Family-based genetic risk prediction of multifactorial disease

por Ruderfer, Douglas M, Korn, Joshua, Purcell, Shaun M
Publicado 2010

Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results

por Wray, Naomi R., Purcell, Shaun M., Visscher, Peter M.
Publicado 2011

Sources of Variation in the Spectral Slope of the Sleep EEG

por Kozhemiako, Nataliia, Mylonas, Dimitris, Pan, Jen Q., Prerau, Michael J., Redline, Susan, Purcell, Shaun M.
Publicado 2022

Second-generation PLINK: rising to the challenge of larger and richer datasets

por Chang, Christopher C, Chow, Carson C, Tellier, Laurent CAM, Vattikuti, Shashaank, Purcell, Shaun M, Lee, James J
Publicado 2015

Protocol for investigating genetic determinants of posttraumatic stress disorder in women from the Nurses' Health Study II

por Koenen, Karestan C, DeVivo, Immaculata, Rich-Edwards, Janet, Smoller, Jordan W, Wright, Rosalind J, Purcell, Shaun M
Publicado 2009

AI-Driven sleep staging from actigraphy and heart rate

por Song, Tzu-An, Chowdhury, Samadrita Roy, Malekzadeh, Masoud, Harrison, Stephanie, Hoge, Terri Blackwell, Redline, Susan, Stone, Katie L., Saxena, Richa, Purcell, Shaun M., Dutta, Joyita
Publicado 2023

Testing for an Unusual Distribution of Rare Variants

por Neale, Benjamin M., Rivas, Manuel A., Voight, Benjamin F., Altshuler, David, Devlin, Bernie, Orho-Melander, Marju, Kathiresan, Sekar, Purcell, Shaun M., Roeder, Kathryn, Daly, Mark J.
Publicado 2011

Patterns of genic intolerance of rare copy number variation in 59,898 human exomes

por Ruderfer, Douglas M., Hamamsy, Tymor, Lek, Monkol, Karczewski, Konrad J., Kavanagh, David, Samocha, Kaitlin E., Daly, Mark J., MacArthur, Daniel G., Fromer, Menachem, Purcell, Shaun M.
Publicado 2016

mTADA is a framework for identifying risk genes from de novo mutations in multiple traits

por Nguyen, Tan-Hoang, Dobbyn, Amanda, Brown, Ruth C., Riley, Brien P., Buxbaum, Joseph D., Pinto, Dalila, Purcell, Shaun M., Sullivan, Patrick F., He, Xin, Stahl, Eli A.
Publicado 2020

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

por Raychaudhuri, Soumya, Plenge, Robert M., Rossin, Elizabeth J., Ng, Aylwin C. Y., Purcell, Shaun M., Sklar, Pamela, Scolnick, Edward M., Xavier, Ramnik J., Altshuler, David, Daly, Mark J.
Publicado 2009

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

por Genovese, Giulio, Fromer, Menachem, Stahl, Eli A., Ruderfer, Douglas M., Chambert, Kimberly, Landén, Mikael, Moran, Jennifer L., Purcell, Shaun M., Sklar, Pamela, Sullivan, Patrick F., Hultman, Christina M., McCarroll, Steven A.
Publicado 2016

Sleep Architecture, Obstructive Sleep Apnea, and Cognitive Function in Adults

por Pase, Matthew P., Harrison, Stephanie, Misialek, Jeffrey R., Kline, Christopher E., Cavuoto, Marina, Baril, Andree-Ann, Yiallourou, Stephanie, Bisson, Alycia, Himali, Dibya, Leng, Yue, Yang, Qiong, Seshadri, Sudha, Beiser, Alexa, Gottesman, Rebecca F., Redline, Susan, Lopez, Oscar, Lutsey, Pamela L., Yaffe, Kristine, Stone, Katie L., Purcell, Shaun M., Himali, Jayandra J.
Publicado 2023

Macro and micro sleep architecture and cognitive performance in older adults

por Djonlagic, Ina, Mariani, Sara, Fitzpatrick, Annette L., Van Der Klei, Veerle M. G. T. H., Johnson, Dayna, Wood, Alexis C., Seeman, Teresa, Nguyen, Ha T., Prerau, Michael J., Luchsinger, José A., Dzierzewski, Joseph M., Rapp, Stephen R., Tranah, Gregory J., Yaffe, Kristine, Burdick, Katherine E., Stone, Katie L., Redline, Susan, Purcell, Shaun M.
Publicado 2021

The Genetic Structure of the Swedish Population

por Humphreys, Keith, Grankvist, Alexander, Leu, Monica, Hall, Per, Liu, Jianjun, Ripatti, Samuli, Rehnström, Karola, Groop, Leif, Klareskog, Lars, Ding, Bo, Grönberg, Henrik, Xu, Jianfeng, Pedersen, Nancy L., Lichtenstein, Paul, Mattingsdal, Morten, Andreassen, Ole A., O'Dushlaine, Colm, Purcell, Shaun M., Sklar, Pamela, Sullivan, Patrick F., Hultman, Christina M., Palmgren, Juni, Magnusson, Patrik K. E.
Publicado 2011

DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling

por Martin, Pierre-Marie, Stanley, Robert E., Ross, Adam P., Freitas, Andiara E., Moyer, Caitlin E., Brumback, Audrey C., Iafrati, Jillian, Stapornwongkul, Kristina S., Dominguez, Sky, Kivimäe, Saul, Mulligan, Kimberly A., Pirooznia, Mehdi, McCombie, W. Richard, Potash, James B., Zandi, Peter P., Purcell, Shaun M., Sanders, Stephan J., Zuo, Yi, Sohal, Vikaas S., Cheyette, Benjamin N.R.
Publicado 2016

Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

por Nguyen, Hoang T., Bryois, Julien, Kim, April, Dobbyn, Amanda, Huckins, Laura M., Munoz-Manchado, Ana B., Ruderfer, Douglas M., Genovese, Giulio, Fromer, Menachem, Xu, Xinyi, Pinto, Dalila, Linnarsson, Sten, Verhage, Matthijs, Smit, August B., Hjerling-Leffler, Jens, Buxbaum, Joseph D., Hultman, Christina, Sklar, Pamela, Purcell, Shaun M., Lage, Kasper, He, Xin, Sullivan, Patrick F., Stahl, Eli A.
Publicado 2017

Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits

por Ghoshal, Ayan, Uygun, David S., Yang, Lingling, McNally, James M., Lopez-Huerta, Violeta G., Arias-Garcia, Mario A., Baez-Nieto, David, Allen, Andrew, Fitzgerald, Megan, Choi, Soonwook, Zhang, Qiangge, Hope, Jen M., Yan, Karena, Mao, Xiaohong, Nicholson, Thomas B., Imaizumi, Kazuo, Fu, Zhanyan, Feng, Guoping, Brown, Ritchie E., Strecker, Robert E., Purcell, Shaun M., Pan, Jen Q.
Publicado 2020

Non-rapid eye movement sleep and wake neurophysiology in schizophrenia

por Kozhemiako, Nataliia, Wang, Jun, Jiang, Chenguang, Wang, Lei A, Gai, Guanchen, Zou, Kai, Wang, Zhe, Yu, Xiaoman, Zhou, Lin, Li, Shen, Guo, Zhenglin, Law, Robert, Coleman, James, Mylonas, Dimitrios, Shen, Lu, Wang, Guoqiang, Tan, Shuping, Qin, Shengying, Huang, Hailiang, Murphy, Michael, Stickgold, Robert, Manoach, Dara, Zhou, Zhenhe, Zhu, Wei, Hal, Mei-Hua, Purcell, Shaun M, Pan, Jen Q
Publicado 2022

Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study

por Wang, Heming, Kurniansyah, Nuzulul, Cade, Brian E., Goodman, Matthew O., Chen, Han, Gottlieb, Daniel J., Gharib, Sina A., Purcell, Shaun M., Lin, Xihong, Saxena, Richa, Zhu, Xiaofeng, Durda, Peter, Tracy, Russel, Liu, Yongmei, Taylor, Kent D., Johnson, W. Craig, Gabriel, Stacey, Smith, Joshua D., Aguet, François, Ardlie, Kirstin, Blackwell, Tom, Reiner, Alexander P., Rotter, Jerome I., Rich, Stephen S., Redline, Susan, Sofer, Tamar
Publicado 2022

Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

por Fernández, Esperanza, Collins, Mark O., Frank, René A.W., Zhu, Fei, Kopanitsa, Maksym V., Nithianantharajah, Jess, Lemprière, Sarah A., Fricker, David, Elsegood, Kathryn A., McLaughlin, Catherine L., Croning, Mike D.R., Mclean, Colin, Armstrong, J. Douglas, Hill, W. David, Deary, Ian J., Cencelli, Giulia, Bagni, Claudia, Fromer, Menachem, Purcell, Shaun M., Pocklington, Andrew J., Choudhary, Jyoti S., Komiyama, Noboru H., Grant, Seth G.N.
Publicado 2017