Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis

por Purschke, Werner G., Hoehlig, Kai, Buchner, Klaus, Zboralski, Dirk, Schwoebel, Frank, Vater, Axel, Klussmann, Sven
Publicado 2014

A Novel C5a-neutralizing Mirror-image (l-)Aptamer Prevents Organ Failure and Improves Survival in Experimental Sepsis

por Hoehlig, Kai, Maasch, Christian, Shushakova, Nelli, Buchner, Klaus, Huber-Lang, Markus, Purschke, Werner G, Vater, Axel, Klussmann, Sven
Publicado 2013

A Mixed Mirror-image DNA/RNA Aptamer Inhibits Glucagon and Acutely Improves Glucose Tolerance in Models of Type 1 and Type 2 Diabetes

por Vater, Axel, Sell, Simone, Kaczmarek, Przemyslaw, Maasch, Christian, Buchner, Klaus, Pruszynska-Oszmalek, Ewa, Kolodziejski, Pawel, Purschke, Werner G., Nowak, Krzysztof W., Strowski, Mathias Z., Klussmann, Sven
Publicado 2013