Tissue turnover of collagen type I, III and elastin is elevated in the PCLS model of IPF and can be restored back to vehicle levels using a phosphodiesterase inhibitor

por Hansen, Niels Ulrik Brandt, Karsdal, Morten Asser, Brockbank, Sarah, Cruwys, Simon, Rønnow, Sarah, Leeming, Diana Julie
Publicado 2016

Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis

por Jessen, Henrik, Hoyer, Nils, Prior, Thomas S., Frederiksen, Peder, Rønnow, Sarah R., Karsdal, Morten A., Leeming, Diana J., Bendstrup, Elisabeth, Sand, Jannie M. B., Shaker, Saher B.
Publicado 2021

Type IV collagen turnover is predictive of mortality in COPD: a comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort

por Rønnow, Sarah Rank, Sand, Jannie Marie Bülow, Langholm, Lasse Løcke, Manon-Jensen, Tina, Karsdal, Morten Asser, Tal-Singer, Ruth, Miller, Bruce E., Vestbo, Jørgen, Leeming, Diana Julie
Publicado 2019

Increased von Willebrand Factor Processing in COPD, Reflecting Lung Epithelium Damage, Is Associated with Emphysema, Exacerbations and Elevated Mortality Risk

por Langholm, Lasse L, Rønnow, Sarah Rank, Sand, Jannie M B, Leeming, Diana Julie, Tal-Singer, Ruth, Miller, Bruce E, Vestbo, Jørgen, Karsdal, Morten A, Manon-Jensen, Tina
Publicado 2020

Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort

por Rønnow, Sarah R., Langholm, Lasse L., Karsdal, Morten A., Manon-Jensen, Tina, Tal-Singer, Ruth, Miller, Bruce E., Vestbo, Jørgen, Leeming, Diana J., Sand, Jannie M. B.
Publicado 2020

Combining biomarkers of clot resolution and alveolar basement membrane destruction predicts mortality in the ECLIPSE COPD cohort

por Sand, Jannie M.B., Rønnow, Sarah R., Langholm, Lasse L., Karsdal, Morten A., Manon-Jensen, Tina, Tal-Singer, Ruth, Miller, Bruce E., Vestbo, Jørgen, Leeming, Diana J.
Publicado 2020

Nintedanib modulates type III collagen turnover in viable precision-cut lung slices from bleomycin-treated rats and patients with pulmonary fibrosis

por Hesse, Christina, Beneke, Valerie, Konzok, Sebastian, Diefenbach, Claudia, Bülow Sand, Jannie Marie, Rønnow, Sarah Rank, Karsdal, Morten Asser, Jonigk, Danny, Sewald, Katherina, Braun, Armin, Leeming, Diana Julie, Wollin, Lutz
Publicado 2022

Specific elastin degradation products are associated with poor outcome in the ECLIPSE COPD cohort

por Rønnow, Sarah Rank, Langholm, Lasse Løcke, Sand, Jannie Marie Bülow, Thorlacius-Ussing, Jeppe, Leeming, Diana Julie, Manon-Jensen, Tina, Tal-Singer, Ruth, Miller, Bruce E., Karsdal, Morten Asser, Vestbo, Jørgen
Publicado 2019

Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis

por Rønnow, Sarah Rank, Dabbagh, Rand Qais, Genovese, Federica, Nanthakumar, Carmel B., Barrett, Vikki J., Good, Robert B., Brockbank, Sarah, Cruwys, Simon, Jessen, Henrik, Sorensen, Grith Lykke, Karsdal, Morten Asser, Leeming, Diana Julie, Sand, Jannie Marie Bülow
Publicado 2020

A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype

por Rønnow, Sarah Rank, Sand, Jannie Marie Bülow, Staunstrup, Line Mærsk, Bahmer, Thomas, Wegmann, Michael, Lunding, Lars, Burgess, Janette, Rabe, Klaus, Sorensen, Grith Lykke, Fuchs, Oliver, Mutius, Erika V., Hansen, Gesine, Kopp, Matthias Volkmar, Karsdal, Morten, Leeming, Diana Julie, Weckmann, Markus
Publicado 2022

Biomarkers of Clot Activation and Degradation and Risk of Future Major Cardiovascular Events in Acute Exacerbation of COPD: A Cohort Sub-Study in a Randomized Trial Population

por Kamstrup, Peter, Sand, Jannie Marie Bülow, Ulrik, Charlotte Suppli, Janner, Julie, Rønn, Christian Philip, Rønnow, Sarah Rank, Leeming, Diana Julie, Jensen, Sidse Graff, Wilcke, Torgny, Mathioudakis, Alexander G., Miravitlles, Marc, Lapperre, Therese, Bendstrup, Elisabeth, Frikke-Schmidt, Ruth, Murray, Daniel D., Itenov, Theis, Bossios, Apostolos, Nielsen, Susanne Dam, Vestbo, Jørgen, Biering-Sørensen, Tor, Karsdal, Morten, Jensen, Jens-Ulrik, Sivapalan, Pradeesh
Publicado 2022