Targeting the BRCA1/2 deficient cancer with PARP inhibitors: Clinical outcomes and mechanistic insights

por Ragupathi, Ashwin, Singh, Manrose, Perez, Alexis M., Zhang, Dong
Publicado 2023

Site-Specific Tryptophan Labels Reveal Local Microsecond–Millisecond Motions of Dihydrofolate Reductase

por Vaughn, Morgan B., Biren, Chloe, Li, Qun, Ragupathi, Ashwin, Dyer, R. Brian
Publicado 2020

Temporal Modulation of HER2 Membrane Availability Increases Pertuzumab Uptake and Pretargeted Molecular Imaging of Gastric Tumors

por Pereira, Patrícia M.R., Mandleywala, Komal, Ragupathi, Ashwin, Carter, Lukas M., Goos, Jeroen A.C.M., Janjigian, Yelena Y., Lewis, Jason S.
Publicado 2019

Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy

por Pereira, Patrícia M. R., Sharma, Sai Kiran, Carter, Lukas M., Edwards, Kimberly J., Pourat, Jacob, Ragupathi, Ashwin, Janjigian, Yelena Y., Durack, Jeremy C., Lewis, Jason S.
Publicado 2018

Caveolin-1 temporal modulation enhances antibody drug efficacy in heterogeneous gastric cancer

por Pereira, Patrícia M. R., Mandleywala, Komal, Monette, Sébastien, Lumish, Melissa, Tully, Kathryn M., Panikar, Sandeep Surendra, Cornejo, Mike, Mauguen, Audrey, Ragupathi, Ashwin, Keltee, Nai C., Mattar, Marissa, Janjigian, Yelena Y., Lewis, Jason S.
Publicado 2022

Synthesis and Comparative In Vivo Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET

por Sharma, Sai Kiran, Adumeau, Pierre, Keinänen, Outi, Sisodiya, Vikram, Sarvaiya, Hetal, Tchelepi, Robert, Korsen, Joshua A, Pourat, Jacob, Edwards, Kimberly J., Ragupathi, Ashwin, Hamdy, Omar, Saunders, Laura R., Rudin, Charles M., Poirier, John T., Lewis, Jason S., Zeglis, Brian M.
Publicado 2021