PD-1 and BTLA and CD8(+) T-cell “exhaustion” in cancer: “Exercising” an alternative viewpoint

por Haymaker, Cara, Wu, Richard, Bernatchez, Chantale, Radvanyi, Laszlo
Publicado 2012

New insights on the role of CD8(+)CD57(+) T-cells in cancer

por Wu, Richard C., Hwu, Patrick, Radvanyi, Laszlo G.
Publicado 2012

Current State of Immunotherapy and Mechanisms of Immune Evasion in Ewing Sarcoma and Osteosarcoma

por Evdokimova, Valentina, Gassmann, Hendrik, Radvanyi, Laszlo, Burdach, Stefan E. G.
Publicado 2022

Immediate triggering of 4-1BB co-stimulation during initiation of tumor-infiltrating lymphocyte (TIL) expansion from melanoma tumors accelerates CD8+ T-cell outgrowth and tumor spe...

por Chacon, Jessica, Pilon-Thomas, Shari, Sarnaik, Amod, Hwu, Patrick, Radvanyi, Laszlo
Publicado 2013

Continuous 4–1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy

por Chacon, Jessica Ann, Pilon-Thomas, Shari, Sarnaik, Amod A, Radvanyi, Laszlo G
Publicado 2013

Defective STAT1 activation associated with impaired IFN-γ production in NK and T lymphocytes from metastatic melanoma patients treated with IL-2

por Sim, Geok Choo, Wu, Sheng, Jin, Lei, Hwu, Patrick, Radvanyi, Laszlo G.
Publicado 2016

IL-2 analogues: novel agents circumventing the expansion of T regulatory cells while promoting NK cell activation during IL-2 therapy

por Sim, Geok Choo, Grimm, Elizabeth, Dai, ZhiMin, Overwijk, Willem, Hwu, Patrick, Radvanyi, Laszlo
Publicado 2013

Single-cell motility and gene expression signature as predictors of the overall survival of act in melanoma patients

por Martinez-Paniagua, Melisa, Haymaker, Cara, Adolacion, Jay R, Radvanyi, Laszlo, Hwu, Patrick, Roysam, Badrinath, Bernatchez, Chantale, Varadarajan, Navin
Publicado 2015

COVID‐19: a pandemic experience that illuminates potential reforms to health research

por Kozlowski, Hannah N, Farkouh, Michael E, Irwin, Meredith S, Radvanyi, Laszlo G, Schimmer, Aaron D, Tabori, Uri, Rosenblum, Norman D
Publicado 2020

A new approach for the large-scale generation of mature dendritic cells from adherent PBMC using roller bottle technology

por Campbell-Anson, Ryan E, Kentor, Diane, Wang, Yi J, Bushnell, Kathryn M, Li, Yufeng, Vence, Luis M, Radvanyi, Laszlo G
Publicado 2008

Development of novel combinations of targeted and immunotherapies by understanding immune resistance using a high throughput assay of T cell mediated cytotoxicity

por Malu, Shruti, Mbofung, Rina, Khalili, Jahan, Satani, Nikunj, Forget, Marie-Andrée, Haymaker, Cara, Muller, Florian, Bernatchez, Chantale, Radvanyi, Laszlo, Hwu, Patrick
Publicado 2013

Co-Stimulation through 4-1BB/CD137 Improves the Expansion and Function of CD8(+) Melanoma Tumor-Infiltrating Lymphocytes for Adoptive T-Cell Therapy

por Chacon, Jessica Ann, Wu, Richard C., Sukhumalchandra, Pariya, Molldrem, Jeffrey J., Sarnaik, Amod, Pilon-Thomas, Shari, Weber, Jeffrey, Hwu, Patrick, Radvanyi, Laszlo
Publicado 2013

VISTA expression and patient selection for immune-based anticancer therapy

por Martin, Alexander S., Molloy, Michael, Ugolkov, Andrey, von Roemeling, Reinhard W., Noelle, Randolph J., Lewis, Lionel D., Johnson, Melissa, Radvanyi, Laszlo, Martell, Robert E.
Publicado 2023

Identification of predictive biomarker signatures in melanoma tumors associated with response to tumor-infiltrating lymphocyte (TIL) therapy

por Chen, Jie Qing, Creasy, Caitlin, Cabala, Carlos Antonio Torres, Ekmekcioglu, Suhendan, Maiti, Sourindra N, Roszik, Jason, Haymaker, Cara, Bernatchez, Chantale, Hwu, Patrick, Radvanyi, Laszlo
Publicado 2013

Uncovering a novel function of BTLA on tumor-infiltrating CD8+ T cells

por Haymaker, Cara, Wu, Richard, Ritthipichai, Krit, Bernatchez, Chantale, Forget, Marie-Andree, Chen, Jie Qing, Liu, Hiu, Wang, Ena, Marincola, Francesco, Hwu, Patrick, Radvanyi, Laszlo
Publicado 2013

Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells

por An, Xingyue, Sendra, Victor G., Liadi, Ivan, Ramesh, Balakrishnan, Romain, Gabrielle, Haymaker, Cara, Martinez-Paniagua, Melisa, Lu, Yanbin, Radvanyi, Laszlo G., Roysam, Badrinath, Varadarajan, Navin
Publicado 2017

The beneficial effects of a gas-permeable flask for expansion of Tumor-Infiltrating lymphocytes as reflected in their mitochondrial function and respiration capacity

por Forget, Marie-Andrée, Haymaker, Cara, Dennison, Jennifer B, Toth, Christopher, Maiti, Sourindra, Fulbright, Orenthial J, Cooper, Laurence J N, Hwu, Patrick, Radvanyi, Laszlo G, Bernatchez, Chantale
Publicado 2015

Genetically modified artificial antigen-presenting cells (aAPC) for expansion of melanoma tumor infiltrating lymphocytes with optimal properties for adoptive cell therapy

por Forget, Marie-Andrée, Malu, Shruti, Liu, Hiu, Toth, Christopher, Maiti, Sourindra, Kale, Charuta, Bernatchez, Chantale, Huls, Helen, Wang, Ena, Hwu, Patrick, Cooper, Laurence J, Radvanyi, Laszlo G
Publicado 2013

BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties

por Haymaker, Cara L, Wu, Richard C, Ritthipichai, Krit, Bernatchez, Chantale, Forget, Marie-Andrée, Chen, Jie Qing, Liu, Hui, Wang, Ena, Marincola, Francesco, Hwu, Patrick, Radvanyi, Laszlo G
Publicado 2015

Analysis of the Intratumoral Adaptive Immune Response in Well Differentiated and Dedifferentiated Retroperitoneal Liposarcoma

por Tseng, William W., Malu, Shruti, Zhang, Minying, Chen, Jieqing, Sim, Geok Choo, Wei, Wei, Ingram, Davis, Somaiah, Neeta, Lev, Dina C., Pollock, Raphael E., Lizée, Gregory, Radvanyi, Laszlo, Hwu, Patrick
Publicado 2015