Protein evolution on a human signaling network

por Cui, Qinghua, Purisima, Enrico O, Wang, Edwin
Publicado 2009

Principles of microRNA regulation of a human cellular signaling network

por Cui, Qinghua, Yu, Zhenbao, Purisima, Enrico O, Wang, Edwin
Publicado 2006

Coevolved Canonical Loops Conformations of Single-Domain Antibodies: A Tale of Three Pockets Playing Musical Chairs

por Gaudreault, Francis, Corbeil, Christopher R., Purisima, Enrico O., Sulea, Traian
Publicado 2022

Global analysis of microRNA target gene expression reveals that miRNA targets are lower expressed in mature mouse and Drosophila tissues than in the embryos

por Yu, Zhenbao, Jian, Zhaofeng, Shen, Shi-Hsiang, Purisima, Enrico, Wang, Edwin
Publicado 2007

Application of Assisted Design of Antibody and Protein Therapeutics (ADAPT) improves efficacy of a Clostridium difficile toxin A single-domain antibody

por Sulea, Traian, Hussack, Greg, Ryan, Shannon, Tanha, Jamshid, Purisima, Enrico O.
Publicado 2018

Solvated interaction energy: from small-molecule to antibody drug design

por Purisima, Enrico O., Corbeil, Christopher R., Gaudreault, Francis, Wei, Wanlei, Deprez, Christophe, Sulea, Traian
Publicado 2023

An accurate TMT-based approach to quantify and model lysine susceptibility to conjugation via N-hydroxysuccinimide esters in a monoclonal antibody

por Hill, Jennifer J., Tremblay, Tammy-Lynn, Corbeil, Christopher R., Purisima, Enrico O., Sulea, Traian
Publicado 2018

Viral cystatin evolution and three-dimensional structure modelling: A case of directional selection acting on a viral protein involved in a host-parasitoid interaction

por Serbielle, Céline, Chowdhury, Shafinaz, Pichon, Samuel, Dupas, Stéphane, Lesobre, Jérôme, Purisima, Enrico O, Drezen, Jean-Michel, Huguet, Elisabeth
Publicado 2008

Exploring rigid-backbone protein docking in biologics discovery: a test using the DARPin scaffold

por Gaudreault, Francis, Baardsnes, Jason, Martynova, Yuliya, Dachon, Aurore, Hogues, Hervé, Corbeil, Christopher R., Purisima, Enrico O., Arbour, Mélanie, Sulea, Traian
Publicado 2023

A Rational Engineering Strategy for Designing Protein A-Binding Camelid Single-Domain Antibodies

por Henry, Kevin A., Sulea, Traian, van Faassen, Henk, Hussack, Greg, Purisima, Enrico O., MacKenzie, C. Roger, Arbabi-Ghahroudi, Mehdi
Publicado 2016

Identification of high-quality cancer prognostic markers and metastasis network modules

por Li, Jie, Lenferink, Anne E.G., Deng, Yinghai, Collins, Catherine, Cui, Qinghua, Purisima, Enrico O., O'Connor-McCourt, Maureen D., Wang, Edwin
Publicado 2010

Corrigendum: Identification of high-quality cancer prognostic markers and metastasis network modules

por Li, Jie, Lenferink, Anne E.G., Deng, Yinghai, Collins, Catherine, Cui, Qinghua, Purisima, Enrico O., O'Connor-McCourt, Maureen D., Wang, Edwin
Publicado 2012

Redesigning an antibody H3 loop by virtual screening of a small library of human germline-derived sequences

por Corbeil, Christopher R., Manenda, Mahder Seifu, Sulea, Traian, Baardsnes, Jason, Picard, Marie-Ève, Hogues, Hervé, Gaudreault, Francis, Deprez, Christophe, Shi, Rong, Purisima, Enrico O.
Publicado 2021

A map of human cancer signaling

por Cui, Qinghua, Ma, Yun, Jaramillo, Maria, Bari, Hamza, Awan, Arif, Yang, Song, Zhang, Simo, Liu, Lixue, Lu, Meng, O'Connor-McCourt, Maureen, Purisima, Enrico O, Wang, Edwin
Publicado 2007

Assisted Design of Antibody and Protein Therapeutics (ADAPT)

por Vivcharuk, Victor, Baardsnes, Jason, Deprez, Christophe, Sulea, Traian, Jaramillo, Maria, Corbeil, Christopher R., Mullick, Alaka, Magoon, Joanne, Marcil, Anne, Durocher, Yves, O’Connor-McCourt, Maureen D., Purisima, Enrico O.
Publicado 2017

Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment

por Sulea, Traian, Rohani, Nazanin, Baardsnes, Jason, Corbeil, Christopher R., Deprez, Christophe, Cepero-Donates, Yuneivy, Robert, Alma, Schrag, Joseph D., Parat, Marie, Duchesne, Mélanie, Jaramillo, Maria L., Purisima, Enrico O., Zwaagstra, John C.
Publicado 2019

Binding symmetry and surface flexibility mediate antibody self-association

por Schrag, Joseph D., Picard, Marie-Ève, Gaudreault, Francis, Gagnon, Louis-Patrick, Baardsnes, Jason, Manenda, Mahder S., Sheff, Joey, Deprez, Christophe, Baptista, Cassio, Hogues, Hervé, Kelly, John F., Purisima, Enrico O., Shi, Rong, Sulea, Traian
Publicado 2019