Structural basis for the assembly of the type V CRISPR-associated transposon complex

por Schmitz, Michael, Querques, Irma, Oberli, Seraina, Chanez, Christelle, Jinek, Martin
Publicado 2022

Engineered Sleeping Beauty transposase redirects transposon integration away from genes

por Miskey, Csaba, Kesselring, Lisa, Querques, Irma, Abrusán, György, Barabas, Orsolya, Ivics, Zoltán
Publicado 2022

Publisher Correction: R-loop formation and conformational activation mechanisms of Cas9

por Pacesa, Martin, Loeff, Luuk, Querques, Irma, Muckenfuss, Lena M., Sawicka, Marta, Jinek, Martin
Publicado 2023

R-loop formation and conformational activation mechanisms of Cas9

por Pacesa, Martin, Loeff, Luuk, Querques, Irma, Muckenfuss, Lena M., Sawicka, Marta, Jinek, Martin
Publicado 2022

Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering

por Voigt, Franka, Wiedemann, Lisa, Zuliani, Cecilia, Querques, Irma, Sebe, Attila, Mátés, Lajos, Izsvák, Zsuzsanna, Ivics, Zoltán, Barabas, Orsolya
Publicado 2016

A highly soluble Sleeping Beauty transposase improves control of gene insertion

por Querques, Irma, Mades, Andreas, Zuliani, Cecilia, Miskey, Csaba, Alb, Miriam, Grueso, Esther, Machwirth, Markus, Rausch, Tobias, Einsele, Hermann, Ivics, Zoltán, Hudecek, Michael, Barabas, Orsolya
Publicado 2019

A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming

por Kesselring, Lisa, Miskey, Csaba, Zuliani, Cecilia, Querques, Irma, Kapitonov, Vladimir, Laukó, Andrea, Fehér, Anita, Palazzo, Antonio, Diem, Tanja, Lustig, Janna, Sebe, Attila, Wang, Yongming, Dinnyés, András, Izsvák, Zsuzsanna, Barabas, Orsolya, Ivics, Zoltán
Publicado 2020