6Myc mouse is an immunocompetent model for the development of aggressive multiple myeloma

por Pisano, Michael D., Sun, Fumou, Cheng, Yan, Parashar, Deepak, Zhou, Vivian, Jing, Xuefang, Sompallae, Ramakrishna, Abrudan, Jenica, Zimmermann, Michael T., Mathison, Angela, Janz, Siegfried, Pufall, Miles A.
Publicado 2023

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

por Serafimova, Iana M., Pufall, Miles A., Krishnan, Shyam, Duda, Katarzyna, Cohen, Michael S., Maglathlin, Rebecca L., McFarland, Jesse M., Miller, Rand M., Frödin, Morten, Taunton, Jack
Publicado 2012

SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site

por Zhang, Liyang, Martini, Gabriella D., Rube, H. Tomas, Kribelbauer, Judith F., Rastogi, Chaitanya, FitzPatrick, Vincent D., Houtman, Jon C., Bussemaker, Harmen J., Pufall, Miles A.
Publicado 2018

UV irradiation remodels the specificity landscape of transcription factors

por Mielko, Zachery, Zhang, Yuning, Sahay, Harshit, Liu, Yiling, Schaich, Matthew A., Schnable, Brittani, Morrison, Abigail M., Burdinski, Debbie, Adar, Sheera, Pufall, Miles, Van Houten, Bennett, Gordân, Raluca, Afek, Ariel
Publicado 2023

Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages

por Rollins, David A., Kharlyngdoh, Joubert B., Coppo, Maddalena, Tharmalingam, Bowranigan, Mimouna, Sanda, Guo, Ziyi, Sacta, Maria A., Pufall, Miles A., Fisher, Robert P., Hu, Xiaoyu, Chinenov, Yurii, Rogatsky, Inez
Publicado 2017

A De Novo Sequence Variant in Barrier-to-Autointegration Factor Is Associated with Dominant Motor Neuronopathy

por Marcelot, Agathe, Rodriguez-Tirado, Felipe, Cuniasse, Philippe, Joiner, Mei-ling, Miron, Simona, Soshnev, Alexey A., Fang, Mimi, Pufall, Miles A., Mathews, Katherine D., Moore, Steven A., Zinn-Justin, Sophie, Geyer, Pamela K.
Publicado 2023

Characterization of HCI-EC-23 a novel estrogen- and progesterone-responsive endometrial cancer cell line

por Rush, Craig M., Blanchard, Zannel, Polaski, Jacob T., Osborne, Kyle S., Osby, Krystle, Vahrenkamp, Jeffery M., Yang, Chieh-Hsiang, Lum, David H., Hagan, Christy R., Leslie, Kimberly K., Pufall, Miles A., Thiel, Kristina W., Gertz, Jason
Publicado 2022

DNA mismatches reveal conformational penalties in protein-DNA recognition

por Afek, Ariel, Shi, Honglue, Rangadurai, Atul, Sahay, Harshit, Senitzki, Alon, Xhani, Suela, Fang, Mimi, Salinas, Raul, Mielko, Zachery, Pufall, Miles A., Poon, Gregory M.K., Haran, Tali E., Schumacher, Maria A., Al-Hashimi, Hashim M., Gordan, Raluca
Publicado 2020

Metabolic gatekeeper function of B-lymphoid transcription factors

por Chan, Lai N., Chen, Zhengshan, Braas, Daniel, Lee, Jae-Woong, Xiao, Gang, Geng, Huimin, Cosgun, Kadriye Nehir, Hurtz, Christian, Shojaee, Seyedmehdi, Cazzaniga, Valeria, Schjerven, Hilde, Ernst, Thomas, Hochhaus, Andreas, Kornblau, Steven M., Konopleva, Marina, Pufall, Miles A., Cazzaniga, Giovanni, Liu, Grace J., Milne, Thomas A., Koeffler, H. Philip, Ross, Theodora S., Sanchez-Garcia, Isidro, Borkhardt, Arndt, Yamamoto, Keith R., Dickins, Ross A., Graeber, Thomas G., Müschen, Markus
Publicado 2017