Personalized Medicine Based on Nasal Epithelial Cells: Comparative Studies with Rectal Biopsies and Intestinal Organoids

por Silva, Iris A. L., Railean, Violeta, Duarte, Aires, Amaral, Margarida D.
Publicado 2021

Synthesis and the In Vitro Evaluation of Antitumor Activity of Novel Thiobenzanilides

por Álvaro-Martins, Maria João, Railean, Violeta, Martins, Filomena, Machuqueiro, Miguel, Pacheco, Rita, Santos, Susana
Publicado 2023

Synergy in Cystic Fibrosis Therapies: Targeting SLC26A9

por Pinto, Madalena C., Quaresma, Margarida C., Silva, Iris A. L., Railean, Violeta, Ramalho, Sofia S., Amaral, Margarida D.
Publicado 2021

Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells

por Santos, Lúcia, Nascimento, Rui, Duarte, Aires, Railean, Violeta, Amaral, Margarida D., Harrison, Patrick T., Gama-Carvalho, Margarida, Farinha, Carlos M.
Publicado 2023

Personalized medicine: Function of CFTR variant p.Arg334Trp is rescued by currently available CFTR modulators

por Railean, Violeta, Rodrigues, Cláudia S., Ramalho, Sofia S., Silva, Iris A. L., Bartosch, Jan, Farinha, Carlos M., Pankonien, Ines, Amaral, Margarida D.
Publicado 2023

TMEM16A chloride channel does not drive mucus production

por Simões, Filipa B, Quaresma, Margarida C, Clarke, Luka A, Silva, Iris AL, Pankonien, Ines, Railean, Violeta, Kmit, Arthur, Amaral, Margarida D
Publicado 2019

Mutant CFTR Drives TWIST1 mediated epithelial–mesenchymal transition

por Quaresma, Margarida C., Pankonien, Ines, Clarke, Luka A., Sousa, Luís S., Silva, Iris A. L., Railean, Violeta, Doušová, Tereza, Fuxe, Jonas, Amaral, Margarida D.
Publicado 2020

Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids

por Rodenburg, Lisa W., Delpiano, Livia, Railean, Violeta, Centeio, Raquel, Pinto, Madalena C., Smits, Shannon M. A., van der Windt, Isabelle S., van Hugten, Casper F. J., van Beuningen, Sam F. B., Rodenburg, Remco N. P., van der Ent, Cornelis K., Amaral, Margarida D., Kunzelmann, Karl, Gray, Michael A., Beekman, Jeffrey M., Amatngalim, Gimano D.
Publicado 2022