Biochemical and biophysical characterization of the main protease, 3-chymotrypsin-like protease (3CLpro) from the novel coronavirus SARS-CoV 2

por Ferreira, Juliana C., Rabeh, Wael M.
Publicado 2020

Key dimer interface residues impact the catalytic activity of 3CLpro, the main protease of SARS-CoV-2

por Ferreira, Juliana C., Fadl, Samar, Rabeh, Wael M.
Publicado 2022

Hexokinase II–derived cell-penetrating peptide targets mitochondria and triggers apoptosis in cancer cells

por Woldetsadik, Abiy D., Vogel, Maria C., Rabeh, Wael M., Magzoub, Mazin
Publicado 2017

Catalytic Dyad Residues His41 and Cys145 Impact the Catalytic Activity and Overall Conformational Fold of the Main SARS-CoV-2 Protease 3-Chymotrypsin-Like Protease

por Ferreira, Juliana C., Fadl, Samar, Villanueva, Adrian J., Rabeh, Wael M.
Publicado 2021

pH profiles of 3-chymotrypsin-like protease (3CLpro) from SARS-CoV-2 elucidate its catalytic mechanism and a histidine residue critical for activity

por Al Adem, Kenana, Ferreira, Juliana C., Fadl, Samar, Rabeh, Wael M.
Publicado 2022

Regulation and Cytoprotective Role of Hexokinase III

por Wyatt, Eugene, Wu, Rongxue, Rabeh, Wael, Park, Hee-Won, Ghanefar, Mohsen, Ardehali, Hossein
Publicado 2010

Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS‐CoV‐2 protease 3CLpro

por Ferreira, Juliana C., Fadl, Samar, Ilter, Metehan, Pekel, Hanife, Rezgui, Rachid, Sensoy, Ozge, Rabeh, Wael M.
Publicado 2021

The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation

por Nawaz, Mir Hussain, Ferreira, Juliana C., Nedyalkova, Lyudmila, Zhu, Haizhong, Carrasco-López, César, Kirmizialtin, Serdal, Rabeh, Wael M.
Publicado 2018

Linker residues regulate the activity and stability of hexokinase 2, a promising anticancer target

por Ferreira, Juliana C., Khrbtli, Abdul-Rahman, Shetler, Cameron L., Mansoor, Samman, Ali, Liaqat, Sensoy, Ozge, Rabeh, Wael M.
Publicado 2020

Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier–dependent pathway

por Ahner, Annette, Gong, Xiaoyan, Schmidt, Bela Z., Peters, Kathryn W., Rabeh, Wael M., Thibodeau, Patrick H., Lukacs, Gergely L., Frizzell, Raymond A.
Publicado 2013

Beetle luciferases with naturally red- and blue-shifted emission

por Carrasco-López, César, Ferreira, Juliana C, Lui, Nathan M, Schramm, Stefan, Berraud-Pache, Romain, Navizet, Isabelle, Panjikar, Santosh, Naumov, Panče, Rabeh, Wael M
Publicado 2018

The Discovery of Small Allosteric and Active Site Inhibitors of the SARS-CoV-2 Main Protease via Structure-Based Virtual Screening and Biological Evaluation

por Mahgoub, Radwa E., Mohamed, Feda E., Alzyoud, Lara, Ali, Bassam R., Ferreira, Juliana, Rabeh, Wael M., AlNeyadi, Shaikha S., Atatreh, Noor, Ghattas, Mohammad A.
Publicado 2022

Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+)

por Tempel, Wolfram, Rabeh, Wael M, Bogan, Katrina L, Belenky, Peter, Wojcik, Marzena, Seidle, Heather F, Nedyalkova, Lyudmila, Yang, Tianle, Sauve, Anthony A, Park, Hee-Won, Brenner, Charles
Publicado 2007

Crystallographic education in the 21st century

por Gražulis, Saulius, Sarjeant, Amy Alexis, Moeck, Peter, Stone-Sundberg, Jennifer, Snyder, Trevor J., Kaminsky, Werner, Oliver, Allen G., Stern, Charlotte L., Dawe, Louise N., Rychkov, Denis A., Losev, Evgeniy A., Boldyreva, Elena V., Tanski, Joseph M., Bernstein, Joel, Rabeh, Wael M., Kantardjieff, Katherine A.
Publicado 2015