Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria

por Quintana-Cabrera, Rubén, Manjarrés-Raza, Israel, Vicente-Gutiérrez, Carlos, Corrado, Mauro, Bolaños, Juan P., Scorrano, Luca
Publicado 2021

γ-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor

por Quintana-Cabrera, Ruben, Fernandez-Fernandez, Seila, Bobo-Jimenez, Veronica, Escobar, Javier, Sastre, Juan, Almeida, Angeles, Bolaños, Juan P.
Publicado 2012

COX-2 Expression in Hepatocytes Improves Mitochondrial Function after Hepatic Ischemia-Reperfusion Injury

por Fuertes-Agudo, Marina, Luque-Tévar, María, Cucarella, Carme, Brea, Rocío, Boscá, Lisardo, Quintana-Cabrera, Rubén, Martín-Sanz, Paloma, Casado, Marta
Publicado 2022

PARP Inhibitor PJ34 Protects Mitochondria and Induces DNA-Damage Mediated Apoptosis in Combination With Cisplatin or Temozolomide in B16F10 Melanoma Cells

por Cseh, Anna Maria, Fabian, Zsolt, Quintana-Cabrera, Ruben, Szabo, Aliz, Eros, Krisztian, Soriano, Maria Eugenia, Gallyas, Ferenc, Scorrano, Luca, Sumegi, Balazs
Publicado 2019

Dysfunctional mitochondria accumulate in a skeletal muscle knockout model of Smn1, the causal gene of spinal muscular atrophy

por Chemello, Francesco, Pozzobon, Michela, Tsansizi, Lorenza Iolanda, Varanita, Tatiana, Quintana-Cabrera, Rubèn, Bonesso, Daniele, Piccoli, Martina, Lanfranchi, Gerolamo, Giacomello, Marta, Scorrano, Luca, Bean, Camilla
Publicado 2023

The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function

por Quintana-Cabrera, Rubén, Quirin, Charlotte, Glytsou, Christina, Corrado, Mauro, Urbani, Andrea, Pellattiero, Anna, Calvo, Enrique, Vázquez, Jesús, Enríquez, José Antonio, Gerle, Christoph, Soriano, María Eugenia, Bernardi, Paolo, Scorrano, Luca
Publicado 2018

Inhibition of autophagy curtails visual loss in a model of autosomal dominant optic atrophy

por Zaninello, Marta, Palikaras, Konstantinos, Naon, Deborah, Iwata, Keiko, Herkenne, Stephanie, Quintana-Cabrera, Ruben, Semenzato, Martina, Grespi, Francesca, Ross-Cisneros, Fred N., Carelli, Valerio, Sadun, Alfredo A., Tavernarakis, Nektarios, Scorrano, Luca
Publicado 2020

The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage

por Varanita, Tatiana, Soriano, Maria Eugenia, Romanello, Vanina, Zaglia, Tania, Quintana-Cabrera, Rubén, Semenzato, Martina, Menabò, Roberta, Costa, Veronica, Civiletto, Gabriele, Pesce, Paola, Viscomi, Carlo, Zeviani, Massimo, Di Lisa, Fabio, Mongillo, Marco, Sandri, Marco, Scorrano, Luca
Publicado 2015

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

por Cogliati, Sara, Frezza, Christian, Soriano, Maria Eugenia, Varanita, Tatiana, Quintana-Cabrera, Ruben, Corrado, Mauro, Cipolat, Sara, Costa, Veronica, Casarin, Alberto, Gomes, Ligia C., Perales-Clemente, Ester, Salviati, Leonardo, Fernandez-Silva, Patricio, Enriquez, Jose A., Scorrano, Luca
Publicado 2013

MFN2 mutations in Charcot–Marie–Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics

por Larrea, Delfina, Pera, Marta, Gonnelli, Adriano, Quintana–Cabrera, Rubén, Akman, H Orhan, Guardia-Laguarta, Cristina, Velasco, Kevin R, Area-Gomez, Estela, Dal Bello, Federica, De Stefani, Diego, Horvath, Rita, Shy, Michael E, Schon, Eric A, Giacomello, Marta
Publicado 2019

Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis

por Lopez-Fabuel, Irene, Garcia-Macia, Marina, Buondelmonte, Costantina, Burmistrova, Olga, Bonora, Nicolo, Alonso-Batan, Paula, Morant-Ferrando, Brenda, Vicente-Gutierrez, Carlos, Jimenez-Blasco, Daniel, Quintana-Cabrera, Ruben, Fernandez, Emilio, Llop, Jordi, Ramos-Cabrer, Pedro, Sharaireh, Aseel, Guevara-Ferrer, Marta, Fitzpatrick, Lorna, Thompton, Christopher D., McKay, Tristan R., Storch, Stephan, Medina, Diego L., Mole, Sara E., Fedichev, Peter O., Almeida, Angeles, Bolaños, Juan P.
Publicado 2022