Deficient mismatch repair: Read all about it (Review)

por RICHMAN, SUSAN
Publicado 2015

How close are we to standardised extended RAS gene mutation testing? The UK NEQAS evaluation

por Richman, Susan D, Fairley, Jennifer, Butler, Rachel, Deans, Zandra C
Publicado 2017

RAS screening in colorectal cancer: a comprehensive analysis of the results from the UK NEQAS colorectal cancer external quality assurance schemes (2009–2016)

por Richman, Susan D., Fairley, Jennifer, Butler, Rachel, Deans, Zandra C.
Publicado 2017

Acute Ovarian Insufficiency and Uterine Infarction Following Uterine Artery Embolization for Postpartum Hemorrhage

por Elsarrag, Sarah Z., Forss, Abigail R., Richman, Susan, Salih, Sana M.
Publicado 2015

Intra-tumoral Heterogeneity of KRAS and BRAF Mutation Status in Patients with Advanced Colorectal Cancer (aCRC) and Cost-Effectiveness of Multiple Sample Testing

por Richman, Susan D., Chambers, Philip, Seymour, Matthew T., Daly, Catherine, Grant, Sophie, Hemmings, Gemma, Quirke, Philip
Publicado 2011

Results of the UK NEQAS for Molecular Genetics reference sample analysis

por Richman, Susan D, Fairley, Jennifer, Hall, Jacqueline A, Nataraj, Nakul, Bhide, Mrudul, Lau, Aron, Norman, Kara L, Deans, Zandra C
Publicado 2018

Ultra-Low DNA Input into Whole Genome Methylation Assays and Detection of Oncogenic Methylation and Copy Number Variants in Circulating Tumour DNA

por Whalley, Celina, Payne, Karl, Domingo, Enric, Blake, Andrew, Richman, Susan, Brooks, Jill, Batis, Nikolaos, Spruce, Rachel, Mehanna, Hisham, Nankivell, Paul, Beggs, Andrew D.
Publicado 2021

Confirmation that somatic mutations of beta‐2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR...

por Barrow, Paul, Richman, Susan D, Wallace, Andrew J, Handley, Kelly, Hutchins, Gordon G A, Kerr, David, Magill, Laura, Evans, D Gareth, Gray, Richard, Quirke, Phil, Hill, James
Publicado 2019

Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial

por Richman, Susan D, Adams, Richard, Quirke, Phil, Butler, Rachel, Hemmings, Gemma, Chambers, Phil, Roberts, Helen, James, Michelle D, Wozniak, Sue, Bathia, Riya, Pugh, Cheryl, Maughan, Timothy, Jasani, Bharat
Publicado 2016

FOCUS4 biomarker laboratories: from the benefits to the practical and logistical issues faced during 6 years of centralised testing

por Richman, Susan D, Hemmings, Gemma, Roberts, Helen, Gallop, Niall, Dodds, Rachel, Wilkinson, Lyndsay, Davis, Jonathan, White, Rhian, Yates, Emma, Jasani, Bharat, Brown, Louise, Maughan, Tim S, Butler, Rachel, Quirke, Philip, Adams, Richard
Publicado 2023

Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial

por Adams, Richard, Brown, Ewan, Brown, Louise, Butler, Rachel, Falk, Stephen, Fisher, David, Kaplan, Richard, Quirke, Phil, Richman, Susan, Samuel, Leslie, Seligmann, Jenny, Seymour, Matt, Shiu, Kai Keen, Wasan, Harpreet, Wilson, Richard, Maughan, Tim
Publicado 2017

A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment

por Viratham Pulsawatdi, Amélie, Craig, Stephanie G., Bingham, Victoria, McCombe, Kris, Humphries, Matthew P., Senevirathne, Seedevi, Richman, Susan D., Quirke, Phil, Campo, Leticia, Domingo, Enric, Maughan, Timothy S., James, Jacqueline A., Salto‐Tellez, Manuel
Publicado 2020

Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone

por ten Hoorn, Sanne, Sommeijer, Dirkje W., Elliott, Faye, Fisher, David, de Back, Tim R., Trinh, Anne, Koens, Lianne, Maughan, Tim, Seligmann, Jenny, Seymour, Matthew T., Quirke, Phil, Adams, Richard, Richman, Susan D., Punt, Cornelis J. A., Vermeulen, Louis
Publicado 2021

Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer

por Brown, Louise C, Graham, Janet, Fisher, David, Adams, Richard, Seligmann, Jenny, Seymour, Matthew, Kaplan, Richard, Yates, Emma, Parmar, Mahesh, Richman, Susan D, Quirke, Philip, Butler, Rachel, Shiu, Kaikeen, Middleton, Gary, Samuel, Leslie, Wilson, Richard H, Maughan, Timothy S
Publicado 2022

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

por Dunne, Philip D., Alderdice, Matthew, O'Reilly, Paul G., Roddy, Aideen C., McCorry, Amy M. B., Richman, Susan, Maughan, Tim, McDade, Simon S., Johnston, Patrick G., Longley, Daniel B., Kay, Elaine, McArt, Darragh G., Lawler, Mark
Publicado 2017

Prospective patient stratification into robust cancer‐cell intrinsic subtypes from colorectal cancer biopsies

por Alderdice, Matthew, Richman, Susan D, Gollins, Simon, Stewart, James P, Hurt, Chris, Adams, Richard, McCorry, Amy MB, Roddy, Aideen C, Vimalachandran, Dale, Isella, Claudio, Medico, Enzo, Maughan, Tim, McArt, Darragh G, Lawler, Mark, Dunne, Philip D
Publicado 2018

Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA

por Dunwell, Thomas L., Dailey, Simon C., Ottestad, Anine L., Yu, Jihang, Becker, Philipp W., Scaife, Sarah, Richman, Susan D., Wood, Henry M., Slaney, Hayley, Bottomley, Daniel, Yang, Xiangsheng, Xiao, Hui, Wahl, Sissel G. F., Grønberg, Bjørn H., Dai, Hongyan, Fu, Guoliang
Publicado 2021

HER2 overexpression and amplification as a potential therapeutic target in colorectal cancer: analysis of 3256 patients enrolled in the QUASAR, FOCUS and PICCOLO colorectal cancer...

por Richman, Susan D, Southward, Katie, Chambers, Philip, Cross, Debra, Barrett, Jennifer, Hemmings, Gemma, Taylor, Morag, Wood, Henry, Hutchins, Gordon, Foster, Joseph M, Oumie, Assa, Spink, Karen G, Brown, Sarah R, Jones, Marc, Kerr, David, Handley, Kelly, Gray, Richard, Seymour, Matthew, Quirke, Philip
Publicado 2016

Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomi...

por Seymour, Matthew T, Brown, Sarah R, Middleton, Gary, Maughan, Timothy, Richman, Susan, Gwyther, Stephen, Lowe, Catherine, Seligmann, Jennifer F, Wadsley, Jonathan, Maisey, Nick, Chau, Ian, Hill, Mark, Dawson, Lesley, Falk, Stephen, O'Callaghan, Ann, Benstead, Kim, Chambers, Philip, Oliver, Alfred, Marshall, Helen, Napp, Vicky, Quirke, Phil
Publicado 2013

Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study

por Niehues, Jan Moritz, Quirke, Philip, West, Nicholas P., Grabsch, Heike I., van Treeck, Marko, Schirris, Yoni, Veldhuizen, Gregory P., Hutchins, Gordon G.A., Richman, Susan D., Foersch, Sebastian, Brinker, Titus J., Fukuoka, Junya, Bychkov, Andrey, Uegami, Wataru, Truhn, Daniel, Brenner, Hermann, Brobeil, Alexander, Hoffmeister, Michael, Kather, Jakob Nikolas
Publicado 2023