γ-synuclein is a novel player in the control of body lipid metabolism

por Millership, Steven, Ninkina, Natalia, Rochford, Justin J, Buchman, Vladimir L
Publicado 2013

Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet

por Mcilroy, George D., Mitchell, Sharon E., Han, Weiping, Delibegović, Mirela, Rochford, Justin J.
Publicado 2018

Ablation of Bscl2/seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

por Mcilroy, George D., Mitchell, Sharon E., Han, Weiping, Delibegović, Mirela, Rochford, Justin J.
Publicado 2020

Gene therapy restores adipose tissue and metabolic health in a pre-clinical mouse model of lipodystrophy

por Sommer, Nadine, Roumane, Ahlima, Han, Weiping, Delibegović, Mirela, Rochford, Justin J., Mcilroy, George D.
Publicado 2022

Neuroanatomical Characterisation of the Expression of the Lipodystrophy and Motor-Neuropathy Gene Bscl2 in Adult Mouse Brain

por Garfield, Alastair S., Chan, Wai S., Dennis, Rowena J., Ito, Daisuke, Heisler, Lora K., Rochford, Justin J.
Publicado 2012

Promethin Is a Conserved Seipin Partner Protein

por Castro, Inês G., Eisenberg-Bord, Michal, Persiani, Elisa, Rochford, Justin J., Schuldiner, Maya, Bohnert, Maria
Publicado 2019

The burden of metabolic syndrome on osteoarthritic joints

por Dickson, Bruce M., Roelofs, Anke J., Rochford, Justin J., Wilson, Heather M., De Bari, Cosimo
Publicado 2019

Temporal and Spatial Regulation of the Phosphatidate Phosphatases Lipin 1 and 2

por Grimsey, Neil, Han, Gil-Soo, O'Hara, Laura, Rochford, Justin J., Carman, George M., Siniossoglou, Symeon
Publicado 2008

Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

por Talukder, Md. Mesbah Uddin, Sim, M.F. Michelle, O'Rahilly, Stephen, Edwardson, J. Michael, Rochford, Justin J.
Publicado 2015

Bscl2 Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy

por Roumane, Ahlima, Mcilroy, George D., Balci, Arda, Han, Weiping, Delibegović, Mirela, Baldassarre, Massimiliano, Newsholme, Philip, Rochford, Justin J.
Publicado 2021

Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms

por Sim, M. F. Michelle, Talukder, M. Mesbah Uddin, Dennis, Rowena J., O’Rahilly, Stephen, Edwardson, J. Michael, Rochford, Justin J.
Publicado 2013

Knockdown of Diacylglycerol Kinase Delta Inhibits Adipocyte Differentiation and Alters Lipid Synthesis

por LOWE, Christopher E., ZHANG, Qifeng, DENNIS, Rowena J., AUBRY, Evelyne A., O’RAHILLY, Stephen, WAKELAM, Michael J.O., ROCHFORD, Justin J.
Publicado 2013

Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

por Sim, M. F. Michelle, Persiani, Elisa, Talukder, Md. Mesbah Uddin, Mcilroy, George D., Roumane, Ahlima, Edwardson, J. Michael, Rochford, Justin J.
Publicado 2020

The Human Lipodystrophy Gene BSCL2/Seipin May Be Essential for Normal Adipocyte Differentiation

por Payne, Victoria A., Grimsey, Neil, Tuthill, Antoinette, Virtue, Sam, Gray, Sarah L., Nora, Edoardo Dalla, Semple, Robert K., O'Rahilly, Stephen, Rochford, Justin J.
Publicado 2008

Phosphoprotein enriched in astrocytes (PEA)-15 is a novel regulator of adipose tissue expansion

por Verschoor, Pola J., Greig, Fiona H., Rochford, Justin J., Levate, Giovanni, Delibegovic, Mirela, Thompson, Dawn, Leeson-Payne, Alasdair, Dekeryte, Ruta, Banks, Ruth, Ramos, Joe W., Nixon, Graeme F.
Publicado 2021

Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

por Mcilroy, George D., Suchacki, Karla, Roelofs, Anke J., Yang, Wulin, Fu, Yanyun, Bai, Bo, Wallace, Robert J., De Bari, Cosimo, Cawthorn, William P., Han, Weiping, Delibegović, Mirela, Rochford, Justin J.
Publicado 2018

Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells

por Georgescu, Teodora, Lyons, David, Doslikova, Barbora, Garcia, Ana Paula, Marston, Oliver, Burke, Luke K, Chianese, Raffaella, Lam, Brian Y H, Yeo, Giles S H, Rochford, Justin J, Garfield, Alastair S, Heisler, Lora K
Publicado 2020

Nucleus of the Solitary Tract Serotonin 5-HT(2C) Receptors Modulate Food Intake

por D'Agostino, Giuseppe, Lyons, David, Cristiano, Claudia, Lettieri, Miriam, Olarte-Sanchez, Cristian, Burke, Luke K., Greenwald-Yarnell, Megan, Cansell, Celine, Doslikova, Barbora, Georgescu, Teodora, Martinez de Morentin, Pablo Blanco, Myers, Martin G., Rochford, Justin J., Heisler, Lora K.
Publicado 2018

Serotonin 2C Receptor Agonists Improve Type 2 Diabetes via Melanocortin-4 Receptor Signaling Pathways

por Zhou, Ligang, Sutton, Gregory M., Rochford, Justin J., Semple, Robert K., Lam, Daniel D., Oksanen, Laura J., Thornton-Jones, Zoe D., Clifton, Peter G., Yueh, Chen-Yu, Evans, Mark L., McCrimmon, Rory J., Elmquist, Joel K., Butler, Andrew A., Heisler, Lora K.
Publicado 2007

Lorcaserin improves glycemic control via a melanocortin neurocircuit

por Burke, Luke K., Ogunnowo-Bada, Emmanuel, Georgescu, Teodora, Cristiano, Claudia, de Morentin, Pablo B. Martinez, Valencia Torres, Lourdes, D'Agostino, Giuseppe, Riches, Christine, Heeley, Nicholas, Ruan, Yue, Rubinstein, Marcelo, Low, Malcolm J., Myers, Martin G., Rochford, Justin J., Evans, Mark L., Heisler, Lora K.
Publicado 2017