Drosophila as a model for unfolded protein response research

por Ryoo, Hyung Don
Publicado 2015

Two distinct nodes of translational inhibition in the Integrated Stress Response

por Ryoo, Hyung Don, Vasudevan, Deepika
Publicado 2017

Drosophila fabp is required for light-dependent Rhodopsin-1 clearance and photoreceptor survival

por Huang, Huai-Wei, Ryoo, Hyung Don
Publicado 2021

Drosophila IAP antagonists form multimeric complexes to promote cell death

por Sandu, Cristinel, Ryoo, Hyung Don, Steller, Hermann
Publicado 2010

Cdk5 and Mekk1 mediate a Pro-Apoptotic Signaling Response to Endoplasmic Reticulum Stress in a Drosophila Model of Autosomal Dominant Retinitis Pigmentosa

por Kang, Min-Ji, Chung, Jaehoon, Ryoo, Hyung Don
Publicado 2012

Drosophila XBP1 Expression Reporter Marks Cells under Endoplasmic Reticulum Stress and with High Protein Secretory Load

por Ryoo, Hyung Don, Li, Josepher, Kang, Min-Ji
Publicado 2013

Integration of UPR(ER) and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation

por Wang, Lifen, Zeng, Xiankun, Ryoo, Hyung Don, Jasper, Heinrich
Publicado 2014

PERK Limits Drosophila Lifespan by Promoting Intestinal Stem Cell Proliferation in Response to ER Stress

por Wang, Lifen, Ryoo, Hyung Don, Qi, Yanyan, Jasper, Heinrich
Publicado 2015

The requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development

por Huang, Huai-Wei, Zeng, Xiaomei, Rhim, Taiyoun, Ron, David, Ryoo, Hyung Don
Publicado 2017

The transcription factor Xrp1 is required for PERK-mediated antioxidant gene induction in Drosophila

por Brown, Brian, Mitra, Sahana, Roach, Finnegan D, Vasudevan, Deepika, Ryoo, Hyung Don
Publicado 2021

A protein-trap allele reveals roles for Drosophila ATF4 in photoreceptor degeneration, oogenesis and wing development

por Vasudevan, Deepika, Katow, Hidetaka, Huang, Huai-Wei, Tang, Grace, Ryoo, Hyung Don
Publicado 2022

Regulation of the Drosophila Apoptosome through Feedback Inhibition

por Shapiro, Peter J., Hsu, Hans H., Jung, Heekyung, Robbins, Edith S., Ryoo, Hyung Don
Publicado 2008

highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models

por Huang, Huai-Wei, Brown, Brian, Chung, Jaehoon, Domingos, Pedro M., Ryoo, Hyung Don
Publicado 2018

A Drosophila Reporter for the Translational Activation of ATF4 Marks Stressed Cells during Development

por Kang, Kwonyoon, Ryoo, Hyung Don, Park, Jung-Eun, Yoon, Jee-Hyun, Kang, Min-Ji
Publicado 2015

Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster

por Tien, An-Chi, Rajan, Akhila, Schulze, Karen L., Ryoo, Hyung Don, Acar, Melih, Steller, Hermann, Bellen, Hugo J.
Publicado 2008

Translational induction of ATF4 during integrated stress response requires noncanonical initiation factors eIF2D and DENR

por Vasudevan, Deepika, Neuman, Sarah D., Yang, Amy, Lough, Lea, Brown, Brian, Bashirullah, Arash, Cardozo, Timothy, Ryoo, Hyung Don
Publicado 2020

Role of Drosophila EDEMs in the degradation of the alpha-1-antitrypsin Z variant

por JANG, BO-YUN, RYOO, HYUNG DON, SON, JAEKYOUNG, CHOI, KYUNG-CHUL, SHIN, DONG-MYOUNG, KANG, SANG-WOOK, KANG, MIN-JI
Publicado 2015

Triazolo[4,5-d]pyrimidines as Validated General Control Nonderepressible 2 (GCN2) Protein Kinase Inhibitors Reduce Growth of Leukemia Cells

por Lough, Lea, Sherman, Dan, Becerra-Flores, Manuel, Vasudevan, Deepika, Lavinda, Olga, Ni, Eric, Wang, Hong, Ryoo, Hyung Don, Tibes, Raoul, Cardozo, Timothy
Publicado 2018

Hyperactivated Wnt Signaling Induces Synthetic Lethal Interaction with Rb Inactivation by Elevating TORC1 Activities

por Zhang, Tianyi, Liao, Yang, Hsu, Fu-Ning, Zhang, Robin, Searle, Jennifer S., Pei, Xun, Li, Xuan, Ryoo, Hyung Don, Ji, Jun-Yuan, Du, Wei
Publicado 2014

4E-BP is a target of the GCN2–ATF4 pathway during Drosophila development and aging

por Kang, Min-Ji, Vasudevan, Deepika, Kang, Kwonyoon, Kim, Kyunggon, Park, Jung-Eun, Zhang, Nan, Zeng, Xiaomei, Neubert, Thomas A., Marr, Michael T., Ryoo, Hyung Don
Publicado 2017