Host-specific functional compartmentalization within the oligopeptide transporter during the Borrelia burgdorferi enzootic cycle

por Groshong, Ashley M., McLain, Melissa A., Radolf, Justin D.
Publicado 2021

Borrelia burgdorferi Requires the Alternative Sigma Factor RpoS for Dissemination within the Vector during Tick-to-Mammal Transmission

por Dunham-Ems, Star M., Caimano, Melissa J., Eggers, Christian H., Radolf, Justin D.
Publicado 2012

Peptide Uptake Is Essential for Borrelia burgdorferi Viability and Involves Structural and Regulatory Complexity of its Oligopeptide Transporter

por Groshong, Ashley M., Dey, Abhishek, Bezsonova, Irina, Caimano, Melissa J., Radolf, Justin D.
Publicado 2017

HrpA, an RNA Helicase Involved in RNA Processing, Is Required for Mouse Infectivity and Tick Transmission of the Lyme Disease Spirochete

por Salman-Dilgimen, Aydan, Hardy, Pierre-Olivier, Radolf, Justin D., Caimano, Melissa J., Chaconas, George
Publicado 2013

Borrelia burgdorferi Requires Glycerol for Maximum Fitness During The Tick Phase of the Enzootic Cycle

por Pappas, Christopher J., Iyer, Radha, Petzke, Mary M., Caimano, Melissa J., Radolf, Justin D., Schwartz, Ira
Publicado 2011

The major outer sheath protein forms distinct conformers and multimeric complexes in the outer membrane and periplasm of Treponema denticola

por Puthenveetil, Robbins, Kumar, Sanjiv, Caimano, Melissa J., Dey, Abhishek, Anand, Arvind, Vinogradova, Olga, Radolf, Justin D.
Publicado 2017

CD14 Signaling Restrains Chronic Inflammation through Induction of p38-MAPK/SOCS-Dependent Tolerance

por Sahay, Bikash, Patsey, Rebeca L., Eggers, Christian H., Salazar, Juan C., Radolf, Justin D., Sellati, Timothy J.
Publicado 2009

Two Distinct Mechanisms Govern RpoS-Mediated Repression of Tick-Phase Genes during Mammalian Host Adaptation by Borrelia burgdorferi, the Lyme Disease Spirochete

por Grove, Arianna P., Liveris, Dionysios, Iyer, Radha, Petzke, Mary, Rudman, Joseph, Caimano, Melissa J., Radolf, Justin D., Schwartz, Ira
Publicado 2017

MyD88 Deficiency Markedly Worsens Tissue Inflammation and Bacterial Clearance in Mice Infected with Treponema pallidum, the Agent of Syphilis

por Silver, Adam C., Dunne, Dana W., Zeiss, Caroline J., Bockenstedt, Linda K., Radolf, Justin D., Salazar, Juan C., Fikrig, Erol
Publicado 2013

BosR and PlzA reciprocally regulate RpoS function to sustain Borrelia burgdorferi in ticks and mammals

por Grassmann, André A., Tokarz, Rafal, Golino, Caroline, McLain, Melissa A., Groshong, Ashley M., Radolf, Justin D., Caimano, Melissa J.
Publicado 2023

The Tprk Protein of Treponema pallidum Is Periplasmic and Is Not a Target of Opsonic Antibody or Protective Immunity

por Hazlett, Karsten R.O., Sellati, Timothy J., Nguyen, Tung T., Cox, David L., Clawson, Michael L., Caimano, Melissa J., Radolf, Justin D.
Publicado 2001

Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes

por Kenedy, Melisha R., Scott, Edgar J., Shrestha, Binu, Anand, Arvind, Iqbal, Henna, Radolf, Justin D., Dyer, David W., Akins, Darrin R.
Publicado 2016

PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi

por Groshong, Ashley M., Grassmann, André A., Luthra, Amit, McLain, Melissa A., Provatas, Anthony A., Radolf, Justin D., Caimano, Melissa J.
Publicado 2021

Role of Acetyl-Phosphate in Activation of the Rrp2-RpoN-RpoS Pathway in Borrelia burgdorferi

por Xu, Haijun, Caimano, Melissa J., Lin, Tao, He, Ming, Radolf, Justin D., Norris, Steven J., Gheradini, Frank, Wolfe, Alan J., Yang, X. Frank
Publicado 2010

Correction: Role of Acetyl-Phosphate in Activation of the Rrp2-RpoN-RpoS Pathway in Borrelia burgdorferi

por Xu, Haijun, Caimano, Melissa J., Lin, Tao, He, Ming, Radolf, Justin D., Norris, Steven J., Gherardini, Frank, Wolfe, Alan J., Yang, X. Frank
Publicado 2010

Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine

por Hawley, Kelly L., Montezuma-Rusca, Jairo M., Delgado, Kristina N., Singh, Navreeta, Uversky, Vladimir N., Caimano, Melissa J., Radolf, Justin D., Luthra, Amit
Publicado 2021

Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

por Benjamin, Sarah J., Hawley, Kelly L., Vera-Licona, Paola, La Vake, Carson J., Cervantes, Jorge L., Ruan, Yijun, Radolf, Justin D., Salazar, Juan C.
Publicado 2021

Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β

por Salazar, Juan C., Duhnam-Ems, Star, La Vake, Carson, Cruz, Adriana R., Moore, Meagan W., Caimano, Melissa J., Velez-Climent, Leonor, Shupe, Jonathan, Krueger, Winfried, Radolf, Justin D.
Publicado 2009

A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the ser...

por Seña, Arlene C., Zhang, Xiao-Hui, Li, Trudy, Zheng, He-Ping, Yang, Bin, Yang, Li-Gang, Salazar, Juan C., Cohen, Myron S., Moody, M. Anthony, Radolf, Justin D., Tucker, Joseph D.
Publicado 2015

The RpoS Gatekeeper in Borrelia burgdorferi: An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity

por Caimano, Melissa J., Groshong, Ashley M., Belperron, Alexia, Mao, Jialing, Hawley, Kelly L., Luthra, Amit, Graham, Danielle E., Earnhart, Christopher G., Marconi, Richard T., Bockenstedt, Linda K., Blevins, Jon S., Radolf, Justin D.
Publicado 2019