Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response

por Alzabin, Saba, Pyarajan, Saiju, Yee, Herman, Kiefer, Friedemann, Suzuki, Akira, Burakoff, Steven, Sawasdikosol, Sansana
Publicado 2009

From Bytes to Bedside: Data Integration and Computational Biology for Translational Cancer Research

por Mathew, Jomol P, Taylor, Barry S, Bader, Gary D, Pyarajan, Saiju, Antoniotti, Marco, Chinnaiyan, Arul M, Sander, Chris, Burakoff, Steven J, Mishra, Bud
Publicado 2007

The VA Point-of-Care Precision Oncology Program: Balancing Access with Rapid Learning in Molecular Cancer Medicine

por Fiore, Louis D., Brophy, Mary T., Turek, Sara, Kudesia, Valmeek, Ramnath, Nithya, Shannon, Colleen, Ferguson, Ryan, Pyarajan, Saiju, Fiore, Melissa A., Hornberger, John, Lavori, Philip
Publicado 2016

Pharmacogenetic allele variant frequencies: An analysis of the VA’s Million Veteran Program (MVP) as a representation of the diversity in US population

por Markianos, Kyriacos, Dong, Frederic, Gorman, Bryan, Shi, Yunling, Dochtermann, Daniel, Saxena, Uma, Devineni, Poornima, Moser, Jennifer, Muralidhar, Sumitra, Ramoni, Rachel, Tsao, Philip, Pyarajan, Saiju, Przygodzki, Ronald
Publicado 2023

Gene–Toxicant Interactions in Gulf War Illness: Differential Effects of the PON1 Genotype

por Vahey, Jacqueline, Gifford, Elizabeth J., Sims, Kellie J., Chesnut, Blair, Boyle, Stephen H., Stafford, Crystal, Upchurch, Julie, Stone, Annjanette, Pyarajan, Saiju, Efird, Jimmy T., Williams, Christina D., Hauser, Elizabeth R.
Publicado 2021

S173. GENOME-WIDE ASSOCIATION STUDIES OF SCHIZOPHRENIA AND BIPOLAR DISORDER IN A DIVERSE COHORT OF US VETERANS

por Bigdeli, Tim, Fanous, Ayman, Rajeevan, Nallakkandi, Sayward, Frederick, Li, Yuli, Brophy, Mary, Pyarajan, Saiju, Gleason, Theresa, Przygodszki, Ronald, Gaziano, Michael, O’Leary, Timothy, Muralidhar, Sumitra, Huang, Grant, Concato, John, Siever, Larry, Aslan, Mihaela, Harvey, Philip
Publicado 2020

Admixture mapping of peripheral artery disease in a Dominican population reveals a putative risk locus on 2q35

por Cullina, Sinead, Wojcik, Genevieve L., Shemirani, Ruhollah, Klarin, Derek, Gorman, Bryan R., Sorokin, Elena P., Gignoux, Christopher R., Belbin, Gillian M., Pyarajan, Saiju, Asgari, Samira, Tsao, Philip S., Damrauer, Scott M., Abul-Husn, Noura S., Kenny, Eimear E.
Publicado 2023

Multi-ancestry GWAS of Fuchs corneal dystrophy highlights roles of laminins, collagen, and endothelial cell regulation

por Peachey, Neal, Gorman, Bryan, Francis, Michael, Nealon, Cari, Halladay, Christopher, Duro, Nalvi, Markianos, Kyriacos, Genovese, Giulio, Hysi, Pirro, Choquet, Hélène, Afshari, Natalie, Li, Yi-Ju, Gaziano, J. Michael, Hung, Adriana, Wu, Wen-Chih, Greenberg, Paul, Pyarajan, Saiju, Lass, Jonathan, Iyengar, Sudha
Publicado 2023

Immunogenetic Determinants of Susceptibility to Head and Neck Cancer in the Million Veteran Program Cohort

por Liu, Yanhong, Kramer, Jennifer R., Sandulache, Vlad C., Yu, Robert, Li, Guojun, Chen, Liang, Yusuf, Zenab I., Shi, Yunling, Pyarajan, Saiju, Tsavachidis, Spyros, Jiao, Li, Mierzwa, Michelle L., Chiao, Elizabeth, Mowery, Yvonne M., Shuman, Andrew, Shete, Sanjay, Sikora, Andrew G., White, Donna L.
Publicado 2023

CXCL12 regulates coronary artery dominance in diverse populations and links development to disease

por Rios Coronado, Pamela E, Zanetti, Daniela, Zhou, Jiayan, Naftaly, Jeffrey A, Prabala, Pratima, Kho, Pik Fang, Martínez Jaimes, Azalia M, Hilliard, Austin T, Pyarajan, Saiju, Dochtermann, Daniel, Chang, Kyong-Mi, Winn, Virginia D, Pașca, Anca M, Plomondon, Mary E, Waldo, Stephen W, Tsao, Philip S, Clarke, Shoa L., Red-Horse, Kristy, Assimes, Themistocles L.
Publicado 2023

Baseline Characterization and Annual Trends of Body Mass Index for a Mega-Biobank Cohort of US Veterans 2011–2017

por Nguyen, Xuan-Mai T., Quaden, Rachel M., Song, Rebecca J., Ho, Yuk-Lam, Honerlaw, Jacqueline, Whitbourne, Stacey, DuVall, Scott L., Deen, Jennifer, Pyarajan, Saiju, Moser, Jennifer, Huang, Grant D., Muralidhar, Sumitra, Concato, John, Tsao, Philip S., O’Donnell, Christopher J., Wilson, Peter W. F., Djousse, Luc, Gagnon, David R., Gaziano, J. Michael, Cho, Kelly
Publicado 2018

Modeling the longitudinal changes of ancestry diversity in the Million Veteran Program

por Wendt, Frank R., Pathak, Gita A., Vahey, Jacqueline, Qin, Xuejun, Koller, Dora, Cabrera-Mendoza, Brenda, Haeny, Angela, Harrington, Kelly M., Rajeevan, Nallakkandi, Duong, Linh M., Levey, Daniel F., De Angelis, Flavio, De Lillo, Antonella, Bigdeli, Tim B., Pyarajan, Saiju, Gaziano, John Michael, Gelernter, Joel, Aslan, Mihaela, Provenzale, Dawn, Helmer, Drew A., Hauser, Elizabeth R., Polimanti, Renato
Publicado 2023

A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program

por Raghavan, Sridharan, Huang, Jie, Tcheandjieu, Catherine, Huffman, Jennifer E., Litkowski, Elizabeth, Liu, Chang, Ho, Yuk-Lam A., Hunter-Zinck, Haley, Zhao, Hongyu, Marouli, Eirini, North, Kari E., Lange, Ethan, Lange, Leslie A., Voight, Benjamin F., Gaziano, J. Michael, Pyarajan, Saiju, Hauser, Elizabeth R., Tsao, Philip S., Wilson, Peter W. F., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Sun, Yan V., Assimes, Themistocles L.
Publicado 2022

Phenome-wide association of 1809 phenotypes and COVID-19 disease progression in the Veterans Health Administration Million Veteran Program

por Song, Rebecca J., Ho, Yuk-Lam, Schubert, Petra, Park, Yojin, Posner, Daniel, Lord, Emily M., Costa, Lauren, Gerlovin, Hanna, Kurgansky, Katherine E., Anglin-Foote, Tori, DuVall, Scott, Huffman, Jennifer E., Pyarajan, Saiju, Beckham, Jean C., Chang, Kyong-Mi, Liao, Katherine P., Djousse, Luc, Gagnon, David R., Whitbourne, Stacey B., Ramoni, Rachel, Muralidhar, Sumitra, Tsao, Philip S., O’Donnell, Christopher J., Gaziano, John Michael, Casas, Juan P., Cho, Kelly
Publicado 2021

Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program

por Serper, Marina, Vujkovic, Marijana, Kaplan, David E., Carr, Rotonya M., Lee, Kyung Min, Shao, Qing, Miller, Donald R., Reaven, Peter D., Phillips, Lawrence S., O’Donnell, Christopher J., Meigs, James B., Wilson, Peter W. F., Vickers-Smith, Rachel, Kranzler, Henry R., Justice, Amy C., Gaziano, John M., Muralidhar, Sumitra, Pyarajan, Saiju, DuVall, Scott L., Assimes, Themistocles L., Lee, Jennifer S., Tsao, Philip S., Rader, Daniel J., Damrauer, Scott M., Lynch, Julie A., Saleheen, Danish, Voight, Benjamin F., Chang, Kyong-Mi
Publicado 2020

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program

por Verma, Anurag, Tsao, Noah, Thomann, Lauren, Ho, Yuk-Lam, Iyengar, Sudha, Luoh, Shiuh-Wen, Carr, Rotonya, Crawford, Dana, Efird, Jimmy T., Huffman, Jennifer, Hung, Adriana, Ivey, Kerry, Levin, Michael, Lynch, Julie, Natarajan, Pradeep, Pyarajan, Saiju, Bick, Alexander, Costa, Lauren, Genovese, Giulio, Hauger, Richard, Madduri, Ravi, Pathak, Gita, Polimanti, Renato, Voight, Benjamin, Vujkovic, Marijana, Zekavat, Maryam, Zhao, Hongyu, Ritchie, Marylyn D, Chang, Kyong-Mi, Cho, Kelly, Casas, Juan P., Tsao, Philip S., Gaziano, J. Michael, O’Donnell, Christopher, Damrauer, Scott, Liao, Katherine
Publicado 2021

Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia, Bipolar Disorder, and Depression Among Adults in the US Veterans Affairs Health Care System

por Bigdeli, Tim B., Voloudakis, Georgios, Barr, Peter B., Gorman, Bryan R., Genovese, Giulio, Peterson, Roseann E., Burstein, David E., Velicu, Vlad I., Li, Yuli, Gupta, Rishab, Mattheisen, Manuel, Tomasi, Simone, Rajeevan, Nallakkandi, Sayward, Frederick, Radhakrishnan, Krishnan, Natarajan, Sundar, Malhotra, Anil K., Shi, Yunling, Zhao, Hongyu, Kosten, Thomas R., Concato, John, O’Leary, Timothy J., Przygodzki, Ronald, Gleason, Theresa, Pyarajan, Saiju, Brophy, Mary, Huang, Grant D., Muralidhar, Sumitra, Gaziano, J. Michael, Aslan, Mihaela, Fanous, Ayman H., Harvey, Philip D., Roussos, Panos
Publicado 2022

Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder

por Bigdeli, Tim B., Barr, Peter B., Rajeevan, Nallakkandi, Graham, David P., Li, Yuli, Meyers, Jacquelyn L., Gorman, Bryan R., Peterson, Roseann E., Sayward, Frederick, Radhakrishnan, Krishnan, Natarajan, Sundar, Nielsen, David A., Wilkinson, Anna V., Malhotra, Anil K., Zhao, Hongyu, Brophy, Mary, Shi, Yunling, O’Leary, Timothy J., Gleason, Theresa, Przygodzki, Ronald, Pyarajan, Saiju, Muralidhar, Sumitra, Gaziano, J. Michael, Huang, Grant D., Concato, John, Siever, Larry J., DeLisi, Lynn E., Kimbrel, Nathan A., Beckham, Jean C., Swann, Alan C., Kosten, Thomas R., Fanous, Ayman H., Aslan, Mihaela, Harvey, Philip D.
Publicado 2023

Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program

por Klarin, Derek, Devineni, Poornima, Sendamarai, Anoop K., Angueira, Anthony R., Graham, Sarah E., Shen, Ying H., Levin, Michael G., Pirruccello, James P., Surakka, Ida, Karnam, Purushotham R., Roychowdhury, Tanmoy, Li, Yanming, Wang, Minxian, Aragam, Krishna G., Paruchuri, Kaavya, Zuber, Verena, Shakt, Gabrielle E., Tsao, Noah L., Judy, Renae L., Vy, Ha My T., Verma, Shefali S., Rader, Daniel J., Do, Ron, Bavaria, Joseph E., Nadkarni, Girish N., Ritchie, Marylyn D., Burgess, Stephen, Guo, Dong-chuan, Ellinor, Patrick T., LeMaire, Scott A., Milewicz, Dianna M., Willer, Cristen J., Natarajan, Pradeep, Tsao, Philip S., Pyarajan, Saiju, Damrauer, Scott M.
Publicado 2023

Inherited myeloproliferative neoplasm risk impacts hematopoietic stem cells

por Bao, Erik L., Nandakumar, Satish K., Liao, Xiaotian, Bick, Alexander G., Karjalainen, Juha, Tabaka, Marcin, Gan, Olga I., Havulinna, Aki, Kiiskinen, Tuomo, Lareau, Caleb A., de Lapuente Portilla, Aitzkoa Lopez, Li, Bo, Emdin, Connor, Codd, Veryan, Nelson, Christopher P., Walker, Christopher J., Churchhouse, Claire, de la Chapelle, Albert, Klein, Daryl E., Nilsson, Björn, Wilson, Peter W.F., Cho, Kelly, Pyarajan, Saiju, Gaziano, J. Michael, Samani, Nilesh J., Regev, Aviv, Palotie, Aarno, Neale, Benjamin M., Dick, John E., Natarajan, Pradeep, O’Donnell, Christopher J., Daly, Mark J., Milyavsky, Michael, Kathiresan, Sekar, Sankaran, Vijay G.
Publicado 2020