Exotoxin-Targeted Drug Modalities as Antibiotic Alternatives

por Sakari, Moona, Laisi, Arttu, Pulliainen, Arto T.
Publicado 2022

Human Peptides α-Defensin-1 and -5 Inhibit Pertussis Toxin

por Kling, Carolin, Pulliainen, Arto T., Barth, Holger, Ernst, Katharina
Publicado 2021

Bats as Reservoir Hosts of Human Bacterial Pathogen, Bartonella mayotimonensis

por Veikkolainen, Ville, Vesterinen, Eero J., Lilley, Thomas M., Pulliainen, Arto T.
Publicado 2014

iGIST—A Kinetic Bioassay for Pertussis Toxin Based on Its Effect on Inhibitory GPCR Signaling

por Paramonov, Valeriy M., Sahlgren, Cecilia, Rivero-Müller, Adolfo, Pulliainen, Arto T.
Publicado 2020

Crystal structures of pertussis toxin with NAD(+) and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity

por Sakari, Moona, Tran, Mai T., Rossjohn, Jamie, Pulliainen, Arto T., Beddoe, Travis, Littler, Dene R.
Publicado 2022

Genome-wide screen of gamma-secretase–mediated intramembrane cleavage of receptor tyrosine kinases

por Merilahti, Johannes A. M., Ojala, Veera K., Knittle, Anna M., Pulliainen, Arto T., Elenius, Klaus
Publicado 2017

Domperidone Inhibits Clostridium botulinum C2 Toxin and Bordetella pertussis Toxin

por Jia, Jinfang, Braune-Yan, Maria, Lietz, Stefanie, Wahba, Mary, Pulliainen, Arto T., Barth, Holger, Ernst, Katharina
Publicado 2023

Different responses of colorectal cancer cells to alternative sequences of cetuximab and oxaliplatin

por Narvi, Elli, Vaparanta, Katri, Karrila, Anna, Chakroborty, Deepankar, Knuutila, Sakari, Pulliainen, Arto, Sundvall, Maria, Elenius, Klaus
Publicado 2018

Microbiome Analysis Reveals the Presence of Bartonella spp. and Acinetobacter spp. in Deer Keds (Lipoptena cervi)

por Regier, Yvonne, Komma, Kassandra, Weigel, Markus, Pulliainen, Arto T., Göttig, Stephan, Hain, Torsten, Kempf, Volkhard A. J.
Publicado 2018

Single-Peptide TR-FRET Detection Platform for Cysteine-Specific Post-Translational Modifications

por Eskonen, Ville, Tong-Ochoa, Natalia, Mattsson, Leena, Miettinen, Moona, Lastusaari, Mika, Pulliainen, Arto T., Kopra, Kari, Härmä, Harri
Publicado 2020

Systemic Analysis of Gene Expression Profiles Identifies ErbB3 as a Potential Drug Target in Pediatric Alveolar Rhabdomyosarcoma

por Nordberg, Janne, Mpindi, John Patrick, Iljin, Kristiina, Pulliainen, Arto Tapio, Kallajoki, Markku, Kallioniemi, Olli, Elenius, Klaus, Elenius, Varpu
Publicado 2012

Combination of microbiome analysis and serodiagnostics to assess the risk of pathogen transmission by ticks to humans and animals in central Germany

por Regier, Yvonne, Komma, Kassandra, Weigel, Markus, Kraiczy, Peter, Laisi, Arttu, Pulliainen, Arto T., Hain, Torsten, Kempf, Volkhard A. J.
Publicado 2019

Homogeneous Dual-Parametric-Coupled Assay for Simultaneous Nucleotide Exchange and KRAS/RAF-RBD Interaction Monitoring

por Kopra, Kari, Vuorinen, Emmiliisa, Abreu-Blanco, Maria, Wang, Qi, Eskonen, Ville, Gillette, William, Pulliainen, Arto T., Holderfield, Matthew, Härmä, Harri
Publicado 2020

Inhibition of Pertussis Toxin by Human α-Defensins-1 and -5: Differential Mechanisms of Action

por Kling, Carolin, Sommer, Anja, Almeida-Hernandez, Yasser, Rodríguez, Armando, Perez-Erviti, Julio A., Bhadane, Rajendra, Ständker, Ludger, Wiese, Sebastian, Barth, Holger, Pupo-Meriño, Mario, Pulliainen, Arto T., Sánchez-García, Elsa, Ernst, Katharina
Publicado 2023

Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo

por Ernst, Katharina, Mittler, Ann-Katrin, Winkelmann, Veronika, Kling, Carolin, Eberhardt, Nina, Anastasia, Anna, Sonnabend, Michael, Lochbaum, Robin, Wirsching, Jan, Sakari, Moona, Pulliainen, Arto T., Skerry, Ciaran, Carbonetti, Nicholas H., Frick, Manfred, Barth, Holger
Publicado 2021

Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems

por Gillespie, Joseph J., Phan, Isabelle Q. H., Scheib, Holger, Subramanian, Sandhya, Edwards, Thomas E., Lehman, Stephanie S., Piitulainen, Hanna, Sayeedur Rahman, M., Rennoll-Bankert, Kristen E., Staker, Bart L., Taira, Suvi, Stacy, Robin, Myler, Peter J., Azad, Abdu F., Pulliainen, Arto T.
Publicado 2015