The effect of normalisation and error model choice on the distribution of the maximum likelihood estimator for a biochemical reaction

por Thomaseth, Caterina, Radde, Nicole E.
Publicado 2022

Sampling-based Bayesian approaches reveal the importance of quasi-bistable behavior in cellular decision processes on the example of the MAPK signaling pathway in PC-12 cell lines

por Jensch, Antje, Thomaseth, Caterina, Radde, Nicole E.
Publicado 2017

Bayesian estimation reveals that reproducible models in Systems Biology get more citations

por Höpfl, Sebastian, Pleiss, Jürgen, Radde, Nicole E.
Publicado 2023

On the accuracy of the epigenetic copy machine: comprehensive specificity analysis of the DNMT1 DNA methyltransferase

por Adam, Sabrina, Klingel, Viviane, Radde, Nicole E, Bashtrykov, Pavel, Jeltsch, Albert
Publicado 2023

Model-Based Design of a Synthetic Oscillator Based on an Epigenetic Methylation Memory System

por Klingel, Viviane, Graf, Dimitri, Weirich, Sara, Jeltsch, Albert, Radde, Nicole E.
Publicado 2022

A computational model of PKD and CERT interactions at the trans-Golgi network of mammalian cells

por Weber, Patrick, Hornjik, Mariana, Olayioye, Monilola A, Hausser, Angelika, Radde, Nicole E
Publicado 2015

Impact of measurement noise, experimental design, and estimation methods on Modular Response Analysis based network reconstruction

por Thomaseth, Caterina, Fey, Dirk, Santra, Tapesh, Rukhlenko, Oleksii S., Radde, Nicole E., Kholodenko, Boris N.
Publicado 2018

MEMO: multi-experiment mixture model analysis of censored data

por Geissen, Eva-Maria, Hasenauer, Jan, Heinrich, Stephanie, Hauf, Silke, Theis, Fabian J., Radde, Nicole E.
Publicado 2016

Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns

por Adam, Sabrina, Bräcker, Julia, Klingel, Viviane, Osteresch, Bernd, Radde, Nicole E., Brockmeyer, Jens, Bashtrykov, Pavel, Jeltsch, Albert
Publicado 2022

DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

por Adam, Sabrina, Anteneh, Hiwot, Hornisch, Maximilian, Wagner, Vincent, Lu, Jiuwei, Radde, Nicole E., Bashtrykov, Pavel, Song, Jikui, Jeltsch, Albert
Publicado 2020