Evidence for substrate-assisted catalysis in N-acetylphosphoglucosamine mutase

por Raimi, Olawale G., Hurtado-Guerrero, Ramon, vanAalten, Daan M.F.
Publicado 2018

A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1

por Chen, Xiping, Raimi, Olawale G., Ferenbach, Andrew T., van Aalten, Daan M.F.
Publicado 2020

Genetic validation of Aspergillus fumigatus phosphoglucomutase as a viable therapeutic target in invasive aspergillosis

por Yan, Kaizhou, Stanley, Mathew, Kowalski, Bartosz, Raimi, Olawale G., Ferenbach, Andrew T., Wei, Pingzhen, Fang, Wenxia, van Aalten, Daan M.F.
Publicado 2022

A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor

por Raimi, Olawale G., Hurtado-Guerrero, Ramon, Borodkin, Vladimir, Ferenbach, Andrew, Urbaniak, Michael D., Ferguson, Michael A. J., van Aalten, Daan M. F.
Publicado 2020

Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations

por Kumar, Atul, Tamjar, Jevgenia, Waddell, Andrew D, Woodroof, Helen I, Raimi, Olawale G, Shaw, Andrew M, Peggie, Mark, Muqit, Miratul MK, van Aalten, Daan MF
Publicado 2017

Targeting a critical step in fungal hexosamine biosynthesis

por Lockhart, Deborah E. A., Stanley, Mathew, Raimi, Olawale G., Robinson, David A., Boldovjakova, Dominika, Squair, Daniel R., Ferenbach, Andrew T., Fang, Wenxia, van Aalten, Daan M. F.
Publicado 2020

Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target

por Fang, Wenxia, Du, Ting, Raimi, Olawale G, Hurtado-Guerrero, Ramon, Urbaniak, Michael D, Ibrahim, Adel F M, Ferguson, Michael A J, Jin, Cheng, Aalten, Daan M F
Publicado 2013

Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis

por Zhou, Yao, Yan, Kaizhou, Qin, Qijian, Raimi, Olawale G., Du, Chao, Wang, Bin, Ahamefule, Chukwuemeka Samson, Kowalski, Bartosz, Jin, Cheng, van Aalten, Daan M. F., Fang, Wenxia
Publicado 2022

Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal target

por Fang, Wenxia, Du, Ting, Raimi, Olawale G., Hurtado-Guerrero, Ramón, Mariño, Karina, Ibrahim, Adel F. M., Albarbarawi, Osama, Ferguson, Michael A. J., Jin, Cheng, Van Aalten, Daan M. F.
Publicado 2013

A Novel Allosteric Inhibitor of the Uridine Diphosphate N-Acetylglucosamine Pyrophosphorylase from Trypanosoma brucei

por Urbaniak, Michael D., Collie, Iain T., Fang, Wenxia, Aristotelous, Tonia, Eskilsson, Susanne, Raimi, Olawale G., Harrison, Justin, Navratilova, Iva Hopkins, Frearson, Julie A., van Aalten, Daan M. F., Ferguson, Michael A. J.
Publicado 2013

N-Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus

por Fang, Wenxia, Robinson, David A., Raimi, Olawale G., Blair, David E., Harrison, Justin R., Lockhart, Deborah E. A., Torrie, Leah S., Ruda, Gian Filippo, Wyatt, Paul G., Gilbert, Ian H., van Aalten, Daan M. F.
Publicado 2015

Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells

por Kakade, Poonam, Ojha, Hina, Raimi, Olawale G., Shaw, Andrew, Waddell, Andrew D., Ault, James R., Burel, Sophie, Brockmann, Kathrin, Kumar, Atul, Ahangar, Mohd Syed, Krysztofinska, Ewelina M., Macartney, Thomas, Bayliss, Richard, Fitzgerald, Julia C., Muqit, Miratul M. K.
Publicado 2022

N-Myristoyltransferase inhibitors as new leads to treat sleeping sickness

por Frearson, Julie A., Brand, Stephen, McElroy, Stuart P., Cleghorn, Laura A.T., Smid, Ondrej, Stojanovski, Laste, Price, Helen P., Guther, M. Lucia S., Torrie, Leah S., Robinson, David A., Hallyburton, Irene, Mpamhanga, Chidochangu P., Brannigan, James A., Wilkinson, Anthony J., Hodgkinson, Michael, Hui, Raymond, Qiu, Wei, Raimi, Olawale G., van Aalten, Daan M. F., Brenk, Ruth, Gilbert, Ian H., Read, Kevin D., Fairlamb, Alan H., Ferguson, Michael A. J., Smith, Deborah F., Wyatt, Paul G.
Publicado 2010