An optimized NGS sample preparation protocol for in vitro CRISPR screens

por Wohlhieter, Corrin A., Uddin, Fathema, Quintanal-Villalonga, Àlvaro, Poirier, John T., Sen, Triparna, Rudin, Charles M.
Publicado 2021

Impact of Heat Shock Protein 90 Inhibition on the Proteomic Profile of Lung Adenocarcinoma as Measured by Two-Dimensional Electrophoresis Coupled with Mass Spectrometry

por Marrugal, Ángela, Ferrer, Irene, Pastor, Maria Dolores, Ojeda, Laura, Quintanal-Villalonga, Álvaro, Carnero, Amancio, Molina-Pinelo, Sonia, Paz-Ares, Luis
Publicado 2019

Identification of Predictive Biomarkers of Response to HSP90 Inhibitors in Lung Adenocarcinoma

por Marrugal, Ángela, Ferrer, Irene, Gómez-Sánchez, David, Quintanal-Villalonga, Álvaro, Pastor, María Dolores, Ojeda, Laura, Paz-Ares, Luis, Molina-Pinelo, Sonia
Publicado 2021

Histology-dependent prognostic role of pERK and p53 protein levels in early-stage non-small cell lung cancer

por Quintanal-Villalonga, Álvaro, Mediano, Mariló, Ferrer, Irene, Meléndez, Ricardo, Carranza-Carranza, Andrés, Suárez, Rocío, Carnero, Amancio, Molina-Pinelo, Sonia, Paz-Ares, Luis
Publicado 2018

A Six-Gene Prognostic and Predictive Radiotherapy-Based Signature for Early and Locally Advanced Stages in Non-Small-Cell Lung Cancer

por Peinado-Serrano, Javier, Quintanal-Villalonga, Álvaro, Muñoz-Galvan, Sandra, Verdugo-Sivianes, Eva M., Mateos, Juan C., Ortiz-Gordillo, María J., Carnero, Amancio
Publicado 2022

Inhibition of HSP90 in Driver Oncogene-Defined Lung Adenocarcinoma Cell Lines: Key Proteins Underpinning Therapeutic Efficacy

por Marrugal, Ángela, Ferrer, Irene, Quintanal-Villalonga, Álvaro, Ojeda, Laura, Pastor, María Dolores, García-Luján, Ricardo, Carnero, Amancio, Paz-Ares, Luis, Molina-Pinelo, Sonia
Publicado 2023

MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma

por Ferrer, Irene, Quintanal-Villalonga, Álvaro, Molina-Pinelo, Sonia, Garcia-Heredia, Jose Manuel, Perez, Marco, Suárez, Rocío, Ponce-Aix, Santiago, Paz-Ares, Luis, Carnero, Amancio
Publicado 2018

The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction

por Quintanal-Villalonga, Álvaro, Ojeda-Márquez, Laura, Marrugal, Ángela, Yagüe, Patricia, Ponce-Aix, Santiago, Salinas, Ana, Carnero, Amancio, Ferrer, Irene, Molina-Pinelo, Sonia, Paz-Ares, Luis
Publicado 2018

Protocol to dissociate, process, and analyze the human lung tissue using single-cell RNA-seq

por Quintanal-Villalonga, Álvaro, Chan, Joseph M., Masilionis, Ignas, Gao, Vianne Ran, Xie, Yubin, Allaj, Viola, Chow, Andrew, Poirier, John T., Pe’er, Dana, Rudin, Charles M., Mazutis, Linas
Publicado 2022

FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy

por Quintanal-Villalonga, Álvaro, Ferrer, Irene, Guruceaga, Elizabeth, Cirauqui, Cristina, Marrugal, Ángela, Ojeda, Laura, García, Santiago, Zugazagoitia, Jon, Muñoz-Galván, Sandra, Lopez-Rios, Fernando, Montuenga, Luis, Vicent, Silvestre, Molina-Pinelo, Sonia, Carnero, Amancio, Paz-Ares, Luis
Publicado 2020

Coordinated downregulation of Spinophilin and the catalytic subunits of PP1, PPP1CA/B/C, contributes to a worse prognosis in lung cancer

por Verdugo-Sivianes, Eva M., Navas, Lola, Molina-Pinelo, Sonia, Ferrer, Irene, Quintanal-Villalonga, Alvaro, Peinado, Javier, Garcia-Heredia, Jose M., Felipe-Abrio, Blanca, Muñoz-Galvan, Sandra, Marin, Juan J., Montuenga, Luis, Paz-Ares, Luis, Carnero, Amancio
Publicado 2017

Rb Tumor Suppressor in Small Cell Lung Cancer: Combined Genomic and IHC Analysis with a Description of a Distinct Rb-Proficient Subset

por Febres-Aldana, Christopher A., Chang, Jason C., Ptashkin, Ryan, Wang, Yuhan, Gedvilaite, Erika, Baine, Marina K., Travis, William D., Ventura, Katia, Bodd, Francis, Yu, Helena A., Quintanal-Villalonga, Alvaro, Lai, W. Victoria, Egger, Jacklynn V., Offin, Michael, Ladanyi, Marc, Rudin, Charles M., Rekhtman, Natasha
Publicado 2022

Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer

por Wohlhieter, Corrin A., Richards, Allison L., Uddin, Fathema, Hulton, Christopher H., Quintanal-Villalonga, Àlvaro, Martin, Axel, de Stanchina, Elisa, Bhanot, Umeshkumar, Asher, Marina, Shah, Nisargbhai S., Hayatt, Omar, Buonocore, Darren J., Rekhtman, Natasha, Shen, Ronglai, Arbour, Kathryn C., Donoghue, Mark, Poirier, John T., Sen, Triparna, Rudin, Charles M.
Publicado 2020

Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies

por Glasner, Ariella, Rose, Samuel A., Sharma, Roshan, Gudjonson, Herman, Chu, Tinyi, Green, Jesse A., Rampersaud, Sham, Valdez, Izabella K., Andretta, Emma S., Dhillon, Bahawar S., Schizas, Michail, Dikiy, Stanislav, Mendoza, Alejandra, Hu, Wei, Wang, Zhong-Min, Chaudhary, Ojasvi, Xu, Tianhao, Mazutis, Linas, Rizzuto, Gabrielle, Quintanal-Villalonga, Alvaro, Manoj, Parvathy, de Stanchina, Elisa, Rudin, Charles M., Pe’er, Dana, Rudensky, Alexander Y.
Publicado 2023

Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation

por Quintanal-Villalonga, Alvaro, Taniguchi, Hirokazu, Zhan, Yingqian A., Hasan, Maysun M., Chavan, Shweta S., Meng, Fanli, Uddin, Fathema, Allaj, Viola, Manoj, Parvathy, Shah, Nisargbhai S., Chan, Joseph M., Ciampricotti, Metamia, Chow, Andrew, Offin, Michael, Ray-Kirton, Jordana, Egger, Jacklynn D., Bhanot, Umesh K., Linkov, Irina, Asher, Marina, Roehrl, Michael H., Ventura, Katia, Qiu, Juan, de Stanchina, Elisa, Chang, Jason C., Rekhtman, Natasha, Houck-Loomis, Brian, Koche, Richard P., Yu, Helena A., Sen, Triparna, Rudin, Charles M.
Publicado 2021