Nuclear envelope rupture drives genome instability in cancer

por Lim, Sanghee, Quinton, Ryan J., Ganem, Neil J.
Publicado 2016

A genome-wide microRNA screen identifies regulators of tetraploid cell proliferation

por Vittoria, Marc A., Shenk, Elizabeth M., O’Rourke, Kevin P., Bolgioni, Amanda F., Lim, Sanghee, Kacprzak, Victoria, Quinton, Ryan J., Ganem, Neil J.
Publicado 2018

Identification of the kinase STK25 as an upstream activator of LATS signaling

por Lim, Sanghee, Hermance, Nicole, Mudianto, Tenny, Mustaly, Hatim M., Mauricio, Ian Paolo Morelos, Vittoria, Marc A., Quinton, Ryan J., Howell, Brian W., Cornils, Hauke, Manning, Amity L., Ganem, Neil J.
Publicado 2019

S1P1 Threonine 236 Phosphorylation Mediates the Invasiveness of Triple-Negative Breast Cancer and Sensitivity to FTY720

por Laroche, Fabrice J. F., Li, Sheng, Shen, Ning, Hwang, Soo Kyung, Nguyen, Gina, Yu, Wenling, Wong, Chen Khuan, Quinton, Ryan J., Berman, Jason N., Liu, Ching-Ti, Singh, Anurag, Ganem, Neil J., Thiagalingam, Sam, Feng, Hui
Publicado 2023

Whole genome doubling confers unique genetic vulnerabilities on tumor cells

por Quinton, Ryan J., DiDomizio, Amanda, Vittoria, Marc A., Kotýnková, Kristýna, Ticas, Carlos J., Patel, Sheena, Koga, Yusuke, Vakhshoorzadeh, Jasmine, Hermance, Nicole, Kuroda, Taruho S., Parulekar, Neha, Taylor, Alison M., Manning, Amity L., Campbell, Joshua D., Ganem, Neil J.
Publicado 2021

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control

por Gan, Wenjian, Dai, Xiaoming, Dai, Xiangpeng, Xie, Jun, Yin, Shasha, Zhu, Junjie, Wang, Chen, Liu, Yuchen, Guo, Jianping, Wang, Min, Liu, Jing, Hu, Jia, Quinton, Ryan J., Ganem, Neil J., Liu, Pengda, Asara, John M., Pandolfi, Pier Paolo, Yang, Yingzi, He, Zhigang, Gao, Guangping, Wei, Wenyi
Publicado 2020