Prediction of drug side effects with transductive matrix co-completion

por Liang, Xujun, Fu, Ying, Qu, Lingzhi, Zhang, Pengfei, Chen, Yongheng
Publicado 2023

IMF: Interpretable Multi-Hop Forecasting on Temporal Knowledge Graphs

por Du, Zhenyu, Qu, Lingzhi, Liang, Zongwei, Huang, Keju, Cui, Lin, Gao, Zhiyang
Publicado 2023

Comprehensive analysis of necroptosis-related lncRNA signature with potential implications in tumor heterogeneity and prediction of prognosis in clear cell renal cell carcinoma

por Lin, Hang, Qu, Lingzhi, Chen, Guanqiu, Zhang, Chunfang, Lu, Liqing, Chen, Yongheng
Publicado 2023

Learning important features from multi-view data to predict drug side effects

por Liang, Xujun, Zhang, Pengfei, Li, Jun, Fu, Ying, Qu, Lingzhi, Chen, Yongheng, Chen, Zhuchu
Publicado 2019

Characterization of the cholangiocarcinoma drug pemigatinib against FGFR gatekeeper mutants

por Lin, Qianmeng, Chen, Xiaojuan, Qu, Lingzhi, Guo, Ming, Wei, Hudie, Dai, Shuyan, Jiang, Longying, Chen, Yongheng
Publicado 2022

Structural insight into the ligand binding mechanism of aryl hydrocarbon receptor

por Dai, Shuyan, Qu, Lingzhi, Li, Jun, Zhang, Ye, Jiang, Longying, Wei, Hudie, Guo, Ming, Chen, Xiaojuan, Chen, Yongheng
Publicado 2022

Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors

por Qu, Lingzhi, Chen, Xiaojuan, Wei, Hudie, Guo, Ming, Dai, Shuyan, Jiang, Longying, Li, Jun, Yue, Sitong, Chen, Zhuchu, Chen, Yongheng
Publicado 2022

Crystal Structure of the FGFR4/LY2874455 Complex Reveals Insights into the Pan-FGFR Selectivity of LY2874455

por Wu, Daichao, Guo, Ming, Philips, Michael A., Qu, Lingzhi, Jiang, Longying, Li, Jun, Chen, Xiaojuan, Chen, Zhuchu, Chen, Lin, Chen, Yongheng
Publicado 2016

Structural basis for DNA recognition by FOXC2

por Chen, Xiaojuan, Wei, Hudie, Li, Jun, Liang, Xujun, Dai, Shuyan, Jiang, Longying, Guo, Ming, Qu, Lingzhi, Chen, Zhuchu, Chen, Lin, Chen, Yongheng
Publicado 2019

Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity

por Wei, Hudie, Wang, Haolan, Wang, Genxin, Qu, Lingzhi, Jiang, Longying, Dai, Shuyan, Chen, Xiaojuan, Zhang, Ye, Chen, Zhuchu, Li, Youjun, Guo, Ming, Chen, Yongheng
Publicado 2023

Mechanism of forkhead transcription factors binding to a novel palindromic DNA site

por Li, Jun, Dai, Shuyan, Chen, Xiaojuan, Liang, Xujun, Qu, Lingzhi, Jiang, Longying, Guo, Ming, Zhou, Zhan, Wei, Hudie, Zhang, Huajun, Chen, Zhuchu, Chen, Lin, Chen, Yongheng
Publicado 2021

Author Correction: Structure-based design of a dual-warhead covalent inhibitor of FGFR4

por Chen, Xiaojuan, Li, Huiliang, Lin, Qianmeng, Dai, Shuyan, Yue, Sitong, Qu, Lingzhi, Li, Maoyu, Guo, Ming, Wei, Hudie, Li, Jun, Jiang, Longying, Xu, Guangyu, Chen, Yongheng
Publicado 2022

Structure-based design of a dual-warhead covalent inhibitor of FGFR4

por Chen, Xiaojuan, Li, Huiliang, Lin, Qianmeng, Dai, Shuyan, Yue, Sitong, Qu, Lingzhi, Li, Maoyu, Guo, Ming, Wei, Hudie, Li, Jun, Jiang, Longying, Xu, Guangyu, Chen, Yongheng
Publicado 2022

Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis

por Wei, Hudie, Qu, Lingzhi, Dai, Shuyan, Li, Yun, Wang, Haolan, Feng, Yilu, Chen, Xiaojuan, Jiang, Longying, Guo, Ming, Li, Jun, Chen, Zhuchu, Chen, Lin, Zhang, Ye, Chen, Yongheng
Publicado 2021