AARDVARK: an automated reversion detector for variants affecting resistance kinetics

por Moreno, Thaidy, Magana, Joaquin, Quigley, David A
Publicado 2023

Panx3 links body mass index and tumorigenesis in a genetically heterogeneous mouse model of carcinogen-induced cancer

por Halliwill, Kyle D., Quigley, David A., Kang, Hio Chung, Del Rosario, Reyno, Ginzinger, David, Balmain, Allan
Publicado 2016

Age, estrogen, and immune response in breast adenocarcinoma and adjacent normal tissue

por Quigley, David A., Tahiri, Andliena, Lüders, Torben, Riis, Margit H., Balmain, Allan, Børresen-Dale, Anne-Lise, Bukholm, Ida, Kristensen, Vessela
Publicado 2017

Network analysis of skin tumor progression identifies a rewired genetic architecture affecting inflammation and tumor susceptibility

por Quigley, David A, To, Minh D, Kim, Il Jin, Lin, Kevin K, Albertson, Donna G, Sjolund, Jonas, Pérez-Losada, Jesús, Balmain, Allan
Publicado 2011

Genetic architecture of murine skin inflammation and tumor susceptibility

por Quigley, David A., To, Minh D., Pérez-Losada, Jesús, Pelorosso, Facundo G., Mao, Jian-Hua, Nagase, Hiroki, Ginzinger, David G., Balmain, Allan
Publicado 2009

SV-HotSpot: detection and visualization of hotspots targeted by structural variants associated with gene expression

por Eteleeb, Abdallah M., Quigley, David A., Zhao, Shuang G., Pham, Duy, Yang, Rendong, Dehm, Scott M., Luo, Jingqin, Feng, Felix Y., Dang, Ha X., Maher, Christopher A.
Publicado 2020

Multiple Self-Healing Squamous Epithelioma (MSSE): rare variants in an adjacent region of chromosome 9q22.3 to known TGFBR1 mutations suggest a digenic or multilocus etiology

por Kang, Hio Chung, Quigley, David A., Kim, Il-Jin, Wakabayashi, Yuichi, Ferguson-Smith, Malcolm A, D’Alessandro, Mariella, Lane, E Birgitte, Akhurst, Rosemary J., Goudie, David R, Balmain, Allan
Publicado 2013

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer

por Westcott, Peter M. K., Halliwill, Kyle D., To, Minh D., Rashid, Mamunur, Rust, Alistair G., Keane, Thomas M., Delrosario, Reyno, Jen, Kuang-Yu, Gurley, Kay E., Kemp, Christopher J., Fredlund, Erik, Quigley, David A., Adams, David J., Balmain, Allan
Publicado 2014

A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS

por McMahon, Mary, Contreras, Adrian, Holm, Mikael, Uechi, Tamayo, Forester, Craig M, Pang, Xiaming, Jackson, Cody, Calvert, Meredith E, Chen, Bin, Quigley, David A, Luk, John M, Kelley, R Kate, Gordan, John D, Gill, Ryan M, Blanchard, Scott C, Ruggero, Davide
Publicado 2019

An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer

por Das, Rajdeep, Sjöström, Martin, Shrestha, Raunak, Yogodzinski, Christopher, Egusa, Emily A., Chesner, Lisa N., Chen, William S., Chou, Jonathan, Dang, Donna K., Swinderman, Jason T., Ge, Alex, Hua, Junjie T., Kabir, Shaheen, Quigley, David A., Small, Eric J., Ashworth, Alan, Feng, Felix Y., Gilbert, Luke A.
Publicado 2021

Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry

por Gonzalez, Veronica D., Samusik, Nikolay, Chen, Tiffany J., Savig, Erica S., Aghaeepour, Nima, Quigley, David A., Huang, Ying-Wen, Giangarrà, Valeria, Borowsky, Alexander D., Hubbard, Neil E., Chen, Shih-Yu, Han, Guojun, Ashworth, Alan, Kipps, Thomas J., Berek, Jonathan S., Nolan, Garry P., Fantl, Wendy J.
Publicado 2018

Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic tel...

por Letteboer, Tom G. W., Benzinou, Michael, Merrick, Christopher B., Quigley, David A., Zhau, Kechen, Kim, Il-Jin, To, Minh D., Jablons, David M., van Amstel, Johannes K. P., Westermann, Cornelius J. J., Giraud, Sophie, Dupuis-Girod, Sophie, Lesca, Gaetan, Berg, Jonathan H., Balmain, Allan, Akhurst, Rosemary J.
Publicado 2015

Predicting cancer drug TARGETS - TreAtment Response Generalized Elastic-neT Signatures

por Rydzewski, Nicholas R., Peterson, Erik, Lang, Joshua M., Yu, Menggang, Laura Chang, S., Sjöström, Martin, Bakhtiar, Hamza, Song, Gefei, Helzer, Kyle T., Bootsma, Matthew L., Chen, William S., Shrestha, Raunak M., Zhang, Meng, Quigley, David A., Aggarwal, Rahul, Small, Eric J., Wahl, Daniel R., Feng, Felix Y., Zhao, Shuang G.
Publicado 2021

Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3(VNTR) polymorphisms and gene co-expression

por Fores-Martos, Jaume, Cervera-Vidal, Raimundo, Sierra-Roca, Julia, Lozano-Asencio, Carlos, Fedele, Vita, Cornelissen, Sten, Edvarsen, Hege, Tadeo-Cervera, Irene, Eroles, Pilar, Lluch, Ana, Tabares-Seisdedos, Rafa, Falcó, Antonio, Van’t Veer, Laura J., Schmidt, Marjanka, Quigley, David A., Børresen-Dale, Anne-Lise, Kristensen, Vessela N., Balmain, Allan, Climent, Joan
Publicado 2021

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

por Campbell, James, Ryan, Colm J., Brough, Rachel, Bajrami, Ilirjana, Pemberton, Helen N., Chong, Irene Y., Costa-Cabral, Sara, Frankum, Jessica, Gulati, Aditi, Holme, Harriet, Miller, Rowan, Postel-Vinay, Sophie, Rafiq, Rumana, Wei, Wenbin, Williamson, Chris T., Quigley, David A., Tym, Joe, Al-Lazikani, Bissan, Fenton, Timothy, Natrajan, Rachael, Strauss, Sandra J., Ashworth, Alan, Lord, Christopher J.
Publicado 2016

Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer

por Sayar, Erolcan, Patel, Radhika A., Coleman, Ilsa M., Roudier, Martine P., Zhang, Ailin, Mustafi, Pallabi, Low, Jin-Yih, Hanratty, Brian, Ang, Lisa S., Bhatia, Vipul, Adil, Mohamed, Bakbak, Hasim, Quigley, David A., Schweizer, Michael T., Hawley, Jessica E., Kollath, Lori, True, Lawrence D., Feng, Felix Y., Bander, Neil H., Corey, Eva, Lee, John K., Morrissey, Colm, Gulati, Roman, Nelson, Peter S., Haffner, Michael C.
Publicado 2023

The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer

por Lundberg, Arian, Zhang, Meng, Aggarwal, Rahul, Li, Haolong, Zhang, Li, Foye, Adam, Sjöström, Martin, Chou, Jonathan, Chang, Kevin, Moreno-Rodriguez, Thaidy, Shrestha, Raunak, Baskin, Avi, Zhu, Xiaolin, Weinstein, Alana S., Younger, Noah, Alumkal, Joshi J., Beer, Tomasz M., Chi, Kim N., Evans, Christopher P., Gleave, Martin, Lara, Primo N., Reiter, Rob E., Rettig, Matthew B., Witte, Owen N., Wyatt, Alexander W., Feng, Felix Y., Small, Eric J., Quigley, David A.
Publicado 2023

CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer

por Ahmed, Musaddeque, Soares, Fraser, Xia, Ji-Han, Yang, Yue, Li, Jing, Guo, Haiyang, Su, Peiran, Tian, Yijun, Lee, Hyung Joo, Wang, Miranda, Akhtar, Nayeema, Houlahan, Kathleen E., Bosch, Almudena, Zhou, Stanley, Mazrooei, Parisa, Hua, Junjie T., Chen, Sujun, Petricca, Jessica, Zeng, Yong, Davies, Alastair, Fraser, Michael, Quigley, David A., Feng, Felix Y., Boutros, Paul C., Lupien, Mathieu, Zoubeidi, Amina, Wang, Liang, Walsh, Martin J., Wang, Ting, Ren, Shancheng, Wei, Gong-Hong, He, Housheng Hansen
Publicado 2021

Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance

por Alumkal, Joshi J., Sun, Duanchen, Lu, Eric, Beer, Tomasz M., Thomas, George V., Latour, Emile, Aggarwal, Rahul, Cetnar, Jeremy, Ryan, Charles J., Tabatabaei, Shaadi, Bailey, Shawna, Turina, Claire B., Quigley, David A., Guan, Xiangnan, Foye, Adam, Youngren, Jack F., Urrutia, Joshua, Huang, Jiaoti, Weinstein, Alana S., Friedl, Verena, Rettig, Matthew, Reiter, Robert E., Spratt, Daniel E., Gleave, Martin, Evans, Christopher P., Stuart, Joshua M., Chen, Yiyi, Feng, Felix Y., Small, Eric J., Witte, Owen N., Xia, Zheng
Publicado 2020

Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity

por Westbrook, Thomas C., Guan, Xiangnan, Rodansky, Eva, Flores, Diana, Liu, Chia Jen, Udager, Aaron M., Patel, Radhika A., Haffner, Michael C., Hu, Ya-Mei, Sun, Duanchen, Beer, Tomasz M., Foye, Adam, Aggarwal, Rahul, Quigley, David A., Youngren, Jack F., Ryan, Charles J., Gleave, Martin, Wang, Yuzhuo, Huang, Jiaoti, Coleman, Ilsa, Morrissey, Colm, Nelson, Peter S., Evans, Christopher P., Lara, Primo, Reiter, Robert E., Witte, Owen, Rettig, Matthew, Wong, Christopher K., Weinstein, Alana S., Uzunangelov, Vlado, Stuart, Josh M., Thomas, George V., Feng, Felix Y., Small, Eric J., Yates, Joel A., Xia, Zheng, Alumkal, Joshi J.
Publicado 2022