Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies

por Macarrón Palacios, Arturo, Grzeschik, Julius, Deweid, Lukas, Krah, Simon, Zielonka, Stefan, Rösner, Thies, Peipp, Matthias, Valerius, Thomas, Kolmar, Harald
Publicado 2020

Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy

por Klausz, Katja, Cieker, Michael, Kellner, Christian, Rösner, Thies, Otte, Anna, Krohn, Steffen, Lux, Anja, Nimmerjahn, Falk, Valerius, Thomas, Gramatzki, Martin, Peipp, Matthias
Publicado 2020

Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG

por Brandsma, Arianne M., Bondza, Sina, Evers, Mitchell, Koutstaal, Rosanne, Nederend, Maaike, Jansen, J. H. Marco, Rösner, Thies, Valerius, Thomas, Leusen, Jeanette H. W., ten Broeke, Toine
Publicado 2019

Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo

por Winterberg, Dorothee, Lenk, Lennart, Oßwald, Maren, Vogiatzi, Fotini, Gehlert, Carina Lynn, Frielitz, Fabian-Simon, Klausz, Katja, Rösner, Thies, Valerius, Thomas, Trauzold, Anna, Peipp, Matthias, Kellner, Christian, Schewe, Denis Martin
Publicado 2021

Enhancing CDC and ADCC of CD19 Antibodies by Combining Fc Protein-Engineering with Fc Glyco-Engineering

por Roßkopf, Sophia, Eichholz, Klara Marie, Winterberg, Dorothee, Diemer, Katarina Julia, Lutz, Sebastian, Münnich, Ira Alexandra, Klausz, Katja, Rösner, Thies, Valerius, Thomas, Schewe, Denis Martin, Humpe, Andreas, Gramatzki, Martin, Peipp, Matthias, Kellner, Christian
Publicado 2020

Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies

por Evers, Mitchell, Ten Broeke, Toine, Jansen, J.H. Marco, Nederend, Maaike, Hamdan, Firas, Reiding, Karli R., Meyer, Saskia, Moerer, Petra, Brinkman, Iris, Rösner, Thies, Lebbink, Robert Jan, Valerius, Thomas, Leusen, Jeanette H.W.
Publicado 2020

Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab

por Baumann, Niklas, Arndt, Christian, Petersen, Judith, Lustig, Marta, Rösner, Thies, Klausz, Katja, Kellner, Christian, Bultmann, Miriam, Bastian, Lorenz, Vogiatzi, Fotini, Leusen, Jeanette H. W., Burger, Renate, Schewe, Denis M., Peipp, Matthias, Valerius, Thomas
Publicado 2022

Enhancement of epidermal growth factor receptor antibody tumor immunotherapy by glutaminyl cyclase inhibition to interfere with CD47/signal regulatory protein alpha interactions

por Baumann, Niklas, Rösner, Thies, Jansen, J. H. Marco, Chan, Chilam, Marie Eichholz, Klara, Klausz, Katja, Winterberg, Dorothee, Müller, Kristina, Humpe, Andreas, Burger, Renate, Peipp, Matthias, Schewe, Denis M., Kellner, Christian, Leusen, Jeanette H. W., Valerius, Thomas
Publicado 2021

Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody

por Gehlert, Carina Lynn, Rahmati, Pegah, Boje, Ammelie Svea, Winterberg, Dorothee, Krohn, Steffen, Theocharis, Thomas, Cappuzzello, Elisa, Lux, Anja, Nimmerjahn, Falk, Ludwig, Ralf J., Lustig, Marta, Rösner, Thies, Valerius, Thomas, Schewe, Denis Martin, Kellner, Christian, Klausz, Katja, Peipp, Matthias
Publicado 2022

Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages

por Zeller, Tobias, Lutz, Sebastian, Münnich, Ira A., Windisch, Roland, Hilger, Patricia, Herold, Tobias, Tahiri, Natyra, Banck, Jan C., Weigert, Oliver, Moosmann, Andreas, von Bergwelt-Baildon, Michael, Flamann, Cindy, Bruns, Heiko, Wichmann, Christian, Baumann, Niklas, Valerius, Thomas, Schewe, Denis M., Peipp, Matthias, Rösner, Thies, Humpe, Andreas, Kellner, Christian
Publicado 2022

Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies by augmenting tumor cell phagocytosis

por Vogiatzi, Fotini, Heymann, Julia, Müller, Kristina, Winterberg, Dorothee, Drakul, Aneta, Rösner, Thies, Lenk, Lennart, Heib, Michelle, Gehlert, Carina Lynn, Cario, Gunnar, Schrappe, Martin, Claviez, Alexander, Bornhauser, Beat, Bourquin, Jean-Pierre, Bomken, Simon, Adam, Dieter, Frielitz, Fabian-Simon, Maecker-Kolhoff, Britta, Stanulla, Martin, Valerius, Thomas, Peipp, Matthias, Kellner, Christian, Schewe, Denis M.
Publicado 2022