An essential role for Grk2 in Hedgehog signalling downstream of Smoothened

por Zhao, Zhonghua, Lee, Raymond Teck Ho, Pusapati, Ganesh V, Iyu, Audrey, Rohatgi, Rajat, Ingham, Philip W
Publicado 2016

Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens

por Patel, Bhaven B., Lebensohn, Andres M., Pusapati, Ganesh V., Carette, Jan E., Salzman, Julia, Rohatgi, Rajat
Publicado 2019

CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog

por Pusapati, Ganesh V., Kong, Jennifer H., Patel, Bhaven B., Krishnan, Arunkumar, Sagner, Andreas, Kinnebrew, Maia, Briscoe, James, Aravind, L., Rohatgi, Rajat
Publicado 2018

Direct ionic stress sensing and mitigation by the transcription factor NFAT5

por Khandwala, Chandni B., Sarkar, Parijat, Schmidt, H. Broder, Ma, Mengxiao, Kinnebrew, Maia, Pusapati, Ganesh V., Patel, Bhaven B., Tillo, Desiree, Lebensohn, Andres M., Rohatgi, Rajat
Publicado 2023

Protein Kinase D2 Is an Essential Regulator of Murine Myoblast Differentiation

por Kleger, Alexander, Loebnitz, Christiane, Pusapati, Ganesh V., Armacki, Milena, Müller, Martin, Tümpel, Stefan, Illing, Anett, Hartmann, Daniel, Brunner, Cornelia, Liebau, Stefan, Rudolph, Karl L., Adler, Guido, Seufferlein, Thomas
Publicado 2011

Allogeneic IgG combined with dendritic cell stimuli induces anti-tumor T cell immunity

por Carmi, Yaron, Spitzer, Matthew H., Linde, Ian L., Burt, Bryan M, Prestwood, Tyler R., Perlman, Nikola, Davidson, Matthew G., Kenkel, Justin A., Segal, Ehud, Pusapati, Ganesh V., Bhattacharya, Nupur, Engleman, Edgar G.
Publicado 2015

R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling

por Dubey, Ramin, van Kerkhof, Peter, Jordens, Ingrid, Malinauskas, Tomas, Pusapati, Ganesh V, McKenna, Joseph K, Li, Dan, Carette, Jan E, Ho, Mitchell, Siebold, Christian, Maurice, Madelon, Lebensohn, Andres M, Rohatgi, Rajat
Publicado 2020

Cholesterol accessibility at the ciliary membrane controls hedgehog signaling

por Kinnebrew, Maia, Iverson, Ellen J, Patel, Bhaven B, Pusapati, Ganesh V, Kong, Jennifer H, Johnson, Kristen A, Luchetti, Giovanni, Eckert, Kaitlyn M, McDonald, Jeffrey G, Covey, Douglas F, Siebold, Christian, Radhakrishnan, Arun, Rohatgi, Rajat
Publicado 2019

Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength

por Kong, Jennifer H., Young, Cullen B., Pusapati, Ganesh V., Espinoza, F. Hernán, Patel, Chandni B., Beckert, Francis, Ho, Sebastian, Patel, Bhaven B., Gabriel, George C., Aravind, L., Bazan, J. Fernando, Gunn, Teresa M., Lo, Cecilia W., Rohatgi, Rajat
Publicado 2021

Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling

por Hong, Shi-Rong, Wang, Cuei-Ling, Huang, Yao-Shen, Chang, Yu-Chen, Chang, Ya-Chu, Pusapati, Ganesh V., Lin, Chun-Yu, Hsu, Ning, Cheng, Hsiao-Chi, Chiang, Yueh-Chen, Huang, Wei-En, Shaner, Nathan C., Rohatgi, Rajat, Inoue, Takanari, Lin, Yu-Chun
Publicado 2018

Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling

por Bosakova, Michaela, Abraham, Sara P, Nita, Alexandru, Hruba, Eva, Buchtova, Marcela, Taylor, S Paige, Duran, Ivan, Martin, Jorge, Svozilova, Katerina, Barta, Tomas, Varecha, Miroslav, Balek, Lukas, Kohoutek, Jiri, Radaszkiewicz, Tomasz, Pusapati, Ganesh V, Bryja, Vitezslav, Rush, Eric T, Thiffault, Isabelle, Nickerson, Deborah A, Bamshad, Michael J, Rohatgi, Rajat, Cohn, Daniel H, Krakow, Deborah, Krejci, Pavel
Publicado 2020