Integration of Immunome With Disease-Gene Network Reveals Common Cellular Mechanisms Between IMIDs and Drug Repurposing Strategies

por Devaprasad, Abhinandan, Radstake, Timothy R. D. J., Pandit, Aridaman
Publicado 2021

RegEnrich gene regulator enrichment analysis reveals a key role of the ETS transcription factor family in interferon signaling

por Tao, Weiyang, Radstake, Timothy R. D. J., Pandit, Aridaman
Publicado 2022

Update on biomarkers in systemic sclerosis: tools for diagnosis and treatment

por Affandi, Alsya J., Radstake, Timothy R. D. J., Marut, Wioleta
Publicado 2015

Genetics of Systemic Sclerosis: An Update

por Broen, Jasper C. A., Coenen, Marieke J. H., Radstake, Timothy R. D. J.
Publicado 2011

Unmet Needs in Systemic Sclerosis Understanding and Treatment: the Knowledge Gaps from a Scientist’s, Clinician’s, and Patient’s Perspective

por Cossu, Marta, Beretta, Lorenzo, Mosterman, Petra, de Hair, Maria J. H., Radstake, Timothy R. D. J.
Publicado 2017

Fc Gamma Receptor IIb on GM-CSF Macrophages Controls Immune Complex Mediated Inhibition of Inflammatory Signals

por Santegoets, Kim C. M., Wenink, Mark H., van den Berg, Wim B., Radstake, Timothy R. D. J.
Publicado 2014

First-line csDMARD monotherapy drug retention in psoriatic arthritis: methotrexate outperforms sulfasalazine

por Jacobs, Marleen E, Pouw, Juliëtte N, Welsing, Paco, Radstake, Timothy R D J, Leijten, Emmerik F A
Publicado 2020

CXCL4 suppresses tolerogenic immune signature of monocyte‐derived dendritic cells

por Silva‐Cardoso, Sandra C., Tao, Weiyang, Fernández, Beatriz Malvar, Boes, Marianne, Radstake, Timothy R.D.J., Pandit, Aridaman
Publicado 2020

Leukocyte Associated Immunoglobulin Like Receptor 1 Regulation and Function on Monocytes and Dendritic Cells During Inflammation

por Carvalheiro, Tiago, Garcia, Samuel, Pascoal Ramos, M. Inês, Giovannone, Barbara, Radstake, Timothy R. D. J., Marut, Wioleta, Meyaard, Linde
Publicado 2020

Morphea and Eosinophilic Fasciitis: An Update

por Mertens, Jorre S., Seyger, Marieke M. B., Thurlings, Rogier M., Radstake, Timothy R. D. J., de Jong, Elke M. G. J.
Publicado 2017

DNAM1 and TIGIT balance the T cell response, with low T cell TIGIT expression corresponding to inflammation in psoriatic disease

por Jacobs, Marleen E, Pouw, Juliëtte N, Olde Nordkamp, Michel A, Radstake, Timothy R D J, Leijten, Emmerik F A, Boes, Marianne
Publicado 2020

Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner

por Carvalheiro, Tiago, Rafael-Vidal, Carlos, Malvar-Fernandez, Beatriz, Lopes, Ana P., Pego-Reigosa, Jose M., Radstake, Timothy R. D. J., Garcia, Samuel
Publicado 2020

Multiomics and Machine Learning Accurately Predict Clinical Response to Adalimumab and Etanercept Therapy in Patients With Rheumatoid Arthritis

por Tao, Weiyang, Concepcion, Arno N., Vianen, Marieke, Marijnissen, Anne C. A., Lafeber, Floris P. G. J., Radstake, Timothy R. D. J., Pandit, Aridaman
Publicado 2020

Activation-induced colocalisation of SCAMP5 with IFNα in human plasmacytoid dendritic cells

por Pouw, Juliëtte N, Olde Nordkamp, Michel A M, O'Toole, Tom G, Radstake, Timothy R D J, Leijten, Emmerik F A, Boes, Marianne
Publicado 2022

Decreased circulating CXCR3 + CCR9+T helper cells are associated with elevated levels of their ligands CXCL10 and CCL25 in the salivary gland of patients with Sjögren’s syndrome to...

por Blokland, Sofie L. M., Kislat, Andreas, Homey, Bernhard, Smithson, Glennda M., Kruize, Aike A., Radstake, Timothy R. D. J., van Roon, Joel A. G.
Publicado 2019

Characterization of Long Non-Coding RNAs in Systemic Sclerosis Monocytes: A Potential Role for PSMB8-AS1 in Altered Cytokine Secretion

por Servaas, Nila H., Mariotti, Barbara, van der Kroef, Maarten, Wichers, Catharina G. K., Pandit, Aridaman, Bazzoni, Flavia, Radstake, Timothy R. D. J., Rossato, Marzia
Publicado 2021

The Pronounced Th17 Profile in Systemic Sclerosis (SSc) Together with Intracellular Expression of TGFβ and IFNγ Distinguishes SSc Phenotypes

por Radstake, Timothy R. D. J., van Bon, Lenny, Broen, Jasper, Hussiani, Anila, Hesselstrand, Roger, Wuttge, Dirk M., Deng, Yanhui, Simms, Robbert, Lubberts, Erik, Lafyatis, Robert
Publicado 2009

Increased Frequency and Compromised Function of T Regulatory Cells in Systemic Sclerosis (SSc) Is Related to a Diminished CD69 and TGFβ Expression

por Radstake, Timothy R. D. J., van Bon, Lenny, Broen, Jasper, Wenink, Mark, Santegoets, Kim, Deng, Yanhui, Hussaini, Anila, Simms, Robert, Cruikshank, William W., Lafyatis, Robert
Publicado 2009

Soluble Immune Complexes Shift the TLR-Induced Cytokine Production of Distinct Polarized Human Macrophage Subsets towards IL-10

por Ambarus, Carmen A., Santegoets, Kim C. M., van Bon, Lenny, Wenink, Mark H., Tak, Paul P., Radstake, Timothy R. D. J., Baeten, Dominique L. P.
Publicado 2012

Differential isoform expression of Allergin‐1 during acute and chronic inflammation

por Geerdink, Ruben J., Pascoal Ramos, Maria Inês, van den Hoogen, Luuk L., Radstake, Timothy R. D. J., Shibayama, Shiro, Shibuya, Akira, Bont, Louis, Meyaard, Linde
Publicado 2022