Demystifying extrachromosomal DNA circles: Categories, biogenesis, and cancer therapeutics

por Wu, Manrong, Rai, Kunal
Publicado 2022

Dnmt3 and G9a Cooperate for Tissue-specific Development in Zebrafish

por Rai, Kunal, Jafri, Itrat F., Chidester, Stephanie, James, Smitha R., Karpf, Adam R., Cairns, Bradley R., Jones, David A.
Publicado 2010

Identification of EMT signaling cross-talk and gene regulatory networks by single-cell RNA sequencing

por Deshmukh, Abhijeet P., Vasaikar, Suhas V., Tomczak, Katarzyna, Tripathi, Shubham, den Hollander, Petra, Arslan, Emre, Chakraborty, Priyanka, Soundararajan, Rama, Jolly, Mohit Kumar, Rai, Kunal, Levine, Herbert, Mani, Sendurai A.
Publicado 2021

B Cells Are Required to Generate Optimal Anti-Melanoma Immunity in Response to Checkpoint Blockade

por Singh, Shubhra, Roszik, Jason, Saini, Neeraj, Singh, Vipul Kumar, Bavisi, Karishma, Wang, Zhiqiang, Vien, Long T., Yang, Zixi, Kundu, Suprateek, Davis, Richard E., Bover, Laura, Diab, Adi, Neelapu, Sattva S., Overwijk, Willem W., Rai, Kunal, Singh, Manisha
Publicado 2022

KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary

por Hillman, R. Tyler, Celestino, Joseph, Terranova, Christopher, Beird, Hannah C., Gumbs, Curtis, Little, Latasha, Nguyen, Tri, Thornton, Rebecca, Tippen, Samantha, Zhang, Jianhua, Lu, Karen H., Gershenson, David M., Rai, Kunal, Broaddus, Russell R., Futreal, P. Andrew
Publicado 2018

Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor

por Adhikary, Santanu, Chakravarti, Deepavali, Terranova, Christopher, Sengupta, Isha, Maitituoheti, Mayinuer, Dasgupta, Anirban, Srivastava, Dushyant Kumar, Ma, Junsheng, Raman, Ayush T., Tarco, Emily, Sahin, Aysegul A., Bassett, Roland, Yang, Fei, Tapia, Coya, Roy, Siddhartha, Rai, Kunal, Das, Chandrima
Publicado 2019

High enhancer activity is an epigenetic feature of HPV negative atypical head and neck squamous cell carcinoma

por Callahan, S. Carson, Kochat, Veena, Liu, Zhiyi, Raman, Ayush T., Divenko, Margarita, Schulz, Jonathan, Terranova, Christopher J., Ghosh, Archit K., Tang, Ming, Johnson, Faye M., Wang, Jing, Skinner, Heath D, Pickering, Curtis R., Myers, Jeffrey N., Rai, Kunal
Publicado 2022

Semiconductor-based DNA sequencing of histone modification states

por Cheng, Christine S., Rai, Kunal, Garber, Manuel, Hollinger, Andrew, Robbins, Dana, Anderson, Scott, Macbeth, Alyssa, Tzou, Austin, Carneiro, Mauricio O., Raychowdhury, Raktima, Russ, Carsten, Hacohen, Nir, Gershenwald, Jeffrey E., Lennon, Niall, Nusbaum, Chad, Chin, Lynda, Regev, Aviv, Amit, Ido
Publicado 2013

Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance

por Fan, Huihui, Wang, Feng, Zeng, Andy, Murison, Alex, Tomczak, Katarzyna, Hao, Dapeng, Jelloul, Fatima Zahra, Wang, Bofei, Barrodia, Praveen, Liang, Shaoheng, Chen, Ken, Wang, Linghua, Zhao, Zhongming, Rai, Kunal, Jain, Abhinav K., Dick, John, Daver, Naval, Futreal, Andy, Abbas, Hussein A.
Publicado 2023

Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine

por Terranova, Christopher J., Stemler, Kristina M., Barrodia, Praveen, Jeter-Jones, Sabrina L., Ge, Zhongqi, de la Cruz Bonilla, Marimar, Raman, Ayush, Cheng, Chia-Wei, Allton, Kendra L., Arslan, Emre, Yilmaz, Ömer H., Barton, Michelle C., Rai, Kunal, Piwnica-Worms, Helen
Publicado 2021

Immune landscape of a genetically engineered murine model of glioma compared with human glioma

por Zamler, Daniel B., Shingu, Takashi, Kahn, Laura M., Huntoon, Kristin, Kassab, Cynthia, Ott, Martina, Tomczak, Katarzyna, Liu, Jintan, Li, Yating, Lai, Ivy, Zorilla-Veloz, Rocio, Yee, Cassian, Rai, Kunal, Kim, Betty Y.S., Watowich, Stephanie S., Heimberger, Amy B., Draetta, Giulio F., Hu, Jian
Publicado 2022

TIGIT is the central player in T-cell suppression associated with CAR T-cell relapse in mantle cell lymphoma

por Jiang, Vivian Changying, Hao, Dapeng, Jain, Preetesh, Li, Yijing, Cai, Qingsong, Yao, Yixin, Nie, Lei, Liu, Yang, Jin, Jingling, Wang, Wei, Lee, Heng-Huan, Che, Yuxuan, Dai, Enyu, Han, Guangchun, Wang, Ruiping, Rai, Kunal, Futreal, Andrew, Flowers, Christopher, Wang, Linghua, Wang, Michael
Publicado 2022

Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

por Osman, Abdullah A., Arslan, Emre, Bartels, Mason, Michikawa, Chieko, Lindemann, Antje, Tomczak, Katarzyna, Yu, Wangjie, Sandulache, Vlad, Ma, Wencai, Shen, Li, Wang, Jing, Singh, Anand K., Frederick, Mitchell J., Spencer, Nakia D., Kovacs, Jeffery, Heffernan, Timothy, Symmans, William F., Rai, Kunal, Myers, Jeffrey N.
Publicado 2023

TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes

por Oleksiewicz, Urszula, Gładych, Marta, Raman, Ayush T., Heyn, Holger, Mereu, Elisabetta, Chlebanowska, Paula, Andrzejewska, Anastazja, Sozańska, Barbara, Samant, Neha, Fąk, Katarzyna, Auguścik, Paulina, Kosiński, Marcin, Wróblewska, Joanna P., Tomczak, Katarzyna, Kulcenty, Katarzyna, Płoski, Rafał, Biecek, Przemysław, Esteller, Manel, Shah, Parantu K., Rai, Kunal, Wiznerowicz, Maciej
Publicado 2017

PRKCI promotes immune suppression in ovarian cancer

por Sarkar, Sharmistha, Bristow, Christopher A., Dey, Prasenjit, Rai, Kunal, Perets, Ruth, Ramirez-Cardenas, Alejandra, Malasi, Shruti, Huang-Hobbs, Emmet, Haemmerle, Monika, Wu, Sherry Y., McGuire, Michael, Protopopov, Alexei, Jiang, Shan, Liu, Joyce F., Hirsch, Michelle S., Chang, Qing, Lazar, Alexander J., Sood, Anil K., Drapkin, Ronny, DePinho, Ronald, Draetta, Giulio, Chin, Lynda
Publicado 2017

Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

por Terranova, Christopher J., Tang, Ming, Maitituoheti, Mayinuer, Raman, Ayush T., Ghosh, Archit K., Schulz, Jonathan, Amin, Samir B., Orouji, Elias, Tomczak, Katarzyna, Sarkar, Sharmistha, Oba, Junna, Creasy, Caitlin, Wu, Chang-Jiun, Khan, Samia, Lazcano, Rossana, Wani, Khalida, Singh, Anand, Barrodia, Praveen, Zhao, Dongyu, Chen, Kaifu, Haydu, Lauren E., Wang, Wei-Lien, Lazar, Alexander J., Woodman, Scott E., Bernatchez, Chantale, Rai, Kunal
Publicado 2021

Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8(+) T cells

por Manzo, Teresa, Prentice, Boone M., Anderson, Kristin G., Raman, Ayush, Schalck, Aislyn, Codreanu, Gabriela S., Nava Lauson, Carina B., Tiberti, Silvia, Raimondi, Andrea, Jones, Marissa A., Reyzer, Michelle, Bates, Breanna M., Spraggins, Jeffrey M., Patterson, Nathan H., McLean, John A., Rai, Kunal, Tacchetti, Carlo, Tucci, Sara, Wargo, Jennifer A., Rodighiero, Simona, Clise-Dwyer, Karen, Sherrod, Stacy D., Kim, Michael, Navin, Nicholas E., Caprioli, Richard M., Greenberg, Philip D., Draetta, Giulio, Nezi, Luigi
Publicado 2020

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma

por Maitituoheti, Mayinuer, Keung, Emily Z., Tang, Ming, Yan, Liang, Alam, Hunain, Han, Guangchun, Singh, Anand K., Raman, Ayush T., Terranova, Christopher, Sarkar, Sharmistha, Orouji, Elias, Amin, Samir B., Sharma, Sneha, Williams, Maura, Samant, Neha S., Dhamdhere, Mayura, Zheng, Norman, Shah, Tara, Shah, Amiksha, Axelrad, Jacob B., Anvar, Nazanin E., Lin, Yu-Hsi, Jiang, Shan, Chang, Edward Q., Ingram, Davis R., Wang, Wei-Lien, Lazar, Alexander, Lee, Min Gyu, Muller, Florian, Wang, Linghua, Ying, Haoqiang, Rai, Kunal
Publicado 2020

Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy

por Abbas, Hussein A., Hao, Dapeng, Tomczak, Katarzyna, Barrodia, Praveen, Im, Jin Seon, Reville, Patrick K., Alaniz, Zoe, Wang, Wei, Wang, Ruiping, Wang, Feng, Al-Atrash, Gheath, Takahashi, Koichi, Ning, Jing, Ding, Maomao, Beird, Hannah C., Mathews, Jairo T., Little, Latasha, Zhang, Jianhua, Basu, Sreyashi, Konopleva, Marina, Marques-Piubelli, Mario L., Solis, Luisa M., Parra, Edwin Roger, Lu, Wei, Tamegnon, Auriole, Garcia-Manero, Guillermo, Green, Michael R., Sharma, Padmanee, Allison, James P., Kornblau, Steven M., Rai, Kunal, Wang, Linghua, Daver, Naval, Futreal, Andrew
Publicado 2021

The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma

por Lamhamedi-Cherradi, Salah-Eddine, Maitituoheti, Mayinuer, Menegaz, Brian A., Krishnan, Sandhya, Vetter, Amelia M., Camacho, Pamela, Wu, Chia-Chin, Beird, Hannah C., Porter, Robert W., Ingram, Davis R., Ramamoorthy, Vandhana, Mohiuddin, Sana, McCall, David, Truong, Danh D., Cuglievan, Branko, Futreal, P. Andrew, Velasco, Alejandra Ruiz, Anvar, Nazanin Esmaeili, Utama, Budi, Titus, Mark, Lazar, Alexander J., Wang, Wei-Lien, Rodriguez-Aguayo, Cristian, Ratan, Ravin, Livingston, J. Andrew, Rai, Kunal, MacLeod, A. Robert, Daw, Najat C., Hayes-Jordan, Andrea, Ludwig, Joseph A.
Publicado 2022