Population Pharmacokinetics of Heptanoate in Healthy Subjects and Patients With Long‐Chain Fatty Acid Oxidation Disorders Treated With Triheptanoin

por Lee, Sun Ku, Gosselin, Nathalie H., Jomphe, Claudia, McKeever, Kathleen, Putnam, Wendy
Publicado 2022

A Pharmacokinetic Bioequivalence Study Comparing Pirfenidone Tablet and Capsule Dosage Forms in Healthy Adult Volunteers

por Pan, Lin, Belloni, Paula, Ding, Han Ting, Wang, Jianshuang, Rubino, Christopher M., Putnam, Wendy S.
Publicado 2017

Comparability Considerations and Challenges for Expedited Development Programs for Biological Products

por Schrieber, Sarah J., Putnam, Wendy S., Chow, Edwin Chiu Yuen, Cieslak, Jacek, Zhuang, Yanli, Martin, Steven W., Hanson, Paul, Maggio, Frank, Rosado, Leslie A. Rivera
Publicado 2020

Population Pharmacokinetics and Exposure‐Response Relationships of Astegolimab in Patients With Severe Asthma

por Kotani, Naoki, Dolton, Michael, Svensson, Robin J., Ribbing, Jakob, Friberg, Lena E., Vadhavkar, Shweta, Cheung, Dorothy, Staton, Tracy, Sperinde, Gizette, Jin, Jin, Putnam, Wendy S., Quartino, Angelica
Publicado 2022

Efficacy, safety, and tolerability of lebrikizumab in adolescent patients with uncontrolled asthma (ACOUSTICS)

por Szefler, Stanley J., Roberts, Graham, Rubin, Adalberto S., Zielen, Stefan, Kuna, Piotr, Alpan, Oral, Anzures‐Cabrera, Judith, Chen, Qiang, Holweg, Cécile T. J., Kaminski, Janusz, Putnam, Wendy S., Matthews, John G., Kamath, Nikhil
Publicado 2022

Population repeated time‐to‐event analysis of exacerbations in asthma patients: A novel approach for predicting asthma exacerbations based on biomarkers, spirometry, and diaries/qu...

por Svensson, Robin J, Ribbing, Jakob, Kotani, Naoki, Dolton, Michael, Vadhavkar, Shweta, Cheung, Dorothy, Staton, Tracy, Choy, David F, Putnam, Wendy, Jin, Jin, Budha, Nageshwar, Karlsson, Mats O., Quartino, Angelica, Zhu, Rui
Publicado 2021

Translational and pharmacokinetic‐pharmacodynamic application for the clinical development of GDC‐0334, a novel TRPA1 inhibitor

por Chan, Phyllis, Ding, Han Ting, Liederer, Bianca M., Mao, Jialin, Belloni, Paula, Chen, Liuxi, Gao, Simon S., Joseph, Victory, Yang, Xiaoying, Lin, Joseph S., Mitra, Mayur S., Putnam, Wendy S., Quartino, Angelica, Bauer, Rebecca N., Pan, Lin
Publicado 2021

Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies

por Hanania, Nicola A, Noonan, Michael, Corren, Jonathan, Korenblat, Phillip, Zheng, Yanan, Fischer, Saloumeh K, Cheu, Melissa, Putnam, Wendy S, Murray, Elaine, Scheerens, Heleen, Holweg, Cecile TJ, Maciuca, Romeo, Gray, Sarah, Doyle, Ramona, McClintock, Dana, Olsson, Julie, Matthews, John G, Yen, Karl
Publicado 2015

A randomized, placebo‐controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER)

por Austin, Cary D., Gonzalez Edick, Melissa, Ferrando, Ronald E., Solon, Margaret, Baca, Miriam, Mesh, Kathryn, Bradding, Peter, Gauvreau, Gail M., Sumino, Kaharu, FitzGerald, J. Mark, Israel, Elliot, Bjermer, Lief, Bourdin, Arnaud, Arron, Joseph R., Choy, David F., Olsson, Julie K., Abreu, Francis, Howard, Monet, Wong, Kit, Cai, Fang, Peng, Kun, Putnam, Wendy S., Holweg, Cécile T.J., Matthews, John G., Kraft, Monica, Woodruff, Prescott G.
Publicado 2020