Dynamic template-assisted strategies in fragment-based drug discovery

por Schmidt, Marco F., Rademann, Jörg
Publicado 2009

Protein‐Templated Formation of an Inhibitor of the Blood Coagulation Factor Xa through a Background‐Free Amidation Reaction

por Jaegle, Mike, Steinmetzer, Torsten, Rademann, Jörg
Publicado 2017

Corrigendum to: Off‐target inhibition by active site‐targeting SHP2 inhibitors

por Tsutsumi, Ryouhei, Ran, Hao, Rademann, Jörg, Neel, Benjamin G.
Publicado 2019

Mapping Protein–Protein Interactions of the Resistance-Related Bacterial Zeta Toxin–Epsilon Antitoxin Complex (ε(2)ζ(2)) with High Affinity Peptide Ligands Using Fluorescence Polar...

por Fernández-Bachiller, María Isabel, Brzozowska, Iwona, Odolczyk, Norbert, Zielenkiewicz, Urszula, Zielenkiewicz, Piotr, Rademann, Jörg
Publicado 2016

High yield expression of catalytically active USP18 (UBP43) using a Trigger Factor fusion system

por Basters, Anja, Ketscher, Lars, Deuerling, Elke, Arkona, Christoph, Rademann, Jörg, Knobeloch, Klaus-Peter, Fritz, Günter
Publicado 2012

Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease

por Zhu, Lili, George, Shyla, Schmidt, Marco F., Al-Gharabli, Samer I., Rademann, Jörg, Hilgenfeld, Rolf
Publicado 2011

Irreversible inhibitors of the 3C protease of Coxsackie virus through templated assembly of protein-binding fragments

por Becker, Daniel, Kaczmarska, Zuzanna, Arkona, Christoph, Schulz, Robert, Tauber, Carolin, Wolber, Gerhard, Hilgenfeld, Rolf, Coll, Miquel, Rademann, Jörg
Publicado 2016

Design of chemical libraries with potentially bioactive molecules applying a maximum common substructure concept

por Lisurek, Michael, Rupp, Bernd, Wichard, Jörg, Neuenschwander, Martin, von Kries, Jens Peter, Frank, Ronald, Rademann, Jörg, Kühne, Ronald
Publicado 2009

Biological Characterization, Mechanistic Investigation and Structure‐Activity Relationships of Chemically Stable TLR2 Antagonists

por Bermudez, Marcel, Grabowski, Maria, Murgueitio, Manuela S., Tiemann, Markus, Varga, Péter, Rudolf, Thomas, Wolber, Gerhard, Weindl, Günther, Rademann, Jörg
Publicado 2020

A Formylglycine‐Peptide for the Site‐Directed Identification of Phosphotyrosine‐Mimetic Fragments

por Tiemann, Markus, Nawrotzky, Eric, Schmieder, Peter, Wehrhan, Leon, Bergemann, Silke, Martos, Vera, Song, Wei, Arkona, Christoph, Keller, Bettina G., Rademann, Jörg
Publicado 2022

The transcription factor STAT5 catalyzes Mannich ligation reactions yielding inhibitors of leukemic cell proliferation

por Wong, Ee Lin, Nawrotzky, Eric, Arkona, Christoph, Kim, Boo Geun, Beligny, Samuel, Wang, Xinning, Wagner, Stefan, Lisurek, Michael, Carstanjen, Dirk, Rademann, Jörg
Publicado 2019

IR action spectroscopy of glycosaminoglycan oligosaccharides

por Lettow, Maike, Grabarics, Márkó, Mucha, Eike, Thomas, Daniel A., Polewski, Łukasz, Freyse, Joanna, Rademann, Jörg, Meijer, Gerard, von Helden, Gert, Pagel, Kevin
Publicado 2019

Pentafluorophosphato‐Phenylalanines: Amphiphilic Phosphotyrosine Mimetics Displaying Fluorine‐Specific Protein Interactions

por Accorsi, Matteo, Tiemann, Markus, Wehrhan, Leon, Finn, Lauren M., Cruz, Ruben, Rautenberg, Max, Emmerling, Franziska, Heberle, Joachim, Keller, Bettina G., Rademann, Jörg
Publicado 2022

Incorporation of Amino Acids with Long-Chain Terminal Olefins into Proteins

por Exner, Matthias P., Köhling, Sebastian, Rivollier, Julie, Gosling, Sandrine, Srivastava, Puneet, Palyancheva, Zheni I., Herdewijn, Piet, Heck, Marie-Pierre, Rademann, Jörg, Budisa, Nediljko
Publicado 2016

Peptide–polymer ligands for a tandem WW-domain, an adaptive multivalent protein–protein interaction: lessons on the thermodynamic fitness of flexible ligands

por Koschek, Katharina, Durmaz, Vedat, Krylova, Oxana, Wieczorek, Marek, Gupta, Shilpi, Richter, Martin, Bujotzek, Alexander, Fischer, Christina, Haag, Rainer, Freund, Christian, Weber, Marcus, Rademann, Jörg
Publicado 2015

Chemical Evolution of Antivirals Against Enterovirus D68 through Protein‐Templated Knoevenagel Reactions

por Tauber, Carolin, Wamser, Rebekka, Arkona, Christoph, Tügend, Marisa, Abdul Aziz, Umer Bin, Pach, Szymon, Schulz, Robert, Jochmans, Dirk, Wolber, Gerhard, Neyts, Johan, Rademann, Jörg
Publicado 2021

Sulfated Hyaluronan Derivatives Modulate TGF-β1:Receptor Complex Formation: Possible Consequences for TGF-β1 Signaling

por Koehler, Linda, Samsonov, Sergey, Rother, Sandra, Vogel, Sarah, Köhling, Sebastian, Moeller, Stephanie, Schnabelrauch, Matthias, Rademann, Jörg, Hempel, Ute, Pisabarro, M. Teresa, Scharnweber, Dieter, Hintze, Vera
Publicado 2017

Syntheses of defined sulfated oligohyaluronans reveal structural effects, diversity and thermodynamics of GAG–protein binding

por Köhling, Sebastian, Blaszkiewicz, Joanna, Ruiz-Gómez, Gloria, Fernández-Bachiller, María Isabel, Lemmnitzer, Katharina, Panitz, Nydia, Beck-Sickinger, Annette G., Schiller, Jürgen, Pisabarro, M. Teresa, Rademann, Jörg
Publicado 2018

Dual Action of Sulfated Hyaluronan on Angiogenic Processes in Relation to Vascular Endothelial Growth Factor-A

por Koehler, Linda, Ruiz-Gómez, Gloria, Balamurugan, Kanagasabai, Rother, Sandra, Freyse, Joanna, Möller, Stephanie, Schnabelrauch, Matthias, Köhling, Sebastian, Djordjevic, Snezana, Scharnweber, Dieter, Rademann, Jörg, Pisabarro, M. Teresa, Hintze, Vera
Publicado 2019

Sulfated glycosaminoglycans inhibit transglutaminase 2 by stabilizing its closed conformation

por Müller, Claudia Damaris, Ruiz-Gómez, Gloria, Cazzonelli, Sophie, Möller, Stephanie, Wodtke, Robert, Löser, Reik, Freyse, Joanna, Dürig, Jan-Niklas, Rademann, Jörg, Hempel, Ute, Pisabarro, M. Teresa, Vogel, Sarah
Publicado 2022